[Term] id: PR:P98170 name: E3 ubiquitin-protein ligase XIAP (human) def: "A baculoviral IAP repeat-containing protein 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P98170] comment: Category=organism-gene. synonym: "API3" RELATED Gene-based [UniProtKB:P98170] synonym: "IAP3" RELATED Gene-based [UniProtKB:P98170] synonym: "XIAP" RELATED Gene-based [UniProtKB:P98170] synonym: "hILP" EXACT [UniProtKB:P98170] synonym: "BIRC4" RELATED Gene-based [UniProtKB:P98170] synonym: "hIAP3" EXACT [UniProtKB:P98170] synonym: "hXIAP" EXACT PRO-short-label [PRO:DNx] synonym: "hIAP-3" EXACT [UniProtKB:P98170] synonym: "ILP (human)" EXACT [UniProtKB:P98170] synonym: "IAP-3 (human)" EXACT [UniProtKB:P98170] synonym: "X-linked IAP (human)" EXACT [UniProtKB:P98170] synonym: "IAP-like protein (human)" EXACT [UniProtKB:P98170] synonym: "inhibitor of apoptosis protein 3 (human)" EXACT [UniProtKB:P98170] synonym: "RING-type E3 ubiquitin transferase XIAP (human)" EXACT [UniProtKB:P98170] synonym: "X-linked inhibitor of apoptosis protein (human)" EXACT [UniProtKB:P98170] synonym: "baculoviral IAP repeat-containing protein 4 (human)" EXACT [UniProtKB:P98170] xref: Reactome:R-HSA-50849 "PR:P98170 located_in GO:0005829" xref: Reactome:R-HSA-3322366 "PR:P98170 located_in GO:0005654" xref: UniProtKB:P98170 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003119 ! baculoviral IAP repeat-containing protein 4 relationship: has_gene_template HGNC:592 ! XIAP (human) [Term] id: PR:P98170-1 name: E3 ubiquitin-protein ligase XIAP isoform 1 (human) def: "A baculoviral IAP repeat-containing protein 4 isoform 1 that is encoded in the genome of human." [PRO:JAN] comment: Category=organism-sequence. synonym: "hXIAP/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P98170-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003120 ! baculoviral IAP repeat-containing protein 4 isoform 1 [Term] id: PR:000003119 name: baculoviral IAP repeat-containing protein 4 def: "A protein that is a translation product of the human XIAP gene or a 1:1 ortholog thereof. Potent negative regulator of apoptosis." [PRO:CNA] comment: Category=gene. synonym: "ILP" EXACT [] synonym: "API3" RELATED Gene-based [] synonym: "Aipa" RELATED Gene-based [] synonym: "IAP3" RELATED Gene-based [] synonym: "Miha" RELATED Gene-based [] synonym: "XIAP" EXACT PRO-short-label [PRO:DNx] synonym: "BIRC4" RELATED Gene-based [] synonym: "IAP-3" EXACT [] synonym: "X-linked IAP" EXACT [] synonym: "IAP homolog A" EXACT [] synonym: "IAP-like protein" EXACT [] synonym: "E3 ubiquitin-protein ligase XIAP" EXACT [] synonym: "inhibitor of apoptosis protein 3" EXACT [] synonym: "RING-type E3 ubiquitin transferase XIAP" EXACT [] synonym: "X-linked inhibitor of apoptosis protein" EXACT [] xref: IUPHARobj:2790 is_a: PR:000000001 ! protein [Term] id: PR:000049706 name: E3 ubiquitin-protein ligase XIAP ubiquitinated form (human) def: "An E3 ubiquitin-protein ligase XIAP (human) that includes at least one ubiquitinated lysine. UniProtKB:P98170, MOD:01148." [PRO:DNx, Reactome:R-HSA-5675477] comment: Category=organism-modification. synonym: "hXIAP/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P98170, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5675477 "PR:000049706 located_in GO:0005829" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: PR:P98170 ! E3 ubiquitin-protein ligase XIAP (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens