[Term]
id: PR:000037802
name: ADAMTS-like protein 2, signal peptide removed form
def: "An ADAMTS-like protein 2 that has had the signal peptide removed." [PRO:CNA]
comment: Category=modification.
synonym: "ADAMTSL2/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003739 ! ADAMTS-like protein 2
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000037803
name: ADAMTS-like protein 2, signal peptide removed form (mouse)
def: "An ADAMTS-like protein 2, signal peptide removed form in mouse. UniProtKB:Q7TSK7, 30-957." [PMID:17509843, PRO:KRC]
comment: Category=organism-modification. Note: PMID:17509843 shows Edman degradation of the N-terminus of secreted mouse Adamtsl2 indicating that it begins with Ser30, corresponding to the predicted signal peptide cleavage between Ala29 and Ser30.
synonym: "PRO_0000249683" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "mADAMTSL2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q7TSK7, 30-957" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037802 ! ADAMTS-like protein 2, signal peptide removed form

[Term]
id: PR:Q7TSK7
name: ADAMTS-like protein 2 (mouse)
def: "An ADAMTS-like protein 2 that is encoded in the genome of mouse." [OMA:Q7TSK7, PMID:17509843, PRO:KRC, UniProtKB:Q7TSK7]
comment: Category=organism-gene.
synonym: "Tcp1" RELATED Gene-based [UniProtKB:Q7TSK7]
synonym: "Adamtsl2" RELATED Gene-based [UniProtKB:Q7TSK7]
synonym: "Kiaa0605" RELATED Gene-based [UniProtKB:Q7TSK7]
synonym: "mADAMTSL2" EXACT PRO-short-label [PRO:DNx]
synonym: "TCP-1 (mouse)" EXACT [UniProtKB:Q7TSK7]
synonym: "ADAMTSL-2 (mouse)" EXACT [UniProtKB:Q7TSK7]
synonym: "TSP1-repeat-containing protein 1 (mouse)" EXACT [UniProtKB:Q7TSK7]
xref: UniProtKB:Q7TSK7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003739 ! ADAMTS-like protein 2
relationship: has_gene_template MGI:1925044 ! Adamtsl2 (mouse)

[Term]
id: PR:000037804
name: ADAMTS-like protein 2, signal peptide removed N-glycosylasparagine form (mouse)
def: "An ADAMTS-like protein 2, signal peptide removed form (mouse) that includes at least one N-glycosylated asparagine residue. UniProtKB:Q7TSK7, 30-957, MOD:00160." [PMID:17509843, PRO:KRC]
comment: Category=organism-modification. Note: PMID:17509843 shows PMID:17509843 shows a major band of about 140 kDa isolated from transfected cells, but digestion with PNGaseF reduced its size to 110 kDa attributable to N-linked glycosylation. Treatment with heparitinase I+ III or chondroitinase ABC did not alter migration suggesting that there were no glycosaminoglycan chains attached.
synonym: "mADAMTSL2/SigPep-/NGlycoAsn+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q7TSK7, 30-957, MOD:00160" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:000037803 ! ADAMTS-like protein 2, signal peptide removed form (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000046265
name: ADAMTS-like protein 2, signal peptide removed form (human)
def: "An ADAMTS-like protein 2 (human) that has had the signal peptide removed. UniProtKB:Q86TH1, 23-951." [PRO:DNx, Reactome:R-HSA-5173091]
comment: Category=organism-modification.
synonym: "PRO_0000249682" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hADAMTSL2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q86TH1, 23-951" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5173091 "PR:000046265 located_in GO:0005788"
intersection_of: PR:Q86TH1 ! ADAMTS-like protein 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000003739
name: ADAMTS-like protein 2
def: "A protein that is a translation product of the human ADAMTSL2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Tcp1" RELATED Gene-based []
synonym: "TCP-1" EXACT []
synonym: "ADAMTSL2" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0605" RELATED Gene-based []
synonym: "ADAMTSL-2" EXACT []
synonym: "TSP1-repeats-containing protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000057552
name: ADAMTS-like protein 2 O-glycosylated 1 (human)
def: "An ADAMTS-like protein 2 (human) that has been O-glycosylated at the residue equivalent to Thr-909 of the amino acid sequence represented by UniProtKB:Q86TH1-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q86TH1-1, Thr-909, MOD:00005~GNO:G43417UB." [GlyGen:Q86TH1-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hADAMTSL2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q86TH1-1, Thr-909, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q86TH1 ! ADAMTS-like protein 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q86TH1
name: ADAMTS-like protein 2 (human)
def: "An ADAMTS-like protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q86TH1]
comment: Category=organism-gene.
synonym: "ADAMTSL2" RELATED Gene-based [UniProtKB:Q86TH1]
synonym: "KIAA0605" RELATED Gene-based [UniProtKB:Q86TH1]
synonym: "hADAMTSL2" EXACT PRO-short-label [PRO:DNx]
synonym: "ADAMTSL-2 (human)" EXACT [UniProtKB:Q86TH1]
xref: UniProtKB:Q86TH1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003739 ! ADAMTS-like protein 2
relationship: has_gene_template HGNC:14631 ! ADAMTSL2 (human)

[Term]
id: PR:000057551
name: ADAMTS-like protein 2 N-glycosylated 1 (human)
def: "An ADAMTS-like protein 2 (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:Q86TH1-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:Q86TH1-1, Asn-731, MOD:00160~GNO:G10486CT." [GlyGen:Q86TH1-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hADAMTSL2/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q86TH1-1, Asn-731, MOD:00160~GNO:G10486CT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q86TH1 ! ADAMTS-like protein 2 (human)
relationship: has_part GNO:G10486CT ! G10486CT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens