[Term] id: PR:Q9NRA1-3 name: platelet-derived growth factor C isoform h3 (human) def: "A platelet-derived growth factor C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRA1-3." [PRO:DNx, UniProtKB:Q9NRA1] comment: Category=organism-sequence. synonym: "hPDGFC/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NRA1-3 is_a: PR:Q9NRA1 ! platelet-derived growth factor C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NRA1-4 name: platelet-derived growth factor C isoform h4 (human) def: "A platelet-derived growth factor C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRA1-4." [PRO:DNx, UniProtKB:Q9NRA1] comment: Category=organism-sequence. synonym: "hPDGFC/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NRA1-4 is_a: PR:Q9NRA1 ! platelet-derived growth factor C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NRA1 name: platelet-derived growth factor C (human) def: "A platelet-derived growth factor C that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NRA1] comment: Category=organism-gene. synonym: "PDGFC" RELATED Gene-based [UniProtKB:Q9NRA1] synonym: "SCDGF" RELATED Gene-based [UniProtKB:Q9NRA1] synonym: "hPDGFC" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ174/PRO200" RELATED Gene-based [UniProtKB:Q9NRA1] synonym: "PDGF-C (human)" EXACT [UniProtKB:Q9NRA1] synonym: "VEGF-E (human)" EXACT [UniProtKB:Q9NRA1] synonym: "fallotein (human)" EXACT [UniProtKB:Q9NRA1] synonym: "spinal cord-derived growth factor (human)" EXACT [UniProtKB:Q9NRA1] xref: UniProtKB:Q9NRA1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000703 ! platelet-derived growth factor C relationship: has_gene_template HGNC:8801 ! PDGFC (human) [Term] id: PR:000000703 name: platelet-derived growth factor C def: "A platelet-derived growth factor with CUB domain that is a translation product of the human PDGFC gene or a 1:1 ortholog thereof. Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three stages of wound healing: inflammation, proliferation and remodeling." [PRO:CNA] comment: Category=gene. synonym: "PDGFC" EXACT PRO-short-label [PRO:DNx] synonym: "SCDGF" RELATED Gene-based [] synonym: "PDGF-C" EXACT [] synonym: "VEGF-E" EXACT [] synonym: "fallotein" EXACT [] synonym: "UNQ174/PRO200" RELATED Gene-based [] synonym: "spinal cord-derived growth factor" EXACT [] is_a: PR:000000675 ! platelet-derived growth factor with CUB domain [Term] id: PR:Q9NRA1-1 name: platelet-derived growth factor C isoform 1 (human) def: "A platelet-derived growth factor C isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hPDGFC/iso:1" EXACT PRO-short-label [PRO:DNx] xref: Reactome:R-HSA-381911 "PR:Q9NRA1-1 located_in GO:0000139" xref: Reactome:R-HSA-381912 "PR:Q9NRA1-1 located_in GO:0005788" xref: UniProtKB:Q9NRA1-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000754 ! platelet-derived growth factor C isoform 1 [Term] id: PR:Q9NRA1-2 name: platelet-derived growth factor C isoform h2 (human) def: "A platelet-derived growth factor C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRA1-2." [PRO:DNx, UniProtKB:Q9NRA1] comment: Category=organism-sequence. synonym: "hPDGFC/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NRA1-2 is_a: PR:Q9NRA1 ! platelet-derived growth factor C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000036572 name: platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form (human) def: "A platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form in human. UniProtKB:Q9NRA1-1, MOD:01149~PR:000050074." [PMID:16443219, PRO:CNA, PRO:DAN] comment: Category=organism-modification. synonym: "hPDGFC/iso:1/Sumo1+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9NRA1-1, MOD:01149~PR:000050074" EXACT PRO-proteoform-std [PRO:DAN] synonym: "UniProtKB:Q9NRA1-1, Lys-314, MOD:01149~PR:000050074" NARROW PRO-proteoform-std [PRO:DAN] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000983 ! platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form relationship: has_part MOD:01149 ! sumoylated lysine [Term] id: PR:000036570 name: platelet-derived growth factor C isoform 1 cleaved 1 (human) def: "A platelet-derived growth factor C isoform 1 cleaved 1 in human. UniProtKB:Q9NRA1-1, 226-345." [PMID:10806482, PMID:11297552, PMID:15911618, PRO:CNA] comment: Category=organism-modification. synonym: "hPDGFC/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9NRA1-1, 226-345" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000982 ! platelet-derived growth factor C isoform 1 cleaved 1