[Term] id: PR:Q95Q95-1 name: target of rapamycin homolog isoform a (worm) def: "A target of rapamycin homolog (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q95Q95-1." [PRO:DNx, UniProtKB:Q95Q95] comment: Category=organism-sequence. synonym: "MTOR/iso:a (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q95Q95-1 is_a: PR:Q95Q95 ! target of rapamycin homolog (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:000003041 name: serine/threonine-protein kinase mTOR def: "A protein that is a translation product of the human MTOR gene or a 1:1 ortholog thereof." [PRO:CL] comment: Category=gene. synonym: "FRAP" RELATED Gene-based [] synonym: "MTOR" EXACT PRO-short-label [PRO:DNx] synonym: "mTOR" EXACT [] synonym: "FRAP1" RELATED Gene-based [] synonym: "FRAP2" RELATED Gene-based [] synonym: "RAFT1" RELATED Gene-based [] synonym: "RAPT1" RELATED Gene-based [] synonym: "rapamycin target protein 1" EXACT [] synonym: "mammalian target of rapamycin" EXACT [] synonym: "mechanistic target of rapamycin" EXACT [] synonym: "FKBP12-rapamycin complex-associated protein" EXACT [] synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1" EXACT [] xref: IUPHARobj:2109 is_a: PR:000000001 ! protein [Term] id: PR:Q9JLN9 name: serine/threonine-protein kinase mTOR (mouse) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of mouse." [OMA:Q9JLN9, PRO:DNx] comment: Category=organism-gene. synonym: "Frap" RELATED Gene-based [UniProtKB:Q9JLN9] synonym: "Mtor" RELATED Gene-based [UniProtKB:Q9JLN9] synonym: "Frap1" RELATED Gene-based [UniProtKB:Q9JLN9] synonym: "mMTOR" EXACT PRO-short-label [PRO:DNx] synonym: "RAPT1 (mouse)" EXACT [UniProtKB:Q9JLN9] synonym: "rapamycin target protein 1 (mouse)" EXACT [UniProtKB:Q9JLN9] synonym: "mammalian target of rapamycin (mouse)" EXACT [UniProtKB:Q9JLN9] synonym: "mechanistic target of rapamycin (mouse)" EXACT [UniProtKB:Q9JLN9] synonym: "FKBP12-rapamycin complex-associated protein (mouse)" EXACT [UniProtKB:Q9JLN9] synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1 (mouse)" EXACT [UniProtKB:Q9JLN9] xref: UniProtKB:Q9JLN9 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template MGI:1928394 ! Mtor (mouse) [Term] id: PR:P42346-1 name: serine/threonine-protein kinase mTOR isoform 1 (rat) def: "A serine/threonine-protein kinase mTOR isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rMTOR/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P42346-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039438 ! serine/threonine-protein kinase mTOR isoform 1 [Term] id: PR:000045781 name: serine/threonine-protein kinase mTOR phosphorylated 1 (human) def: "A serine/threonine-protein kinase mTOR (human) that has been phosphorylated at Ser-2481. UniProtKB:P42345, Ser-2481, MOD:00046." [PMID:10702316, iPTMnet:P42345] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10702316). Status=unreviewed. synonym: "hMTOR/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P42345, Ser-2481, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P42345 ! serine/threonine-protein kinase mTOR (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q95Q95-2 name: target of rapamycin homolog isoform b (worm) def: "A target of rapamycin homolog (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q95Q95-2." [PRO:DNx, UniProtKB:Q95Q95] comment: Category=organism-sequence. synonym: "MTOR/iso:b (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q95Q95-2 is_a: PR:Q95Q95 ! target of rapamycin homolog (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:P42345-1 name: serine/threonine-protein kinase mTOR isoform 1 (human) def: "A serine/threonine-protein kinase mTOR isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hMTOR/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P42345-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039438 ! serine/threonine-protein kinase mTOR isoform 1 [Term] id: PR:Q95Q95 name: target of rapamycin homolog (worm) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of worm." [OMA:Q95Q95, PANTHER:PTHR11139:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "CeTOR" EXACT [UniProtKB:Q95Q95] synonym: "CeTor" RELATED Gene-based [UniProtKB:Q95Q95] synonym: "B0261.2" RELATED Gene-based [UniProtKB:Q95Q95] synonym: "let-363" RELATED Gene-based [UniProtKB:Q95Q95] synonym: "MTOR (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "lethal protein 363 (worm)" EXACT [UniProtKB:Q95Q95] xref: UniProtKB:Q95Q95 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template WormBase:WBGene00002583 ! let-363 (worm) [Term] id: PR:Q86C65 name: serine/threonine-protein kinase tor (Dictyostelium discoideum) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of Dictyostelium discoideum." [OMA:Q86C65, PANTHER:PTHR11139:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "tor" RELATED Gene-based [UniProtKB:Q86C65] synonym: "Dicty-MTOR" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0281569" RELATED Gene-based [UniProtKB:Q86C65] synonym: "target of rapamycin (Dictyostelium discoideum)" EXACT [UniProtKB:Q86C65] xref: UniProtKB:Q86C65 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template dictyBase:DDB_G0281569 ! tor (Dictyostelium discoideum) [Term] id: PR:P42345 name: