[Term]
id: PR:000025834
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 phosphorylated 1 in mouse. UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048." [PMID:15536084, PRO:JAN]
comment: Category=organism-modification.
synonym: "mSYK/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025833 ! tyrosine-protein kinase SYK isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000049800
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 6 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at positions 519 and 520, but it is still phosphorylated at Tyr 342 and 346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048|Tyr-519/Tyr-520, PR:000026291." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048|Tyr-519/Tyr-520, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000003065
name: tyrosine-protein kinase SYK
def: "A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human SYK gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SYK" EXACT PRO-short-label [PRO:DNx]
synonym: "spleen tyrosine kinase" EXACT []
xref: IUPHARobj:2230
is_a: PR:000003063 ! SYK/ZAP-70 family tyrosine-protein kinase

[Term]
id: PR:P48025
name: tyrosine-protein kinase SYK (mouse)
def: "A tyrosine-protein kinase SYK that is encoded in the genome of mouse." [OMA:P48025, PRO:DNx]
comment: Category=organism-gene.
synonym: "Syk" RELATED Gene-based [UniProtKB:P48025]
synonym: "Sykb" RELATED Gene-based [UniProtKB:P48025]
synonym: "mSYK" EXACT PRO-short-label [PRO:DNx]
synonym: "ptk72" RELATED Gene-based [UniProtKB:P48025]
synonym: "spleen tyrosine kinase (mouse)" EXACT [UniProtKB:P48025]
xref: UniProtKB:P48025
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003065 ! tyrosine-protein kinase SYK
relationship: has_gene_template MGI:99515 ! Syk (mouse)

[Term]
id: PR:P48025-1
name: tyrosine-protein kinase SYK isoform 1 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mSYK/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48025-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025832 ! tyrosine-protein kinase SYK isoform 1

[Term]
id: PR:000049793
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 3 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-346. UniProtKB:P48025-1, Tyr-346, MOD:00048." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "mSYK long isoform Y346 phosphorylated" EXACT []
synonym: "UniProtKB:P48025-1, Tyr-346, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049792
name: tyrosine-protein kinase SYK isoform 1 unphosphorylated 2 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 342. UniProtKB:P48025-1, Tyr-342, PR:000026291." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/UnPhos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48025-1, Tyr-342, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049791
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 2 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342. UniProtKB:P48025-1, Tyr-342, MOD:00048." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "mSYK long isoform Y342 phosphorylated" EXACT []
synonym: "UniProtKB:P48025-1, Tyr-342, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049796
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 5 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342, Tyr-346, Tyr-519 and Tyr-520. UniProtKB:P48025-1, Tyr-342/Tyr-346/Tyr-519/Tyr-520, MOD:00048." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "mSYK long isoform Y342/Y346/Y519/Y520 phosphorylated" EXACT []
synonym: "UniProtKB:P48025-1, Tyr-342/Tyr-346/Tyr-519/Tyr-520, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049795
name: tyrosine-protein kinase SYK isoform 1 phosphorylated 4 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342 and Tyr-346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517).
synonym: "mSYK/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "mSYK long isoform Y342/Y346 phosphorylated" EXACT []
synonym: "UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049794
name: tyrosine-protein kinase SYK isoform 1 unphosphorylated 3 (mouse)
def: "A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 346. UniProtKB:P48025-1, Tyr-346, PR:000026291." [PMID:27609517, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27609517). Note: Dephosphorylated by Ubash3b (Tula-2).
synonym: "mSYK/iso:1/UnPhos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48025-1, Tyr-346, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P48025-1 ! tyrosine-protein kinase SYK isoform 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus