[Term]
id: PR:000003775
name: acireductone dioxygenase
def: "A protein that is a translation product of the human ADI1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ARD" EXACT []
synonym: "ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "ARD'" EXACT []
synonym: "SIPL" EXACT []
synonym: "Fe-ARD" EXACT []
synonym: "MTCBP1" RELATED Gene-based []
synonym: "Ni-ARD" EXACT []
synonym: "MTCBP-1" EXACT []
synonym: "HMFT1638" RELATED Gene-based []
synonym: "aci-reductone dioxygenase" EXACT []
synonym: "submergence-induced protein 2 homolog" EXACT []
synonym: "acireductone dioxygenase (Fe(2+)-requiring)" EXACT []
synonym: "acireductone dioxygenase (Ni(2+)-requiring)" EXACT []
synonym: "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase" EXACT []
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q562C9
name: acireductone dioxygenase (rat)
def: "An acireductone dioxygenase that is encoded in the genome of rat." [OMA:Q562C9, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Adi1" RELATED Gene-based [UniProtKB:Q562C9]
synonym: "Alp1" RELATED Gene-based [UniProtKB:Q562C9]
synonym: "rADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "Mtcbp1" RELATED Gene-based [UniProtKB:Q562C9]
synonym: "ARD (rat)" EXACT [UniProtKB:Q562C9]
synonym: "ARD' (rat)" EXACT [UniProtKB:Q562C9]
synonym: "Fe-ARD (rat)" EXACT [UniProtKB:Q562C9]
synonym: "Ni-ARD (rat)" EXACT [UniProtKB:Q562C9]
synonym: "MTCBP-1 (rat)" EXACT [UniProtKB:Q562C9]
synonym: "androgen-responsive ARD-like protein 1 (rat)" EXACT [UniProtKB:Q562C9]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (rat)" EXACT [UniProtKB:Q562C9]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (rat)" EXACT [UniProtKB:Q562C9]
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (rat)" EXACT [UniProtKB:Q562C9]
xref: UniProtKB:Q562C9
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template RGD:727828 ! Adi1 (rat)

[Term]
id: PR:Q6AWN0
name: acireductone dioxygenase (fruit fly)
def: "An acireductone dioxygenase that is encoded in the genome of fruit fly." [OMA:Q6AWN0, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Adi1" RELATED Gene-based [UniProtKB:Q6AWN0]
synonym: "CG32068" RELATED Gene-based [UniProtKB:Q6AWN0]
synonym: "fly-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "ARD (fruit fly)" EXACT [UniProtKB:Q6AWN0]
synonym: "ARD' (fruit fly)" EXACT [UniProtKB:Q6AWN0]
synonym: "Fe-ARD (fruit fly)" EXACT [UniProtKB:Q6AWN0]
synonym: "Ni-ARD (fruit fly)" EXACT [UniProtKB:Q6AWN0]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (fruit fly)" EXACT [UniProtKB:Q6AWN0]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (fruit fly)" EXACT [UniProtKB:Q6AWN0]
xref: UniProtKB:Q6AWN0
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template FlyBase:FBgn0052068 ! Adi1 (fruit fly)

[Term]
id: PR:Q54ER6
name: acireductone dioxygenase (Dictyostelium discoideum)
def: "An acireductone dioxygenase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54ER6, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "adi1" RELATED Gene-based [UniProtKB:Q54ER6]
synonym: "Dicty-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0291376" RELATED Gene-based [UniProtKB:Q54ER6]
synonym: "ARD (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
synonym: "ARD' (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
synonym: "Fe-ARD (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
synonym: "Ni-ARD (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (Dictyostelium discoideum)" EXACT [UniProtKB:Q54ER6]
xref: UniProtKB:Q54ER6
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template dictyBase:DDB_G0291376 ! adi1 (Dictyostelium discoideum)

[Term]
id: PR:Q9BV57-2
name: acireductone dioxygenase isoform h2 (human)
def: "An acireductone dioxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BV57-2." [PRO:DNx, UniProtKB:Q9BV57]
comment: Category=organism-sequence.
synonym: "hADI1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BV57-2
is_a: PR:Q9BV57 ! acireductone dioxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8W108-1
name: acireductone dioxygenase 3 isoform 1 (Arabidopsis thaliana)
def: "An acireductone dioxygenase 3 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8W108-1." [PRO:DNx, UniProtKB:Q8W108]
comment: Category=organism-sequence.
synonym: "At-ADI1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8W108-1
is_a: PR:Q8W108 ! acireductone dioxygenase 3 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:000042901
name: acireductone dioxygenase isoform 1
def: "An acireductone dioxygenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BV57-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "ADI1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003775 ! acireductone dioxygenase

[Term]
id: PR:Q20340
name: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (worm)
def: "An acireductone dioxygenase that is encoded in the genome of worm." [PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ADI1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (worm)" EXACT [UniProtKB:Q20340]
xref: UniProtKB:Q20340
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template WormBase:WBGene00009636 ! F42F12.4 (worm)

[Term]
id: PR:Q99JT9-1
name: acireductone dioxygenase isoform 1 (mouse)
def: "An acireductone dioxygenase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mADI1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99JT9-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042901 ! acireductone dioxygenase isoform 1

[Term]
id: PR:000026650
name: acireductone dioxygenase, initiator methionine removed form
def: "An acireductone dioxygenase that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "ADI1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003775 ! acireductone dioxygenase
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q99JT9
name: acireductone dioxygenase (mouse)
def: "An acireductone dioxygenase that is encoded in the genome of mouse." [OMA:Q99JT9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Adi1" RELATED Gene-based [UniProtKB:Q99JT9]
synonym: "mADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "Mtcbp1" RELATED Gene-based [UniProtKB:Q99JT9]
synonym: "ARD (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "ARD' (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "Fe-ARD (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "Ni-ARD (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "MTCBP-1 (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (mouse)" EXACT [UniProtKB:Q99JT9]
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (mouse)" EXACT [UniProtKB:Q99JT9]
xref: UniProtKB:Q99JT9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template MGI:2144929 ! Adi1 (mouse)

[Term]
id: PR:O94286
name: acireductone dioxygenase (Schizosaccharomyces pombe 972h-)
def: "An acireductone dioxygenase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "adi1" RELATED Gene-based [UniProtKB:O94286]
synonym: "SPBC887.01" RELATED Gene-based [UniProtKB:O94286]
synonym: "Spom972h-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "ARD (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
synonym: "ARD' (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
synonym: "Fe-ARD (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
synonym: "Ni-ARD (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94286]
xref: UniProtKB:O94286
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template PomBase:SPBC887.01 ! adi1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q5ZL43
name: acireductone dioxygenase (chicken)
def: "An acireductone dioxygenase that is encoded in the genome of chicken." [OMA:Q5ZL43, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ADI1" RELATED Gene-based [UniProtKB:Q5ZL43]
synonym: "MTCBP1" RELATED Gene-based [UniProtKB:Q5ZL43]
synonym: "chick-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_7o8" RELATED Gene-based [UniProtKB:Q5ZL43]
synonym: "ARD (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "ARD' (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "Fe-ARD (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "Ni-ARD (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "MTCBP-1 (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (chicken)" EXACT [UniProtKB:Q5ZL43]
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (chicken)" EXACT [UniProtKB:Q5ZL43]
xref: UniProtKB:Q5ZL43
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template NCBIGene:421918 ! ADI1 (chicken)

[Term]
id: PR:Q03677
name: acireductone dioxygenase (yeast)
def: "An acireductone dioxygenase that is encoded in the genome of yeast." [OMA:Q03677, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ADI1" RELATED Gene-based [UniProtKB:Q03677]
synonym: "yADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "YMR009W" RELATED Gene-based [UniProtKB:Q03677]
synonym: "YM8270.12" RELATED Gene-based [UniProtKB:Q03677]
synonym: "ARD (yeast)" EXACT [UniProtKB:Q03677]
synonym: "ARD' (yeast)" EXACT [UniProtKB:Q03677]
synonym: "Fe-ARD (yeast)" EXACT [UniProtKB:Q03677]
synonym: "Ni-ARD (yeast)" EXACT [UniProtKB:Q03677]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (yeast)" EXACT [UniProtKB:Q03677]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (yeast)" EXACT [UniProtKB:Q03677]
xref: UniProtKB:Q03677
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template SGD:S000004611 ! ADI1 (yeast)

[Term]
id: PR:Q9BV57
name: acireductone dioxygenase (human)
def: "An acireductone dioxygenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BV57]
comment: Category=organism-gene.
synonym: "ADI1" RELATED Gene-based [UniProtKB:Q9BV57]
synonym: "hADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "MTCBP1" RELATED Gene-based [UniProtKB:Q9BV57]
synonym: "HMFT1638" RELATED Gene-based [UniProtKB:Q9BV57]
synonym: "ARD (human)" EXACT [UniProtKB:Q9BV57]
synonym: "ARD' (human)" EXACT [UniProtKB:Q9BV57]
synonym: "Sip-L (human)" EXACT [UniProtKB:Q9BV57]
synonym: "Fe-ARD (human)" EXACT [UniProtKB:Q9BV57]
synonym: "Ni-ARD (human)" EXACT [UniProtKB:Q9BV57]
synonym: "MTCBP-1 (human)" EXACT [UniProtKB:Q9BV57]
synonym: "submergence-induced protein-like factor (human)" EXACT [UniProtKB:Q9BV57]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (human)" EXACT [UniProtKB:Q9BV57]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (human)" EXACT [UniProtKB:Q9BV57]
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (human)" EXACT [UniProtKB:Q9BV57]
xref: Reactome:R-HSA-1237109 "PR:Q9BV57 located_in GO:0005829"
xref: UniProtKB:Q9BV57
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template HGNC:30576 ! ADI1 (human)

[Term]
id: PR:Q6PBX5
name: acireductone dioxygenase (zebrafish)
def: "An acireductone dioxygenase that is encoded in the genome of zebrafish." [OMA:Q6PBX5, PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "adi1" RELATED Gene-based [UniProtKB:Q6PBX5]
synonym: "mtcbp1" RELATED Gene-based [UniProtKB:Q6PBX5]
synonym: "z-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:73201" RELATED Gene-based [UniProtKB:Q6PBX5]
synonym: "ARD (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "ARD' (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "Fe-ARD (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "Ni-ARD (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "MTCBP-1 (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) (zebrafish)" EXACT [UniProtKB:Q6PBX5]
synonym: "membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (zebrafish)" EXACT [UniProtKB:Q6PBX5]
xref: UniProtKB:Q6PBX5
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template ZFIN:ZDB-GENE-030131-2799 ! adi1 (zebrafish)

[Term]
id: PR:Q9BV57-1
name: acireductone dioxygenase isoform 1 (human)
def: "An acireductone dioxygenase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hADI1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BV57-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042901 ! acireductone dioxygenase isoform 1

[Term]
id: PR:Q8W108
name: acireductone dioxygenase 3 (Arabidopsis thaliana)
def: "An acireductone dioxygenase that is encoded in the genome of Arabidopsis thaliana." [PANTHER:PTHR23418:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ARD3" RELATED Gene-based [UniProtKB:Q8W108]
synonym: "At-ADI1" EXACT PRO-short-label [PRO:DNx]
synonym: "dl3395c" RELATED Gene-based [UniProtKB:Q8W108]
synonym: "At4g14710" RELATED Gene-based [UniProtKB:Q8W108]
synonym: "FCAALL.141" RELATED Gene-based [UniProtKB:Q8W108]
synonym: "ARD 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
synonym: "ARD' 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
synonym: "Fe-ARD 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
synonym: "Ni-ARD 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
synonym: "acireductone dioxygenase (Fe(2+)-requiring) 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
synonym: "acireductone dioxygenase (Ni(2+)-requiring) 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8W108]
xref: UniProtKB:Q8W108
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000003775 ! acireductone dioxygenase
relationship: has_gene_template Araport:AT4G14710 ! ARD3 (Arabidopsis thaliana)

[Term]
id: PR:Q562C9-1
name: acireductone dioxygenase isoform 1 (rat)
def: "An acireductone dioxygenase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rADI1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q562C9-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000042901 ! acireductone dioxygenase isoform 1