[Term] id: PR:000001543 name: programmed cell death 1 ligand 1 def: "A B7-related protein that is a translation product of the human CD274 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "B7H1" RELATED Gene-based [] synonym: "PDL1" RELATED Gene-based [] synonym: "B7-H1" EXACT [] synonym: "CD274" EXACT PRO-short-label [PRO:DNx] synonym: "PD-L1" EXACT [] synonym: "PDCD1L1" RELATED Gene-based [] synonym: "PDCD1LG1" RELATED Gene-based [] synonym: "B7 homolog 1" EXACT [] synonym: "PDCD1 ligand 1" EXACT [] synonym: "programmed death ligand 1" EXACT [] is_a: PR:000001290 ! B7-related protein [Term] id: PR:000046626 name: programmed cell death 1 ligand 1, signal peptide removed form (human) def: "A programmed cell death 1 ligand 1 (human) that has had the signal peptide removed. UniProtKB:Q9NZQ7, 19-290." [PRO:DNx, Reactome:R-HSA-3211776] comment: Category=organism-modification. synonym: "PRO_0000014553" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hCD274/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9NZQ7, 19-290" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-3211776 "PR:000046626 located_in GO:0005886" intersection_of: PR:Q9NZQ7 ! programmed cell death 1 ligand 1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9EP73 name: programmed cell death 1 ligand 1 (mouse) def: "A programmed cell death 1 ligand 1 that is encoded in the genome of mouse." [OMA:Q9EP73, PRO:DNx] comment: Category=organism-gene. synonym: "B7h1" RELATED Gene-based [UniProtKB:Q9EP73] synonym: "Pdl1" RELATED Gene-based [UniProtKB:Q9EP73] synonym: "Cd274" RELATED Gene-based [UniProtKB:Q9EP73] synonym: "mCD274" EXACT PRO-short-label [PRO:DNx] synonym: "Pdcd1l1" RELATED Gene-based [UniProtKB:Q9EP73] synonym: "Pdcd1lg1" RELATED Gene-based [UniProtKB:Q9EP73] synonym: "B7-H1 (mouse)" EXACT [UniProtKB:Q9EP73] synonym: "CD274 (mouse)" EXACT [UniProtKB:Q9EP73] synonym: "PD-L1 (mouse)" EXACT [UniProtKB:Q9EP73] synonym: "B7 homolog 1 (mouse)" EXACT [UniProtKB:Q9EP73] synonym: "PDCD1 ligand 1 (mouse)" EXACT [UniProtKB:Q9EP73] synonym: "programmed death ligand 1 (mouse)" EXACT [UniProtKB:Q9EP73] xref: UniProtKB:Q9EP73 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000001543 ! programmed cell death 1 ligand 1 relationship: has_gene_template MGI:1926446 ! Cd274 (mouse) [Term] id: PR:Q9NZQ7-2 name: programmed cell death 1 ligand 1 isoform h2 (human) def: "A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-2." [PRO:DNx, UniProtKB:Q9NZQ7] comment: Category=organism-sequence. synonym: "hCD274/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "programmed cell death 1 ligand 1 isoform PD-L1II (human)" EXACT [UniProtKB:Q9NZQ7] xref: UniProtKB:Q9NZQ7-2 is_a: PR:Q9NZQ7 ! programmed cell death 1 ligand 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NZQ7-3 name: programmed cell death 1 ligand 1 isoform h3 (human) def: "A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-3." [PRO:DNx, UniProtKB:Q9NZQ7] comment: Category=organism-sequence. synonym: "hCD274/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NZQ7-3 is_a: PR:Q9NZQ7 ! programmed cell death 1 ligand 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NZQ7-1 name: programmed cell death 1 ligand 1 isoform h1 (human) def: "A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-1." [PRO:DNx, UniProtKB:Q9NZQ7] comment: Category=organism-sequence. synonym: "hCD274/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "programmed cell death 1 ligand 1 isoform PD-L1I (human)" EXACT [UniProtKB:Q9NZQ7] xref: UniProtKB:Q9NZQ7-1 is_a: PR:Q9NZQ7 ! programmed cell death 1 ligand 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NZQ7 name: programmed cell death 1 ligand 1 (human) def: "A programmed cell death 1 ligand 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9NZQ7] comment: Category=organism-gene. synonym: "B7H1" RELATED Gene-based [UniProtKB:Q9NZQ7] synonym: "PDL1" RELATED Gene-based [UniProtKB:Q9NZQ7] synonym: "CD274" RELATED Gene-based [UniProtKB:Q9NZQ7] synonym: "hCD274" EXACT PRO-short-label [PRO:DNx] synonym: "hPD-L1" EXACT [UniProtKB:Q9NZQ7] synonym: "PDCD1L1" RELATED Gene-based [UniProtKB:Q9NZQ7] synonym: "PDCD1LG1" RELATED Gene-based [UniProtKB:Q9NZQ7] synonym: "B7-H1 (human)" EXACT [UniProtKB:Q9NZQ7] synonym: "PD-L1 (human)" EXACT [UniProtKB:Q9NZQ7] synonym: "B7 homolog 1 (human)" EXACT [UniProtKB:Q9NZQ7] synonym: "PDCD1 ligand 1 (human)" EXACT [UniProtKB:Q9NZQ7] synonym: "programmed death ligand 1 (human)" EXACT [UniProtKB:Q9NZQ7] xref: UniProtKB:Q9NZQ7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001543 ! programmed cell death 1 ligand 1 relationship: has_gene_template HGNC:17635 ! CD274 (human)