[Term]
id: PR:P55211-2
name: caspase-9 isoform 2 (human)
def: "A caspase-9 isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hCASP9/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-9 isoform 9S (human)" EXACT [UniProtKB:P55211]
synonym: "caspase-9 isoform Beta (human)" EXACT [UniProtKB:P55211]
xref: UniProtKB:P55211-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002422 ! caspase-9 isoform 2

[Term]
id: PR:P55211-3
name: caspase-9 isoform h3 (human)
def: "A caspase-9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-3." [PRO:DNx, UniProtKB:P55211]
comment: Category=organism-sequence.
synonym: "hCASP9/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-9 isoform Gamma (human)" EXACT [UniProtKB:P55211]
xref: UniProtKB:P55211-3
is_a: PR:P55211 ! caspase-9 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55211
name: caspase-9 (human)
def: "A caspase-9 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P55211]
comment: Category=organism-gene.
synonym: "MCH6" RELATED Gene-based [UniProtKB:P55211]
synonym: "CASP9" RELATED Gene-based [UniProtKB:P55211]
synonym: "hCASP9" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-3 (human)" EXACT [UniProtKB:P55211]
synonym: "CASP-9 (human)" EXACT [UniProtKB:P55211]
synonym: "ICE-LAP6 (human)" EXACT [UniProtKB:P55211]
synonym: "apoptotic protease Mch-6 (human)" EXACT [UniProtKB:P55211]
synonym: "ICE-like apoptotic protease 6 (human)" EXACT [UniProtKB:P55211]
synonym: "apoptotic protease-activating factor 3 (human)" EXACT [UniProtKB:P55211]
xref: Reactome:R-HSA-114257 "PR:P55211 located_in GO:0005829"
xref: Reactome:R-HSA-57033 "PR:P55211 located_in GO:0005829"
xref: UniProtKB:P55211
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002318 ! caspase-9
relationship: has_gene_template HGNC:1511 ! CASP9 (human)

[Term]
id: PR:P55211-4
name: caspase-9 isoform h4 (human)
def: "A caspase-9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-4." [PRO:DNx, UniProtKB:P55211]
comment: Category=organism-sequence.
synonym: "hCASP9/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55211-4
is_a: PR:P55211 ! caspase-9 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045839
name: caspase-9 phosphorylated 1 (human)
def: "A caspase-9 (human) that has been phosphorylated on the residue at the position equivalent to Thr-125 of the amino acid sequence represented by UniProtKB:P55211-1. Example: UniProtKB:P55211-1, Thr-125, MOD:00047." [PMID:12792650, PMID:17466630, iPTMnet:P55211]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12792650, PMID:17466630). Status=unreviewed.
synonym: "hCASP9/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P55211-1, Thr-125, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P55211 ! caspase-9 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002318
name: caspase-9
def: "A caspase-1-like protease that is a translation product of the human CASP9 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "MCH6" RELATED Gene-based []
synonym: "CASP9" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-3" EXACT []
synonym: "CASP-9" EXACT []
synonym: "ICE-LAP6" EXACT []
synonym: "apoptotic protease Mch-6" EXACT []
synonym: "ICE-like apoptotic protease 6" EXACT []
synonym: "apoptotic protease-activating factor 3" EXACT []
xref: IUPHARobj:1625
is_a: PR:000002195 ! caspase-1-like protease

[Term]
id: PR:000046571
name: caspase-9 phosphorylated 2 (human)
def: "A caspase-9 (human) that has been phosphorylated on the residue at the position equivalent to Ser-196 of the amino acid sequence represented by UniProtKB:P55211. UniProtKB:P55211, Ser-196, MOD:00046." [PRO:DNx, Reactome:R-HSA-198636]
comment: Category=organism-modification.
synonym: "hCASP9/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P55211, Ser-196, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-198636 "PR:000046571 located_in GO:0005829"
is_a: PR:P55211 ! caspase-9 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55211-1
name: caspase-9 isoform 1 (human)
def: "A caspase-9 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hCASP9/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-9 isoform 9L (human)" EXACT [UniProtKB:P55211]
synonym: "caspase-9 isoform Alpha (human)" EXACT [UniProtKB:P55211]
xref: UniProtKB:P55211-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002421 ! caspase-9 isoform 1

[Term]
id: PR:000050096
name: caspase-9 subunit p10 (human)
def: "A caspase-9 subunit p10 in human. Example: UniProtKB:P55211-1, 331-416." [PRO:DNx, UniProtKB:P55211]
comment: Category=organism-modification.
synonym: "hCASP9/p10" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000004643" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P55211-1, 331-416" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000050090 ! caspase-9 subunit p10

[Term]
id: PR:000050095
name: caspase-9 subunit p35 (human)
def: "A caspase-9 subunit p35 in human. Example: UniProtKB:P55211-1, ?-315." [PRO:DNx, UniProtKB:P55211]
comment: Category=organism-modification.
synonym: "hCASP9/p35" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000004641" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P55211-1, ?-315" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000050089 ! caspase-9 subunit p35