[Term]
id: PR:O15519-8
name: CASP8 and FADD-like apoptosis regulator isoform h8 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-8." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h8" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLAME-1 alpha (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-8
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-9
name: CASP8 and FADD-like apoptosis regulator isoform h9 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-9." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h9" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLAME-1 beta (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-9
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-1
name: CASP8 and FADD-like apoptosis regulator isoform h1 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-1." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CLARP1 (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLIP-L (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform I-FLICE 1 (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CASH alpha (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform MRIT alpha-1 (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLAME-1 gamma (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform Usurpin alpha (human)" EXACT [UniProtKB:O15519]
xref: Reactome:R-HSA-3371356 "PR:O15519-1 located_in GO:0005829"
xref: UniProtKB:O15519-1
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-2
name: CASP8 and FADD-like apoptosis regulator isoform h2 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-2." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CLARP2 (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLIP-S (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CASH beta (human)" EXACT [UniProtKB:O15519]
synonym: "CASP8 and FADD-like apoptosis regulator isoform MRIT beta-1 (human)" EXACT [UniProtKB:O15519]
xref: Reactome:R-HSA-3465357 "PR:O15519-2 located_in GO:0005829"
xref: UniProtKB:O15519-2
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-3
name: CASP8 and FADD-like apoptosis regulator isoform h3 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-3." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform MRIT alpha-2 (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-3
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-4
name: CASP8 and FADD-like apoptosis regulator isoform h4 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-4." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform I-FLICE 2 (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-4
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-5
name: CASP8 and FADD-like apoptosis regulator isoform h5 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-5." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform I-FLICE 3 (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-5
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-6
name: CASP8 and FADD-like apoptosis regulator isoform h6 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-6." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform I-FLICE 4 (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-6
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-7
name: CASP8 and FADD-like apoptosis regulator isoform h7 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-7." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform I-FLICE 5 (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-7
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-14
name: CASP8 and FADD-like apoptosis regulator isoform h14 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-14." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h14" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15519-14
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-12
name: CASP8 and FADD-like apoptosis regulator isoform h12 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-12." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h12" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform Usurpin gamma (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-12
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-13
name: CASP8 and FADD-like apoptosis regulator isoform h13 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-13." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h13" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15519-13
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-10
name: CASP8 and FADD-like apoptosis regulator isoform h10 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-10." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h10" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLAME-1 delta (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-10
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519-11
name: CASP8 and FADD-like apoptosis regulator isoform h11 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-11." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h11" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform Usurpin beta (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519-11
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15519
name: CASP8 and FADD-like apoptosis regulator (human)
def: "A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of human." [PRO:WCB, UniProtKB:O15519]
comment: Category=organism-gene.
synonym: "CASH" RELATED Gene-based [UniProtKB:O15519]
synonym: "MRIT" RELATED Gene-based [UniProtKB:O15519]
synonym: "CFLAR" RELATED Gene-based [UniProtKB:O15519]
synonym: "CLARP" RELATED Gene-based [UniProtKB:O15519]
synonym: "hCFLAR" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8AP1" RELATED Gene-based [UniProtKB:O15519]
synonym: "c-FLIP (human)" EXACT [UniProtKB:O15519]
synonym: "casper (human)" EXACT [UniProtKB:O15519]
synonym: "FLAME-1 (human)" EXACT [UniProtKB:O15519]
synonym: "I-FLICE (human)" EXACT [UniProtKB:O15519]
synonym: "usurpin (human)" EXACT [UniProtKB:O15519]
synonym: "caspase homolog (human)" EXACT [UniProtKB:O15519]
synonym: "inhibitor of FLICE (human)" EXACT [UniProtKB:O15519]
synonym: "caspase-eight-related protein (human)" EXACT [UniProtKB:O15519]
synonym: "MACH-related inducer of toxicity (human)" EXACT [UniProtKB:O15519]
synonym: "FADD-like antiapoptotic molecule 1 (human)" EXACT [UniProtKB:O15519]
synonym: "cellular FLICE-like inhibitory protein (human)" EXACT [UniProtKB:O15519]
synonym: "caspase-like apoptosis regulatory protein (human)" EXACT [UniProtKB:O15519]
xref: UniProtKB:O15519
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002282 ! CASP8 and FADD-like apoptosis regulator
relationship: has_gene_template HGNC:1876 ! CFLAR (human)

[Term]
id: PR:000002282
name: CASP8 and FADD-like apoptosis regulator
def: "A caspase-8-like protease that is a translation product of the human CFLAR gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "CASH" RELATED Gene-based []
synonym: "MRIT" RELATED Gene-based []
synonym: "CFLAR" EXACT PRO-short-label [PRO:DNx]
synonym: "CLARP" RELATED Gene-based []
synonym: "c-FLIP" EXACT []
synonym: "casper" EXACT []
synonym: "FLAME-1" EXACT []
synonym: "I-FLICE" EXACT []
synonym: "usurpin" EXACT []
synonym: "CASP8AP1" RELATED Gene-based []
synonym: "caspase homolog" EXACT []
synonym: "inhibitor of FLICE" EXACT []
synonym: "caspase-eight-related protein" EXACT []
synonym: "MACH-related inducer of toxicity" EXACT []
synonym: "FADD-like antiapoptotic molecule 1" EXACT []
synonym: "cellular FLICE-like inhibitory protein" EXACT []
synonym: "caspase-like apoptosis regulatory protein" EXACT []
is_a: PR:000002197 ! caspase-8-like protease

[Term]
id: PR:O15519-15
name: CASP8 and FADD-like apoptosis regulator isoform h15 (human)
def: "A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-15." [PRO:DNx, UniProtKB:O15519]
comment: Category=organism-sequence.
synonym: "hCFLAR/iso:h15" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15519-15
is_a: PR:O15519 ! CASP8 and FADD-like apoptosis regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens