[Term]
id: PR:P01730
name: T-cell surface glycoprotein CD4 (human)
def: "A CD4 molecule that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01730]
comment: Category=organism-gene.
synonym: "CD4" RELATED Gene-based [UniProtKB:P01730]
synonym: "hCD4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T4/Leu-3 (human)" EXACT [UniProtKB:P01730]
xref: UniProtKB:P01730
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001004 ! CD4 molecule
relationship: has_gene_template HGNC:1678 ! CD4 (human)

[Term]
id: PR:000028418
name: CD4 molecule, signal peptide removed form (human)
def: "A CD4 molecule, signal peptide removed form in human. UniProtKB:P01730, 26-458." [PRO:DNx]
comment: Category=organism-modification.
synonym: "hCD4/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014621" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P01730, 26-458" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-167542 "PR:000028418 located_in GO:0005886"
xref: Reactome:R-HSA-180575 "PR:000028418 located_in GO:0005789"
xref: Reactome:R-HSA-182147 "PR:000028418 located_in GO:0005769"
xref: Reactome:R-HSA-8869082 "PR:000028418 located_in GO:0030665"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000018304 ! CD4 molecule, signal peptide removed form

[Term]
id: PR:P01730-1
name: T-cell surface glycoprotein CD4 isoform 1 (human)
def: "A CD4 molecule isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCD4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01730-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003069 ! CD4 molecule isoform 1

[Term]
id: PR:000036630
name: CD4 molecule isoform 1 phosphorylated 1 (human)
def: "A CD4 molecule isoform 1 phosphorylated 1 in human." [PMID:3259291, PRO:CL]
comment: Category=organism-modification.
synonym: "hCD4/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003072 ! CD4 molecule isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000001004
name: CD4 molecule
def: "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." [PMID:15326605]
comment: Category=gene. Requested by=CL.
synonym: "CD4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T4/Leu-3" EXACT []
synonym: "T-cell surface glycoprotein CD4" EXACT []
synonym: "T-cell differentiation antigen L3T4" EXACT []
xref: PIRSF:PIRSF001977
is_a: PR:000000001 ! protein