serine/threonine-protein kinase mTOR (human) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of human." [PRO:CL, UniProtKB:P42345] comment: Category=organism-gene. synonym: "FRAP" RELATED Gene-based [UniProtKB:P42345] synonym: "MTOR" RELATED Gene-based [UniProtKB:P42345] synonym: "FRAP1" RELATED Gene-based [UniProtKB:P42345] synonym: "FRAP2" RELATED Gene-based [UniProtKB:P42345] synonym: "RAFT1" RELATED Gene-based [UniProtKB:P42345] synonym: "RAPT1" RELATED Gene-based [UniProtKB:P42345] synonym: "hMTOR" EXACT PRO-short-label [PRO:DNx] synonym: "mTOR (human)" EXACT [UniProtKB:P42345] synonym: "rapamycin target protein 1 (human)" EXACT [UniProtKB:P42345] synonym: "mammalian target of rapamycin (human)" EXACT [UniProtKB:P42345] synonym: "rapamycin and FKBP12 target 1 (human)" EXACT [UniProtKB:P42345] synonym: "mechanistic target of rapamycin (human)" EXACT [UniProtKB:P42345] synonym: "FKBP12-rapamycin complex-associated protein (human)" EXACT [UniProtKB:P42345] synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1 (human)" EXACT [UniProtKB:P42345] xref: Reactome:R-HSA-165662 "PR:P42345 located_in GO:0005829" xref: Reactome:R-HSA-5083674 "PR:P42345 located_in GO:0005654" xref: DTO:03100345 xref: UniProtKB:P42345 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template HGNC:3942 ! MTOR (human) [Term] id: PR:P42346 name: serine/threonine-protein kinase mTOR (rat) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of rat." [OMA:P42346, PANTHER:PTHR11139:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "Mtor" RELATED Gene-based [UniProtKB:P42346] synonym: "Frap1" RELATED Gene-based [UniProtKB:P42346] synonym: "Raft1" RELATED Gene-based [UniProtKB:P42346] synonym: "rMTOR" EXACT PRO-short-label [PRO:DNx] synonym: "mTOR (rat)" EXACT [UniProtKB:P42346] synonym: "RAPT1 (rat)" EXACT [UniProtKB:P42346] synonym: "rapamycin target protein 1 (rat)" EXACT [UniProtKB:P42346] synonym: "mammalian target of rapamycin (rat)" EXACT [UniProtKB:P42346] synonym: "mechanistic target of rapamycin (rat)" EXACT [UniProtKB:P42346] synonym: "FKBP12-rapamycin complex-associated protein (rat)" EXACT [UniProtKB:P42346] synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1 (rat)" EXACT [UniProtKB:P42346] xref: UniProtKB:P42346 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template RGD:68371 ! Mtor (rat) [Term] id: PR:Q9FR53 name: serine/threonine-protein kinase TOR (Arabidopsis thaliana) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FR53, PRO:DNx] comment: Category=organism-gene. synonym: "TOR" RELATED Gene-based [UniProtKB:Q9FR53] synonym: "AtTOR" RELATED Gene-based [UniProtKB:Q9FR53] synonym: "At-MTOR" EXACT PRO-short-label [PRO:DNx] synonym: "F2J10.19" RELATED Gene-based [UniProtKB:Q9FR53] synonym: "At1g50030" RELATED Gene-based [UniProtKB:Q9FR53] synonym: "protein TARGET OF RAPAMYCIN (Arabidopsis thaliana)" EXACT [UniProtKB:Q9FR53] xref: UniProtKB:Q9FR53 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template Araport:AT1G50030 ! TOR (Arabidopsis thaliana) [Term] id: PR:Q9JLN9-2 name: serine/threonine-protein kinase mTOR isoform m2 (mouse) def: "A serine/threonine-protein kinase mTOR (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JLN9-2." [PRO:DNx, UniProtKB:Q9JLN9] comment: Category=organism-sequence. synonym: "mMTOR/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JLN9-2 is_a: PR:Q9JLN9 ! serine/threonine-protein kinase mTOR (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9JLN9-1 name: serine/threonine-protein kinase mTOR isoform 1 (mouse) def: "A serine/threonine-protein kinase mTOR isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mMTOR/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JLN9-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039438 ! serine/threonine-protein kinase mTOR isoform 1 [Term] id: PR:Q9VK45 name: serine/threonine-protein kinase Tor (fruit fly) def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of fruit fly." [OMA:Q9VK45, PANTHER:PTHR11139:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "Tor" RELATED Gene-based [UniProtKB:Q9VK45] synonym: "CG5092" RELATED Gene-based [UniProtKB:Q9VK45] synonym: "fly-MTOR" EXACT PRO-short-label [PRO:DNx] synonym: "target of rapamycin (fruit fly)" EXACT [UniProtKB:Q9VK45] xref: UniProtKB:Q9VK45 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR relationship: has_gene_template FlyBase:FBgn0021796 ! Tor (fruit fly) [Term] id: PR:000039438 name: serine/threonine-protein kinase mTOR isoform 1 def: "A serine/threonine-protein kinase mTOR that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42345-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "MTOR/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003041 ! serine/threonine-protein kinase mTOR [Term] id: PR:Q9FR53-1 name: serine/threonine-protein kinase TOR isoform 1 (Arabidopsis thaliana) def: "A serine/threonine-protein kinase TOR (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9FR53-1." [PRO:DNx, UniProtKB:Q9FR53] comment: Category=organism-sequence. synonym: "At-MTOR/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9FR53-1 is_a: PR:Q9FR53 ! serine/threonine-protein kinase TOR (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana