[Term]
id: PR:000036224
name: Bcl-2 homologous antagonist/killer acetylated 1 (human)
def: "A Bcl-2 homologous antagonist/killer that is N-terminal Met acetylated in human. Example: UniProtKB:Q16611-1, Met-1, MOD:00058." [TDR:1709]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hBAK1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16611-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:1709
is_a: PR:000002185 ! Bcl-2 homologous antagonist/killer
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002185
name: Bcl-2 homologous antagonist/killer
def: "A protein that is a translation product of the human BAK1 gene or a 1:1 ortholog thereof. The BAK2 gene is a recent duplication in humans and gives rise to a very similar protein." [PRO:WCB]
comment: Category=gene.
synonym: "BAK" RELATED Gene-based []
synonym: "BAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CDN1" RELATED Gene-based []
synonym: "BCL2L7" RELATED Gene-based []
synonym: "Bcl2-L-7" EXACT []
synonym: "Bcl-2-like protein 7" EXACT []
synonym: "apoptosis regulator BAK" EXACT []
synonym: "Bcl2 homologous antagonist/killer" EXACT []
xref: PIRSF:PIRSF038829
is_a: PR:000000001 ! protein

[Term]
id: PR:Q16611-2
name: Bcl-2 homologous antagonist/killer isoform h2 (human)
def: "A Bcl-2 homologous antagonist/killer (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16611-2." [PRO:DNx, UniProtKB:Q16611]
comment: Category=organism-sequence.
synonym: "hBAK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16611-2
is_a: PR:Q16611 ! Bcl-2 homologous antagonist/killer (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16611
name: Bcl-2 homologous antagonist/killer (human)
def: "A Bcl-2 homologous antagonist/killer that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q16611]
comment: Category=organism-gene.
synonym: "BAK" RELATED Gene-based [UniProtKB:Q16611]
synonym: "BAK1" RELATED Gene-based [UniProtKB:Q16611]
synonym: "CDN1" RELATED Gene-based [UniProtKB:Q16611]
synonym: "hBAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "BCL2L7" RELATED Gene-based [UniProtKB:Q16611]
synonym: "Bcl2-L-7 (human)" EXACT [UniProtKB:Q16611]
synonym: "Bcl-2-like protein 7 (human)" EXACT [UniProtKB:Q16611]
synonym: "apoptosis regulator BAK (human)" EXACT [UniProtKB:Q16611]
xref: Reactome:R-HSA-139896 "PR:Q16611 located_in GO:0005741"
xref: Reactome:R-HSA-50690 "PR:Q16611 located_in GO:0005741"
xref: UniProtKB:Q16611
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002185 ! Bcl-2 homologous antagonist/killer
relationship: has_gene_template HGNC:949 ! BAK1 (human)

[Term]
id: PR:Q16611-1
name: Bcl-2 homologous antagonist/killer isoform 1 (human)
def: "A Bcl-2 homologous antagonist/killer isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hBAK1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16611-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002262 ! Bcl-2 homologous antagonist/killer isoform 1