[Term]
id: PR:000003020
name: merlin
def: "An erm protein that is a translation product of the human NF2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "NF2" EXACT PRO-short-label [PRO:DNx]
synonym: "SCH" RELATED Gene-based []
synonym: "Nf-2" RELATED Gene-based []
synonym: "schwannomin" EXACT []
synonym: "schwannomerlin" EXACT []
synonym: "neurofibromin-2" EXACT []
synonym: "moesin-ezrin-radixin-like protein" EXACT []
is_a: PR:000001030 ! erm protein

[Term]
id: PR:P35240-8
name: merlin isoform h8 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-8." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h8" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35240-8
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35240
name: merlin (human)
def: "A merlin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P35240]
comment: Category=organism-gene.
synonym: "NF2" RELATED Gene-based [UniProtKB:P35240]
synonym: "SCH" RELATED Gene-based [UniProtKB:P35240]
synonym: "hNF2" EXACT PRO-short-label [PRO:DNx]
synonym: "schwannomin (human)" EXACT [UniProtKB:P35240]
synonym: "schwannomerlin (human)" EXACT [UniProtKB:P35240]
synonym: "neurofibromin-2 (human)" EXACT [UniProtKB:P35240]
synonym: "moesin-ezrin-radixin-like protein (human)" EXACT [UniProtKB:P35240]
xref: Reactome:R-HSA-5669168 "PR:P35240 located_in GO:0005886"
xref: UniProtKB:P35240
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003020 ! merlin
relationship: has_gene_template HGNC:7773 ! NF2 (human)

[Term]
id: PR:P35240-6
name: merlin isoform h6 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-6." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform delE2 (human)" EXACT [UniProtKB:P35240]
xref: UniProtKB:P35240-6
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35240-7
name: merlin isoform h7 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-7." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform MER150 (human)" EXACT [UniProtKB:P35240]
xref: UniProtKB:P35240-7
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35240-4
name: merlin isoform 4 (human)
def: "A merlin isoform 4 that is encoded in the genome of human." [PMID:10669747, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hNF2/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin delE2/3 (human)" EXACT []
xref: UniProtKB:P35240-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026547 ! merlin isoform 4

[Term]
id: PR:P35240-5
name: merlin isoform h5 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-5." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform delE3 (human)" EXACT [UniProtKB:P35240]
xref: UniProtKB:P35240-5
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35240-2
name: merlin isoform 3 (human)
def: "A merlin isoform 3 that is encoded in the genome of human." [PMID:15467741, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hNF2/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35240-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026545 ! merlin isoform 3

[Term]
id: PR:P35240-3
name: merlin isoform 2 (human)
def: "A merlin isoform 2 that is encoded in the genome of human." [PMID:15467741, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hNF2/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform II (human)" EXACT [PRO:DNx]
xref: UniProtKB:P35240-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003022 ! merlin isoform 2

[Term]
id: PR:P35240-1
name: merlin isoform 1 (human)
def: "A merlin isoform 1 that is encoded in the genome of human." [PMID:9430655, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hNF2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35240-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003021 ! merlin isoform 1

[Term]
id: PR:P35240-10
name: merlin isoform h10 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-10." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h10" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform MER151 (human)" EXACT [UniProtKB:P35240]
xref: UniProtKB:P35240-10
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35240-9
name: merlin isoform h9 (human)
def: "A merlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-9." [PRO:DNx, UniProtKB:P35240]
comment: Category=organism-sequence.
synonym: "hNF2/iso:h9" EXACT PRO-short-label [PRO:DNx]
synonym: "merlin isoform MER162 (human)" EXACT [UniProtKB:P35240]
xref: UniProtKB:P35240-9
is_a: PR:P35240 ! merlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045760
name: merlin phosphorylated 1 (human)
def: "A merlin (human) that has been phosphorylated on the residue at the position equivalent to Ser-518 of the amino acid sequence represented by UniProtKB:P35240-1. Example: UniProtKB:P35240-1, Ser-518, MOD:00046." [PMID:11719502, PMID:11782491, PMID:14981079, PMID:15378014, PMID:17566081, iPTMnet:P35240]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11719502, PMID:11782491, PMID:14981079, PMID:15378014, PMID:17566081). Status=unreviewed.
synonym: "hNF2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35240-1, Ser-518, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35240 ! merlin (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens