[Term]
id: PR:O15455
name: Toll-like receptor 3 (human)
def: "A Toll-like receptor 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O15455]
comment: Category=organism-gene.
synonym: "TLR3" RELATED Gene-based [UniProtKB:O15455]
synonym: "hTLR3" EXACT PRO-short-label [PRO:DNx]
synonym: "CD283 (human)" EXACT [UniProtKB:O15455]
xref: UniProtKB:O15455
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001154 ! Toll-like receptor 3
relationship: has_gene_template HGNC:11849 ! TLR3 (human)

[Term]
id: PR:O15455-1
name: Toll-like receptor 3 isoform h1 (human)
def: "A Toll-like receptor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15455-1." [PRO:DNx, UniProtKB:O15455]
comment: Category=organism-sequence.
synonym: "hTLR3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15455-1
is_a: PR:O15455 ! Toll-like receptor 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15455-2
name: Toll-like receptor 3 isoform h2 (human)
def: "A Toll-like receptor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15455-2." [PRO:DNx, UniProtKB:O15455]
comment: Category=organism-sequence.
synonym: "hTLR3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15455-2
is_a: PR:O15455 ! Toll-like receptor 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037305
name: Toll-like receptor 3, signal peptide removed form (human)
def: "A Toll-like receptor 3, signal peptide removed form in human. Example: UniProtKB:O15455-1, 24-904." [PMID:15340161, PRO:CNA, Reactome:R-HSA-1678955, Reactome:R-HSA-1679057, Reactome:R-HSA-167941, Reactome:R-HSA-2000341]
comment: Category=organism-modification.
synonym: "hTLR3/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15455-1, 24-904" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-167941 "PR:000037305 located_in GO:0036020"
xref: Reactome:R-HSA-1678955 "PR:000037305 located_in GO:0000139"
xref: Reactome:R-HSA-1679057 "PR:000037305 located_in GO:0005789"
xref: Reactome:R-HSA-2000341 "PR:000037305 located_in GO:0010008"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000018357 ! Toll-like receptor 3, signal peptide removed form

[Term]
id: PR:000001154
name: Toll-like receptor 3
def: "A Toll-like receptor that is a translation product of the human TLR3 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "TLR3" EXACT PRO-short-label [PRO:DNx]
synonym: "CD283" EXACT []
xref: IUPHARobj:1753
is_a: PR:000001096 ! Toll-like receptor