[Term]
id: PR:000003031
name: focal adhesion kinase 1
def: "A focal adhesion kinase that is a translation product of the human PTK2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "FAK" RELATED Gene-based []
synonym: "FAK1" RELATED Gene-based []
synonym: "FRNK" EXACT []
synonym: "Fadk" RELATED Gene-based []
synonym: "PTK2" EXACT PRO-short-label [PRO:DNx]
synonym: "FADK 1" EXACT []
synonym: "p125FAK" EXACT []
synonym: "Kiaa4203" RELATED Gene-based []
synonym: "pp125FAK" EXACT []
synonym: "protein-tyrosine kinase 2" EXACT []
synonym: "focal adhesion kinase-related nonkinase" EXACT []
xref: IUPHARobj:2180
is_a: PR:000003030 ! focal adhesion kinase

[Term]
id: PR:O35346-1
name: focal adhesion kinase 1 isoform 1 (rat)
def: "A focal adhesion kinase 1 isoform 4 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPTK2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35346-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039313 ! focal adhesion kinase 1 isoform 4

[Term]
id: PR:O35346-2
name: focal adhesion kinase 1 isoform r2 (rat)
def: "A focal adhesion kinase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35346-2." [PRO:DNx, UniProtKB:O35346]
comment: Category=organism-sequence.
synonym: "rPTK2/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "focal adhesion kinase 1 isoform FRNK (rat)" EXACT [UniProtKB:O35346]
xref: UniProtKB:O35346-2
is_a: PR:O35346 ! focal adhesion kinase 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O35346
name: focal adhesion kinase 1 (rat)
def: "A focal adhesion kinase 1 that is encoded in the genome of rat." [OMA:O35346, PANTHER:PTHR24418:SF277, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fak" RELATED Gene-based [UniProtKB:O35346]
synonym: "Fak1" RELATED Gene-based [UniProtKB:O35346]
synonym: "Ptk2" RELATED Gene-based [UniProtKB:O35346]
synonym: "rPTK2" EXACT PRO-short-label [PRO:DNx]
synonym: "FRNK (rat)" EXACT [UniProtKB:O35346]
synonym: "FADK 1 (rat)" EXACT [UniProtKB:O35346]
synonym: "p125FAK (rat)" EXACT [UniProtKB:O35346]
synonym: "pp125FAK (rat)" EXACT [UniProtKB:O35346]
synonym: "protein-tyrosine kinase 2 (rat)" EXACT [UniProtKB:O35346]
synonym: "focal adhesion kinase-related nonkinase (rat)" EXACT [UniProtKB:O35346]
xref: UniProtKB:O35346
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003031 ! focal adhesion kinase 1
relationship: has_gene_template RGD:3443 ! Ptk2 (rat)

[Term]
id: PR:000049948
name: focal adhesion kinase 1 isoform 1 phosphorylated 2 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, MOD:00048." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-576/Tyr-577, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000049949
name: focal adhesion kinase 1 isoform 1 unphosphorylated 2 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, PR:000026291." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/UnPhos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-576/Tyr-577, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000049951
name: focal adhesion kinase 1 isoform 1 unphosphorylated 3 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, PR:000026291." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/UnPhos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-928, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000049950
name: focal adhesion kinase 1 isoform 1 phosphorylated 3 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, MOD:00048." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-928, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000049946
name: focal adhesion kinase 1 isoform 1 phosphorylated 1 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, MOD:00048." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-397, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000049947
name: focal adhesion kinase 1 isoform 1 unphosphorylated 1 (rat)
def: "A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, PR:000026291." [PMID:27994061, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27994061).
synonym: "rPTK2/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O35346-1, Tyr-397, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O35346-1 ! focal adhesion kinase 1 isoform 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus