[Term]
id: PR:000045918
name: serine/threonine-protein kinase ATR phosphorylated 1 (human)
def: "A serine/threonine-protein kinase ATR (human) that has been phosphorylated on the residue at the position equivalent to Thr-1989 of the amino acid sequence represented by UniProtKB:Q13535-1. Example: UniProtKB:Q13535-1, Thr-1989, MOD:00047." [PMID:21777809, iPTMnet:Q13535]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21777809). Status=unreviewed.
synonym: "hATR/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13535-1, Thr-1989, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13535 ! serine/threonine-protein kinase ATR (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000004499
name: serine/threonine-protein kinase ATR
def: "A protein that is a translation product of the human ATR gene, the yeast MEC1 gene, or 1:1 orthologs thereof." [PRO:DAN]
comment: Category=gene.
synonym: "ATR" EXACT PRO-short-label [PRO:DNx]
synonym: "FRP1" RELATED Gene-based []
synonym: "Kiaa4069" RELATED Gene-based []
synonym: "FRAP-related protein 1" EXACT []
synonym: "DNA-damage checkpoint kinase MEC1" EXACT []
synonym: "mitosis entry checkpoint protein 1" EXACT []
synonym: "ataxia telangiectasia and Rad3-related protein" EXACT []
xref: IUPHARobj:1935
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13535
name: serine/threonine-protein kinase ATR (human)
def: "A serine/threonine-protein kinase ATR that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13535]
comment: Category=organism-gene.
synonym: "ATR" RELATED Gene-based [UniProtKB:Q13535]
synonym: "FRP1" RELATED Gene-based [UniProtKB:Q13535]
synonym: "hATR" EXACT PRO-short-label [PRO:DNx]
synonym: "FRAP-related protein 1 (human)" EXACT [UniProtKB:Q13535]
synonym: "ataxia telangiectasia and Rad3-related protein (human)" EXACT [UniProtKB:Q13535]
xref: Reactome:R-HSA-912443 "PR:Q13535 located_in GO:0005654"
xref: DTO:03100034
xref: UniProtKB:Q13535
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004499 ! serine/threonine-protein kinase ATR
relationship: has_gene_template HGNC:882 ! ATR (human)

[Term]
id: PR:Q13535-2
name: serine/threonine-protein kinase ATR isoform h2 (human)
def: "A serine/threonine-protein kinase ATR (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13535-2." [PRO:DNx, UniProtKB:Q13535]
comment: Category=organism-sequence.
synonym: "hATR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13535-2
is_a: PR:Q13535 ! serine/threonine-protein kinase ATR (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13535-3
name: serine/threonine-protein kinase ATR isoform h3 (human)
def: "A serine/threonine-protein kinase ATR (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13535-3." [PRO:DNx, UniProtKB:Q13535]
comment: Category=organism-sequence.
synonym: "hATR/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13535-3
is_a: PR:Q13535 ! serine/threonine-protein kinase ATR (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13535-1
name: serine/threonine-protein kinase ATR isoform h1 (human)
def: "A serine/threonine-protein kinase ATR (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13535-1." [PRO:DNx, UniProtKB:Q13535]
comment: Category=organism-sequence.
synonym: "hATR/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13535-1
is_a: PR:Q13535 ! serine/threonine-protein kinase ATR (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens