[Term]
id: PR:000000785
name: voltage-gated potassium channel KCND2
def: "A shal-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCND2 gene or a 1:1 ortholog thereof. Kv4.2 potassium channels play a critical role in postsynaptic excitability. They are modulated by phosphorylation as well as by association with Kv4 Channel Interacting Proteins (KChIPs). The N terminus contains an ER retention motif RKR that seems to be masked when associated to KChiPs. This masking increases surface expression." [PMID:12829703, PRO:CNA]
comment: Category=gene.
synonym: "KCND2" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1044" RELATED Gene-based []
synonym: "voltage-gated potassium channel subunit Kv4.2" EXACT []
xref: IUPHARobj:553
is_a: PR:000000710 ! shal-related voltage-gated potassium channel alpha subunit