[Term] id: PR:000049365 name: signal transducer and activator of transcription 2 phosphorylated 1 (human) def: "A signal transducer and activator of transcription 2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-690 of the amino acid sequence represented by UniProtKB:P52630. UniProtKB:P52630, Tyr-690, MOD:00048." [PRO:DNx, Reactome:R-HSA-909673, Reactome:R-HSA-909683] comment: Category=organism-modification. synonym: "hSTAT2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P52630, Tyr-690, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-909673 "PR:000049365 located_in GO:0005654" xref: Reactome:R-HSA-909683 "PR:000049365 located_in GO:0005829" is_a: PR:P52630 ! signal transducer and activator of transcription 2 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000002088 name: signal transducer and activator of transcription 2 def: "A signal transducer and transcription activator STAT that is a translation product of the human STAT2 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "p113" BROAD [PRO:DNx] synonym: "STAT2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001933 ! signal transducer and transcription activator STAT [Term] id: PR:P52630-3 name: signal transducer and activator of transcription 2 isoform 1 (human) def: "A signal transducer and activator of transcription 2 isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hSTAT2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P52630-3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028651 ! signal transducer and activator of transcription 2 isoform 1 [Term] id: PR:P52630-4 name: signal transducer and activator of transcription 2 isoform 2 (human) def: "A signal transducer and activator of transcription 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52630-4." [PRO:DNx, UniProtKB:P52630] comment: Category=organism-sequence. synonym: "hSTAT2/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P52630-4 is_a: PR:P52630 ! signal transducer and activator of transcription 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P52630 name: signal transducer and activator of transcription 2 (human) def: "A signal transducer and activator of transcription 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P52630] comment: Category=organism-gene. synonym: "STAT2" RELATED Gene-based [UniProtKB:P52630] synonym: "hSTAT2" EXACT PRO-short-label [PRO:DNx] synonym: "p113 (human)" BROAD [UniProtKB:P52630] xref: Reactome:R-HSA-882029 "PR:P52630 located_in GO:0005829" xref: UniProtKB:P52630 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002088 ! signal transducer and activator of transcription 2 relationship: has_gene_template HGNC:11363 ! STAT2 (human) [Term] id: PR:000028654 name: signal transducer and activator of transcription 2 isoform 1 acetylated 1 (human) def: "A signal transducer and activator of transcription 2 isoform 1 acetylated 1 in human. UniProtKB:P52630-3, Lys-182/Lys-184/Lys-194/Lys-197/Lys-384/Lys-390/Lys-415/Lys-419/Lys-592, MOD:00064." [PMID:17923090, PRO:PD] comment: Category=organism-modification. Acetylase=("CREBBP"; PR:Q92793). synonym: "hSTAT2/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P52630-3, Lys-182/Lys-184/Lys-194/Lys-197/Lys-384/Lys-390/Lys-415/Lys-419/Lys-592, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028653 ! signal transducer and activator of transcription 2 isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine