[Term]
id: PR:000004101
name: AP-2 complex subunit beta
def: "A protein that is a translation product of the human AP2B1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ADTB2" RELATED Gene-based []
synonym: "AP2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "AP105B" EXACT []
synonym: "CLAPB1" RELATED Gene-based []
synonym: "beta-adaptin" EXACT []
synonym: "beta-2-adaptin" EXACT []
synonym: "AP-2 complex subunit beta-1" EXACT []
synonym: "adaptor protein complex AP-2 subunit beta" EXACT []
synonym: "adapter-related protein complex 2 beta subunit" EXACT []
synonym: "adaptor-related protein complex 2 subunit beta" EXACT []
synonym: "clathrin assembly protein complex 2 beta large chain" EXACT []
synonym: "plasma membrane adaptor HA2/AP2 adaptin beta subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P63010-1
name: AP-2 complex subunit beta isoform 1 (human)
def: "An AP-2 complex subunit beta isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAP2B1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-416642 "PR:P63010-1 located_in GO:0030666"
xref: UniProtKB:P63010-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040061 ! AP-2 complex subunit beta isoform 1

[Term]
id: PR:P63010-2
name: AP-2 complex subunit beta isoform 2 (human)
def: "An AP-2 complex subunit beta isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAP2B1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63010-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040062 ! AP-2 complex subunit beta isoform 2

[Term]
id: PR:P63010-3
name: AP-2 complex subunit beta isoform h3 (human)
def: "An AP-2 complex subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63010-3." [PRO:DNx, UniProtKB:P63010]
comment: Category=organism-sequence.
synonym: "hAP2B1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "AP-2 complex subunit beta isoform Ap2beta-NY (human)" EXACT [UniProtKB:P63010]
xref: UniProtKB:P63010-3
is_a: PR:P63010 ! AP-2 complex subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63010
name: AP-2 complex subunit beta (human)
def: "An AP-2 complex subunit beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P63010]
comment: Category=organism-gene.
synonym: "ADTB2" RELATED Gene-based [UniProtKB:P63010]
synonym: "AP2B1" RELATED Gene-based [UniProtKB:P63010]
synonym: "CLAPB1" RELATED Gene-based [UniProtKB:P63010]
synonym: "hAP2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "AP105B (human)" EXACT [UniProtKB:P63010]
synonym: "beta-adaptin (human)" EXACT [UniProtKB:P63010]
synonym: "beta-2-adaptin (human)" EXACT [UniProtKB:P63010]
synonym: "adaptor protein complex AP-2 subunit beta (human)" EXACT [UniProtKB:P63010]
synonym: "adaptor-related protein complex 2 subunit beta (human)" EXACT [UniProtKB:P63010]
synonym: "clathrin assembly protein complex 2 beta large chain (human)" EXACT [UniProtKB:P63010]
synonym: "plasma membrane adaptor HA2/AP2 adaptin beta subunit (human)" EXACT [UniProtKB:P63010]
xref: Reactome:R-HSA-167690 "PR:P63010 located_in GO:0005886"
xref: Reactome:R-HSA-182166 "PR:P63010 located_in GO:0005829"
xref: Reactome:R-HSA-2130489 "PR:P63010 located_in GO:0030669"
xref: Reactome:R-HSA-6784827 "PR:P63010 located_in GO:0036020"
xref: UniProtKB:P63010
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004101 ! AP-2 complex subunit beta
relationship: has_gene_template HGNC:563 ! AP2B1 (human)

[Term]
id: PR:000045849
name: AP-2 complex subunit beta phosphorylated 1 (human)
def: "An AP-2 complex subunit beta (human) that has been phosphorylated on the residue at the position equivalent to Tyr-737 of the amino acid sequence represented by UniProtKB:P63010-1. Example: UniProtKB:P63010-1, Tyr-737, MOD:00048." [PMID:18938240, iPTMnet:P63010]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18938240). Status=unreviewed.
synonym: "hAP2B1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63010-1, Tyr-737, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P63010 ! AP-2 complex subunit beta (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens