[Term]
id: PR:000047345
name: ezrin, initiator methionine removed phosphorylated 5 (human)
def: "An ezrin (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 567 of the amino acid sequence represented by UniProtKB:P15311. UniProtKB:P15311, 2-586, Thr-567, MOD:00047." [PRO:DNx, Reactome:R-HSA-374559]
comment: Category=organism-modification.
synonym: "hEZR/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000219408, Thr-567, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P15311, 2-586, Thr-567, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-374559 "PR:000047345 located_in GO:0005829"
is_a: PR:P15311 ! ezrin (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P15311-1
name: ezrin isoform 1 (human)
def: "An ezrin isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hEZR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15311-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001032 ! ezrin isoform 1

[Term]
id: PR:000001031
name: ezrin
def: "An erm protein that is a translation product of the human EZR gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "EZR" EXACT PRO-short-label [PRO:DNx]
synonym: "p81" BROAD [PRO:DNx]
synonym: "VIL2" RELATED Gene-based []
synonym: "villin-2" EXACT []
synonym: "cytovillin" EXACT []
is_a: PR:000001030 ! erm protein

[Term]
id: PR:000036588
name: ezrin isoform 1 phosphorylated 1 (human)
def: "An ezrin isoform 1 phosphorylated 1 in human. UniProtKB:P15311-1, Tyr-146/Tyr-354, MOD:00048." [PMID:1382070, PRO:CNA]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Tyr-146/Tyr-354, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001034 ! ezrin isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000036589
name: ezrin isoform 1 phosphorylated 2 (human)
def: "An ezrin isoform 1 phosphorylated 2 in human. UniProtKB:P15311-1, Ser-66, MOD:00046." [PMID:12840026, PMID:16438931, PRO:CNA]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Ser-66, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001035 ! ezrin isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P15311
name: ezrin (human)
def: "An ezrin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P15311]
comment: Category=organism-gene.
synonym: "EZR" RELATED Gene-based [UniProtKB:P15311]
synonym: "VIL2" RELATED Gene-based [UniProtKB:P15311]
synonym: "hEZR" EXACT PRO-short-label [PRO:DNx]
synonym: "p81 (human)" BROAD [UniProtKB:P15311]
synonym: "villin-2 (human)" EXACT [UniProtKB:P15311]
synonym: "cytovillin (human)" EXACT [UniProtKB:P15311]
xref: Reactome:R-HSA-9020826 "PR:P15311 located_in GO:0005829"
xref: UniProtKB:P15311
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001031 ! ezrin
relationship: has_gene_template HGNC:12691 ! EZR (human)

[Term]
id: PR:000036625
name: ezrin isoform 1 phosphorylated 6 (human)
def: "An ezrin isoform 1 phosphorylated 6 in human. UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047." [PMID:18852256, PRO:AL]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003042 ! ezrin isoform 1 phosphorylated 6
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000047346
name: ezrin, initiator methionine removed phosphorylated 1 (human)
def: "An ezrin (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 146 and 354 of the amino acid sequence represented by UniProtKB:P15311. UniProtKB:P15311, 2-586, Tyr-146/Tyr-354, MOD:00048." [PRO:DNx, Reactome:R-HSA-374572]
comment: Category=organism-modification.
synonym: "hEZR/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000219408, Tyr-146/Tyr-354, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P15311, 2-586, Tyr-146/Tyr-354, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-374572 "PR:000047346 located_in GO:0005829"
is_a: PR:P15311 ! ezrin (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000036592
name: ezrin isoform 1 phosphorylated 5 (human)
def: "An ezrin isoform 1 phosphorylated 5 in human. UniProtKB:P15311-1, Thr-567, MOD:00047." [PMID:16144865, PMID:18025306, PRO:AL, PRO:CNA]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Thr-567, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001040 ! ezrin isoform 1 phosphorylated 5
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000036591
name: ezrin isoform 1 phosphorylated 4 (human)
def: "An ezrin isoform 1 phosphorylated 4 in human. UniProtKB:P15311-1, Tyr-146/Tyr-191, MOD:00048|Thr-567, MOD:00047." [PMID:15647376, PRO:CNA]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Tyr-146/Tyr-191, MOD:00048|Thr-567, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001039 ! ezrin isoform 1 phosphorylated 4
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000036590
name: ezrin isoform 1 phosphorylated 3 (human)
def: "An ezrin isoform 1 phosphorylated 3 in human. UniProtKB:P15311-1, Tyr-191, MOD:00048." [PMID:15647376, PRO:CNA]
comment: Category=organism-modification.
synonym: "hEZR/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15311-1, Tyr-191, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001038 ! ezrin isoform 1 phosphorylated 3
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine