[Term]
id: PR:000025405
name: T-cell surface glycoprotein CD8 beta chain isoform 1
def: "A T-cell surface glycoprotein CD8 beta chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-1 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CD8B/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "CD8beta isoform M-1" EXACT [PMID:1541829]
is_a: PR:000001085 ! T-cell surface glycoprotein CD8 beta chain

[Term]
id: PR:000025407
name: T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form
def: "A T-cell surface glycoprotein CD8 beta chain isoform 1 that has had the signal peptide removed to yield the mature form." [PRO:DAN]
comment: Category=modification.
synonym: "CD8B/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000025405 ! T-cell surface glycoprotein CD8 beta chain isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000046654
name: T-cell surface glycoprotein CD8 beta chain, signal peptide removed form (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that has had the signal peptide removed. UniProtKB:P10966, 22-210." [PRO:DNx, Reactome:R-HSA-2980537, Reactome:R-HSA-3149571]
comment: Category=organism-modification.
synonym: "hCD8B/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014643" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P10966, 22-210" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3149571 "PR:000046654 located_in GO:0031901"
xref: Reactome:R-HSA-2980537 "PR:000046654 located_in GO:0005886"
intersection_of: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000018337
name: T-cell surface glycoprotein CD8 beta chain, signal peptide removed form
def: "A T-cell surface glycoprotein CD8 beta chain that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD8B/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000001085 ! T-cell surface glycoprotein CD8 beta chain
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P10966
name: T-cell surface glycoprotein CD8 beta chain (human)
def: "A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P10966]
comment: Category=organism-gene.
synonym: "CD8B" RELATED Gene-based [UniProtKB:P10966]
synonym: "CD8B1" RELATED Gene-based [UniProtKB:P10966]
synonym: "hCD8B" EXACT PRO-short-label [PRO:DNx]
synonym: "CD8b (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001085 ! T-cell surface glycoprotein CD8 beta chain
relationship: has_gene_template HGNC:1707 ! CD8B (human)

[Term]
id: PR:P10966-9
name: T-cell surface glycoprotein CD8 beta chain isoform h8 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-9." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h8" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Sbeta5 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-9
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025409
name: T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed glycosylated form
def: "A T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN]
comment: Category=modification.
synonym: "CD8B/iso:1/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00693 ! glycosylated residue
intersection_of: PR:000025407 ! T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form

[Term]
id: PR:P10966-7
name: T-cell surface glycoprotein CD8 beta chain isoform h6 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-7." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Sbeta1 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-7
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10966-6
name: T-cell surface glycoprotein CD8 beta chain isoform h5 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-6." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Mbeta3 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-6
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10966-2
name: T-cell surface glycoprotein CD8 beta chain isoform h2 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-2." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform M-3 (human)" EXACT [UniProtKB:P10966]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Mbeta2 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-2
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10966-4
name: T-cell surface glycoprotein CD8 beta chain isoform h4 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-4." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform M-2 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-4
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10966-8
name: T-cell surface glycoprotein CD8 beta chain isoform h7 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-8." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Sbeta4 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-8
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05541
name: T-cell surface glycoprotein CD8 beta chain (rat)
def: "A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-gene.
synonym: "Cd8b" RELATED Gene-based [UniProtKB:P05541]
synonym: "Cd8b1" RELATED Gene-based [UniProtKB:P05541]
synonym: "rCD8B" EXACT PRO-short-label [PRO:DNx]
synonym: "CD8b (rat)" EXACT [UniProtKB:P05541]
synonym: "OX-8 membrane antigen (rat)" RELATED [UniProtKB:P05541]
synonym: "CD8 antigen 37 kDa chain (rat)" EXACT [UniProtKB:P05541]
xref: UniProtKB:P05541
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000001085 ! T-cell surface glycoprotein CD8 beta chain
relationship: has_gene_template RGD:2317 ! Cd8b (rat)

[Term]
id: PR:P10966-3
name: T-cell surface glycoprotein CD8 beta chain isoform h3 (human)
def: "A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-3." [PRO:DNx, UniProtKB:P10966]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform S-1 (human)" EXACT [UniProtKB:P10966]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Sbeta3 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-3
is_a: PR:P10966 ! T-cell surface glycoprotein CD8 beta chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10966-1
name: T-cell surface glycoprotein CD8 beta chain isoform 1 (human)
def: "A T-cell surface glycoprotein CD8 beta chain isoform 1 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCD8B/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform M-1 (human)" EXACT [UniProtKB:P10966]
synonym: "T-cell surface glycoprotein CD8 beta chain isoform Mbeta1 (human)" EXACT [UniProtKB:P10966]
xref: UniProtKB:P10966-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025405 ! T-cell surface glycoprotein CD8 beta chain isoform 1

[Term]
id: PR:000001085
name: T-cell surface glycoprotein CD8 beta chain
def: "A protein that is a translation product of the human CD8B gene or a 1:1 ortholog thereof. CD8 is a transmembrane receptor that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PRO:CNA, Wikipedia:CD8]
comment: Category=gene.
synonym: "CD8B" EXACT PRO-short-label [PRO:DNx]
synonym: "Ly-3" RELATED Gene-based []
synonym: "Lyt3" RELATED Gene-based []
synonym: "CD8B1" RELATED Gene-based []
synonym: "Lyt-3" RELATED Gene-based []
synonym: "lymphocyte antigen 3" EXACT []
synonym: "T-cell membrane glycoprotein Ly-3" EXACT []
synonym: "T-cell surface glycoprotein Lyt-3" EXACT []
xref: PIRSF:PIRSF002020
is_a: PR:000000001 ! protein

[Term]
id: PR:P10300
name: T-cell surface glycoprotein CD8 beta chain (mouse)
def: "A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-gene.
synonym: "Cd8b" RELATED Gene-based [UniProtKB:P10300]
synonym: "Ly-3" RELATED Gene-based [UniProtKB:P10300]
synonym: "Lyt3" RELATED Gene-based [UniProtKB:P10300]
synonym: "Cd8b1" RELATED Gene-based [UniProtKB:P10300]
synonym: "Lyt-3" RELATED Gene-based [UniProtKB:P10300]
synonym: "mCD8B" EXACT PRO-short-label [PRO:DNx]
synonym: "CD8b (mouse)" EXACT [UniProtKB:P10300]
synonym: "lymphocyte antigen 3 (mouse)" EXACT [UniProtKB:P10300]
synonym: "T-cell membrane glycoprotein Ly-3 (mouse)" EXACT [UniProtKB:P10300]
synonym: "T-cell surface glycoprotein Lyt-3 (mouse)" EXACT [UniProtKB:P10300]
xref: UniProtKB:P10300
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001085 ! T-cell surface glycoprotein CD8 beta chain
relationship: has_gene_template MGI:88347 ! Cd8b1 (mouse)