[Term] id: PR:000001393 name: interleukin-6 def: "A protein that is a translation product of the human IL6 gene or a 1:1 ortholog thereof." [PRO:JAN] comment: Category=gene. synonym: "CDF" EXACT [] synonym: "IL6" EXACT PRO-short-label [PRO:DNx] synonym: "IL-6" EXACT [] synonym: "BSF-2" EXACT [] synonym: "IFNB2" RELATED Gene-based [] synonym: "IFN-beta-2" EXACT [] synonym: "interleukin HP-1" EXACT [] synonym: "interferon beta-2" EXACT [] synonym: "hybridoma growth factor" EXACT [] synonym: "CTL differentiation factor" EXACT [] synonym: "B-cell stimulatory factor 2" EXACT [] synonym: "B-cell hybridoma growth factor" EXACT [] xref: PIRSF:PIRSF001935 is_a: PR:000000001 ! protein [Term] id: PR:P05231 name: interleukin-6 (human) def: "An interleukin-6 that is encoded in the genome of human." [PRO:JAN, UniProtKB:P05231] comment: Category=organism-gene. synonym: "IL6" RELATED Gene-based [UniProtKB:P05231] synonym: "hIL6" EXACT PRO-short-label [PRO:DNx] synonym: "IFNB2" RELATED Gene-based [UniProtKB:P05231] synonym: "CDF (human)" EXACT [UniProtKB:P05231] synonym: "IL-6 (human)" EXACT [UniProtKB:P05231] synonym: "BSF-2 (human)" EXACT [UniProtKB:P05231] synonym: "IFN-beta-2 (human)" EXACT [UniProtKB:P05231] synonym: "interferon beta-2 (human)" EXACT [UniProtKB:P05231] synonym: "hybridoma growth factor (human)" EXACT [UniProtKB:P05231] synonym: "CTL differentiation factor (human)" EXACT [UniProtKB:P05231] synonym: "B-cell stimulatory factor 2 (human)" EXACT [UniProtKB:P05231] xref: UniProtKB:P05231 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001393 ! interleukin-6 relationship: has_gene_template HGNC:6018 ! IL6 (human) [Term] id: PR:000048028 name: interleukin-6, signal peptide removed form (human) def: "An interleukin-6 (human) that has had the signal peptide removed. UniProtKB:P05231, 30-212." [PRO:DNx, Reactome:R-HSA-447100] comment: Category=organism-modification. synonym: "hIL6/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015582" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P05231, 30-212" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-447100 "PR:000048028 located_in GO:0005576" xref: Reactome:R-HSA-8956764 "PR:000048028 located_in GO:0005788" intersection_of: PR:P05231 ! interleukin-6 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens