[Term]
id: PR:P20273-2
name: B-cell receptor CD22 isoform hCD22-alpha (human)
def: "A B-cell receptor CD22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20273-2." [PRO:DNx, UniProtKB:P20273]
comment: Category=organism-sequence.
synonym: "hCD22/iso:hCD22-alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20273-2
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20273-3
name: B-cell receptor CD22 isoform h3 (human)
def: "A B-cell receptor CD22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20273-3." [PRO:DNx, UniProtKB:P20273]
comment: Category=organism-sequence.
synonym: "hCD22/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20273-3
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20273-1
name: B-cell receptor CD22 isoform hCD22-beta (human)
def: "A B-cell receptor CD22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20273-1." [PRO:DNx, UniProtKB:P20273]
comment: Category=organism-sequence.
synonym: "hCD22/iso:hCD22-beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20273-1
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20273-4
name: B-cell receptor CD22 isoform h4 (human)
def: "A B-cell receptor CD22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20273-4." [PRO:DNx, UniProtKB:P20273]
comment: Category=organism-sequence.
synonym: "hCD22/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20273-4
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20273-5
name: B-cell receptor CD22 isoform h5 (human)
def: "A B-cell receptor CD22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20273-5." [PRO:DNx, UniProtKB:P20273]
comment: Category=organism-sequence.
synonym: "hCD22/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20273-5
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001288
name: B-cell receptor CD22
def: "A protein that is a translation product of the human CD22 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD22" EXACT PRO-short-label [PRO:DNx]
synonym: "Lyb-8" RELATED Gene-based []
synonym: "BL-CAM" EXACT []
synonym: "SIGLEC2" RELATED Gene-based []
synonym: "siglec-2" EXACT []
synonym: "T-cell surface antigen Leu-14" EXACT []
synonym: "B-lymphocyte cell adhesion molecule" EXACT []
synonym: "sialic acid-binding Ig-like lectin 2" EXACT []
xref: IUPHARobj:2786
is_a: PR:000000001 ! protein

[Term]
id: PR:P20273
name: B-cell receptor CD22 (human)
def: "A B-cell receptor CD22 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P20273]
comment: Category=organism-gene.
synonym: "CD22" RELATED Gene-based [UniProtKB:P20273]
synonym: "hCD22" EXACT PRO-short-label [PRO:DNx]
synonym: "SIGLEC2" RELATED Gene-based [UniProtKB:P20273]
synonym: "BL-CAM (human)" EXACT [UniProtKB:P20273]
synonym: "siglec-2 (human)" EXACT [UniProtKB:P20273]
synonym: "T-cell surface antigen Leu-14 (human)" EXACT [UniProtKB:P20273]
synonym: "B-lymphocyte cell adhesion molecule (human)" EXACT [UniProtKB:P20273]
synonym: "sialic acid-binding Ig-like lectin 2 (human)" EXACT [UniProtKB:P20273]
xref: UniProtKB:P20273
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001288 ! B-cell receptor CD22
relationship: has_gene_template HGNC:1643 ! CD22 (human)

[Term]
id: PR:000046622
name: B-cell receptor CD22, signal peptide removed phosphorylated 1 (human)
def: "A B-cell receptor CD22 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 762, 807 and 822 of the amino acid sequence represented by UniProtKB:P20273. UniProtKB:P20273, 20-847, Tyr-762/Tyr-807/Tyr-822, MOD:00048." [PRO:DNx, Reactome:R-HSA-5690726]
comment: Category=organism-modification.
synonym: "hCD22/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014873, Tyr-762/Tyr-807/Tyr-822, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P20273, 20-847, Tyr-762/Tyr-807/Tyr-822, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5690726 "PR:000046622 located_in GO:0005886"
is_a: PR:P20273 ! B-cell receptor CD22 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000046621
name: B-cell receptor CD22, signal peptide removed form (human)
def: "A B-cell receptor CD22 (human) that has had the signal peptide removed. UniProtKB:P20273, 20-847." [PRO:DNx, Reactome:R-HSA-197703]
comment: Category=organism-modification.
synonym: "hCD22/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014873" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P20273, 20-847" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197703 "PR:000046621 located_in GO:0005886"
intersection_of: PR:P20273 ! B-cell receptor CD22 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens