[Term] id: PR:P20702 name: integrin alpha-X (human) def: "An integrin alpha-X that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "CD11C" RELATED Gene-based [UniProtKB:P20702] synonym: "ITGAX" RELATED Gene-based [UniProtKB:P20702] synonym: "hITGAX" EXACT PRO-short-label [PRO:DNx] synonym: "Leu M5 (human)" EXACT [UniProtKB:P20702] synonym: "CD11 antigen-like family member C (human)" EXACT [UniProtKB:P20702] synonym: "leukocyte adhesion receptor p150,95 (human)" EXACT [UniProtKB:P20702] synonym: "leukocyte adhesion glycoprotein p150,95 alpha chain (human)" EXACT [UniProtKB:P20702] xref: UniProtKB:P20702 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001013 ! integrin alpha-X relationship: has_gene_template HGNC:6152 ! ITGAX (human) [Term] id: PR:000001013 name: integrin alpha-X def: "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis." [UniProtKB:P20702] comment: Category=gene. Requested by=CL. synonym: "CD11C" RELATED Gene-based [] synonym: "CD11c" EXACT [] synonym: "ITGAX" EXACT PRO-short-label [PRO:DNx] synonym: "Leu M5" EXACT [] synonym: "CD11 antigen-like family member C" EXACT [] synonym: "leukocyte adhesion receptor p150,95" EXACT [] synonym: "leukocyte adhesion glycoprotein p150,95 alpha chain" EXACT [] xref: IUPHARobj:2454 is_a: PR:000001005 ! integrin alpha with A domain [Term] id: PR:000048068 name: integrin alpha-X, signal peptide removed form (human) def: "An integrin alpha-X (human) that has had the signal peptide removed. UniProtKB:P20702, 20-1163." [PRO:DNx, Reactome:R-HSA-202764] comment: Category=organism-modification. synonym: "PRO_0000016294" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hITGAX/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P20702, 20-1163" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-202764 "PR:000048068 located_in GO:0005886" xref: Reactome:R-HSA-6801289 "PR:000048068 located_in GO:0030667" xref: Reactome:R-HSA-6801305 "PR:000048068 located_in GO:0101003" xref: Reactome:R-HSA-6801314 "PR:000048068 located_in GO:0070821" intersection_of: PR:P20702 ! integrin alpha-X (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens