[Term] id: PR:000054603 name: interleukin-6 receptor subunit alpha O-glycosylated 2 (human) def: "An interleukin-6 receptor subunit alpha (human) that has been O-glycosylated at the residue equivalent to Thr-335 of the amino acid sequence represented by UniProtKB:P08887-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P08887-1, Thr-335, MOD:00005~GNO:G53434XO." [GlyGen:P08887-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hIL6R/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08887-1, Thr-335, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08887 ! interleukin-6 receptor subunit alpha (human) relationship: has_part GNO:G53434XO ! G53434XO relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000054602 name: interleukin-6 receptor subunit alpha O-glycosylated 1 (human) def: "An interleukin-6 receptor subunit alpha (human) that has been O-glycosylated at the residue equivalent to Thr-329 of the amino acid sequence represented by UniProtKB:P08887-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08887-1, Thr-329, MOD:00005~GNO:G43417UB." [GlyGen:P08887-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hIL6R/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08887-1, Thr-329, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08887 ! interleukin-6 receptor subunit alpha (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08887-1 name: interleukin-6 receptor subunit alpha isoform 1 (human) def: "An interleukin-6 receptor subunit alpha isoform 2 that is encoded in the genome of human." [PRO:HJD] comment: Category=organism-sequence. synonym: "hIL6R/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "interleukin-6 receptor subunit alpha isoform Long (human)" EXACT [UniProtKB:P08887] xref: UniProtKB:P08887-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001795 ! interleukin-6 receptor subunit alpha isoform 2 [Term] id: PR:000001394 name: interleukin-6 receptor subunit alpha def: "A protein that is a translation product of the human IL6R gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "IL6R" EXACT PRO-short-label [PRO:DNx] synonym: "gp80" EXACT [] synonym: "CD126" EXACT [] synonym: "Il6ra" RELATED Gene-based [] synonym: "IL-6RA" EXACT [] synonym: "IL-6R 1" EXACT [] synonym: "IL-6R-alpha" EXACT [] synonym: "IL-6R subunit alpha" EXACT [] synonym: "membrane glycoprotein 80" EXACT [] synonym: "IL-6 receptor subunit alpha" EXACT [] xref: IUPHARobj:1708 is_a: PR:000000001 ! protein [Term] id: PR:P08887 name: interleukin-6 receptor subunit alpha (human) def: "An interleukin-6 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08887] comment: Category=organism-gene. synonym: "IL6R" RELATED Gene-based [UniProtKB:P08887] synonym: "hIL6R" EXACT PRO-short-label [PRO:DNx] synonym: "gp80 (human)" EXACT [UniProtKB:P08887] synonym: "CD126 (human)" EXACT [UniProtKB:P08887] synonym: "IL-6RA (human)" EXACT [UniProtKB:P08887] synonym: "IL-6R 1 (human)" EXACT [UniProtKB:P08887] synonym: "IL-6R-alpha (human)" EXACT [UniProtKB:P08887] synonym: "IL-6R subunit alpha (human)" EXACT [UniProtKB:P08887] synonym: "membrane glycoprotein 80 (human)" EXACT [UniProtKB:P08887] synonym: "IL-6 receptor subunit alpha (human)" EXACT [UniProtKB:P08887] xref: UniProtKB:P08887 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001394 ! interleukin-6 receptor subunit alpha relationship: has_gene_template HGNC:6019 ! IL6R (human) [Term] id: PR:000048029 name: interleukin-6 receptor subunit alpha, signal peptide removed form (human) def: "An interleukin-6 receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P08887, 20-468." [PRO:DNx, Reactome:R-HSA-197824] comment: Category=organism-modification. synonym: "hIL6R/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000010895" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P08887, 20-468" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-197824 "PR:000048029 located_in GO:0005886" intersection_of: PR:P08887 ! interleukin-6 receptor subunit alpha (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08887-2 name: interleukin-6 receptor subunit alpha isoform 2 (human) def: "An interleukin-6 receptor subunit alpha isoform 3 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hIL6R/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "interleukin-6 receptor subunit alpha isoform Short (human)" EXACT [UniProtKB:P08887] xref: UniProtKB:P08887-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001796 ! interleukin-6 receptor subunit alpha isoform 3