[Term]
id: PR:000046969
name: collagen alpha-2(VI) chain, signal peptide removed 4-hydroxy-proline form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed and that includes at least one 4-hydroxy-proline. UniProtKB:P12110, 21-1019, MOD:00039." [PRO:DNx, Reactome:R-HSA-2022423, Reactome:R-HSA-2127477]
comment: Category=organism-modification.
synonym: "hCOL6A2/SigPep-/4HyPro+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005832, MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022423 "PR:000046969 located_in GO:0005788"
xref: Reactome:R-HSA-2127477 "PR:000046969 located_in GO:0005576"
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046968
name: collagen alpha-2(VI) chain, signal peptide removed 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed and that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P12110, 21-1019, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022438, Reactome:R-HSA-2127495]
comment: Category=organism-modification.
synonym: "hCOL6A2/SigPep-/3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005832, MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022438 "PR:000046968 located_in GO:0005788"
xref: Reactome:R-HSA-2127495 "PR:000046968 located_in GO:0005576"
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12110-3
name: collagen alpha-2(VI) chain isoform h2C2A' (human)
def: "A collagen alpha-2(VI) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12110-3." [PRO:DNx, UniProtKB:P12110]
comment: Category=organism-sequence.
synonym: "hCOL6A2/iso:h2C2A'" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12110-3
is_a: PR:P12110 ! collagen alpha-2(VI) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12110-1
name: collagen alpha-2(VI) chain isoform 2C2 (human)
def: "A collagen alpha-2(VI) chain isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOL6A2/iso:2C2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12110-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003358 ! collagen alpha-2(VI) chain isoform 1

[Term]
id: PR:Q02788
name: collagen alpha-2(VI) chain (mouse)
def: "A collagen alpha-2(VI) chain that is encoded in the genome of mouse." [OMA:Q02788, PRO:DNx]
comment: Category=organism-gene.
synonym: "Col6a2" RELATED Gene-based [UniProtKB:Q02788]
synonym: "mCOL6A2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02788
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003357 ! collagen alpha-2(VI) chain
relationship: has_gene_template MGI:88460 ! Col6a2 (mouse)

[Term]
id: PR:P15988-1
name: collagen alpha-2(VI) chain isoform 1 (chicken)
def: "A collagen alpha-2(VI) chain (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15988-1." [PRO:DNx, UniProtKB:P15988]
comment: Category=organism-sequence.
synonym: "chick-COL6A2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15988-1
is_a: PR:P15988 ! collagen alpha-2(VI) chain (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:000003357
name: collagen alpha-2(VI) chain
def: "A collagen type VI alpha chain that is a translation product of the human COL6A2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "COL6A2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003386 ! collagen type VI alpha chain

[Term]
id: PR:P15988-2
name: collagen alpha-2(VI) chain isoform 2 (chicken)
def: "A collagen alpha-2(VI) chain (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15988-2." [PRO:DNx, UniProtKB:P15988]
comment: Category=organism-sequence.
synonym: "chick-COL6A2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15988-2
is_a: PR:P15988 ! collagen alpha-2(VI) chain (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:000003360
name: collagen alpha-2(VI) chain isoform 1, signal peptide removed form
def: "A collagen alpha-2(VI) chain isoform 1 that has had the signal peptide removed to yield the mature protein. Example: UniProtKB:P12110-1, 21-1019." [PRO:CNA]
comment: Category=modification.
synonym: "COL6A2/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "collagen alpha-2(VI) chain mature" EXACT []
synonym: "collagen alpha-2(VI) chain isoform 1 cleaved 1" EXACT []
intersection_of: PR:000003358 ! collagen alpha-2(VI) chain isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000003358
name: collagen alpha-2(VI) chain isoform 1
def: "A collagen alpha-2(VI) chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12110-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "COL6A2/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "collagen alpha-2(VI) isoform 2C2" EXACT []
synonym: "collagen alpha-2(VI) chain isoform 2C2" EXACT []
is_a: PR:000003357 ! collagen alpha-2(VI) chain

[Term]
id: PR:000046972
name: collagen alpha-2(VI) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:P12110, 21-1019, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022975, Reactome:R-HSA-2127475]
comment: Category=organism-modification.
synonym: "hCOL6A2/SigPep-/5hL4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005832, MOD:00037|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022975 "PR:000046972 located_in GO:0005788"
xref: Reactome:R-HSA-2127475 "PR:000046972 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025422
name: collagen alpha-2(VI) chain proteolytic cleavage product
def: "A collagen alpha-2(VI) chain that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "COL6A2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003357 ! collagen alpha-2(VI) chain

[Term]
id: PR:000046967
name: collagen alpha-2(VI) chain, signal peptide removed form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed. UniProtKB:P12110, 21-1019." [PRO:DNx, Reactome:R-HSA-1614503, Reactome:R-HSA-2127536]
comment: Category=organism-modification.
synonym: "PRO_0000005832" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCOL6A2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2127536 "PR:000046967 located_in GO:0005576"
xref: Reactome:R-HSA-1614503 "PR:000046967 located_in GO:0005788"
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046971
name: collagen alpha-2(VI) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P12110, 21-1019, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022943, Reactome:R-HSA-2127498]
comment: Category=organism-modification.
synonym: "hCOL6A2/SigPep-/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005832, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022943 "PR:000046971 located_in GO:0005788"
xref: Reactome:R-HSA-2127498 "PR:000046971 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12110-2
name: collagen alpha-2(VI) chain isoform h2C2A (human)
def: "A collagen alpha-2(VI) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12110-2." [PRO:DNx, UniProtKB:P12110]
comment: Category=organism-sequence.
synonym: "hCOL6A2/iso:h2C2A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12110-2
is_a: PR:P12110 ! collagen alpha-2(VI) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046970
name: collagen alpha-2(VI) chain, signal peptide removed 5-hydroxy-lysine form (human)
def: "A collagen alpha-2(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine. UniProtKB:P12110, 21-1019, MOD:00037." [PRO:DNx, Reactome:R-HSA-2023007, Reactome:R-HSA-2127467]
comment: Category=organism-modification.
synonym: "hCOL6A2/SigPep-/5HyLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005832, MOD:00037" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12110, 21-1019, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2023007 "PR:000046970 located_in GO:0005788"
xref: Reactome:R-HSA-2127467 "PR:000046970 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: PR:P12110 ! collagen alpha-2(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12110
name: collagen alpha-2(VI) chain (human)
def: "A collagen alpha-2(VI) chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12110]
comment: Category=organism-gene.
synonym: "COL6A2" RELATED Gene-based [UniProtKB:P12110]
synonym: "hCOL6A2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12110
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003357 ! collagen alpha-2(VI) chain
relationship: has_gene_template HGNC:2212 ! COL6A2 (human)

[Term]
id: PR:P15988
name: collagen alpha-2(VI) chain (chicken)
def: "A collagen alpha-2(VI) chain that is encoded in the genome of chicken." [OMA:P15988, PANTHER:PTHR24023:SF67, PRO:DNx]
comment: Category=organism-gene.
synonym: "COL6A2" RELATED Gene-based [UniProtKB:P15988]
synonym: "chick-COL6A2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15988
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000003357 ! collagen alpha-2(VI) chain
relationship: has_gene_template NCBIGene:396292 ! COL6A2 (chicken)