[Term]
id: PR:000001159
name: Toll-like receptor 8
def: "A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "TLR8" EXACT PRO-short-label [PRO:DNx]
synonym: "CD288" EXACT []
synonym: "UNQ249/PRO286" RELATED Gene-based []
xref: IUPHARobj:1758
is_a: PR:000001096 ! Toll-like receptor

[Term]
id: PR:Q9NR97-1
name: Toll-like receptor 8 isoform 1 (human)
def: "A Toll-like receptor 8 isoform 1 that is encoded in the genome of human." [PMID:20004021, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hTLR8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NR97-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027944 ! Toll-like receptor 8 isoform 1

[Term]
id: PR:000049471
name: Toll-like receptor 8, signal peptide removed form (human)
def: "A Toll-like receptor 8 (human) that has had the signal peptide removed. UniProtKB:Q9NR97, 27-1041." [PRO:DNx, Reactome:R-HSA-1678918, Reactome:R-HSA-1678947, Reactome:R-HSA-167927, Reactome:R-HSA-1679577]
comment: Category=organism-modification.
synonym: "hTLR8/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000034735" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9NR97, 27-1041" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-167927 "PR:000049471 located_in GO:0036020"
xref: Reactome:R-HSA-1678918 "PR:000049471 located_in GO:0000139"
xref: Reactome:R-HSA-1678947 "PR:000049471 located_in GO:0005789"
xref: Reactome:R-HSA-1679577 "PR:000049471 located_in GO:0010008"
intersection_of: PR:Q9NR97 ! Toll-like receptor 8 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NR97-2
name: Toll-like receptor 8 isoform h2 (human)
def: "A Toll-like receptor 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR97-2." [PRO:DNx, UniProtKB:Q9NR97]
comment: Category=organism-sequence.
synonym: "hTLR8/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NR97-2
is_a: PR:Q9NR97 ! Toll-like receptor 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NR97
name: Toll-like receptor 8 (human)
def: "A Toll-like receptor 8 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NR97]
comment: Category=organism-gene.
synonym: "TLR8" RELATED Gene-based [UniProtKB:Q9NR97]
synonym: "hTLR8" EXACT PRO-short-label [PRO:DNx]
synonym: "CD288 (human)" EXACT [UniProtKB:Q9NR97]
synonym: "UNQ249/PRO286" RELATED Gene-based [UniProtKB:Q9NR97]
xref: UniProtKB:Q9NR97
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001159 ! Toll-like receptor 8
relationship: has_gene_template HGNC:15632 ! TLR8 (human)