[Term] id: PR:P56945-6 name: breast cancer anti-estrogen resistance protein 1 isoform h6 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-6." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-6 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046464 name: breast cancer anti-estrogen resistance protein 1 phosphorylated 2 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 165 and 664 of the amino acid sequence represented by UniProtKB:P56945. UniProtKB:P56945, Tyr-165/Tyr-664, MOD:00048." [PRO:DNx, Reactome:R-HSA-8848723] comment: Category=organism-modification. synonym: "hBCAR1/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P56945, Tyr-165/Tyr-664, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-8848723 "PR:000046464 located_in GO:0005829" is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046465 name: breast cancer anti-estrogen resistance protein 1 phosphorylated 3 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 234, 249, 267, 287, 306, 327, 362, 372, 387, 410, 664 and 666 of the amino acid sequence represented by UniProtKB:P56945. UniProtKB:P56945, Tyr-234/Tyr-249/Tyr-267/Tyr-287/Tyr-306/Tyr-327/Tyr-362/Tyr-372/Tyr-387/Tyr-410/Tyr-664/Tyr-666, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218739] comment: Category=organism-modification. synonym: "hBCAR1/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P56945, Tyr-234/Tyr-249/Tyr-267/Tyr-287/Tyr-306/Tyr-327/Tyr-362/Tyr-372/Tyr-387/Tyr-410/Tyr-664/Tyr-666, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5218739 "PR:000046465 located_in GO:0005829" is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945 name: breast cancer anti-estrogen resistance protein 1 (human) def: "A breast cancer anti-estrogen resistance protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-gene. synonym: "CAS" RELATED Gene-based [UniProtKB:P56945] synonym: "BCAR1" RELATED Gene-based [UniProtKB:P56945] synonym: "CASS1" RELATED Gene-based [UniProtKB:P56945] synonym: "CRKAS" RELATED Gene-based [UniProtKB:P56945] synonym: "hBCAR1" EXACT PRO-short-label [PRO:DNx] synonym: "p130cas (human)" EXACT [UniProtKB:P56945] synonym: "CRK-associated substrate (human)" EXACT [UniProtKB:P56945] synonym: "Cas scaffolding protein family member 1 (human)" EXACT [UniProtKB:P56945] xref: Reactome:R-HSA-201625 "PR:P56945 located_in GO:0005829" xref: UniProtKB:P56945 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000004676 ! breast cancer anti-estrogen resistance protein 1 relationship: has_gene_template HGNC:971 ! BCAR1 (human) [Term] id: PR:000046466 name: breast cancer anti-estrogen resistance protein 1 phosphotyrosine form (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P56945, MOD:00048." [PRO:DNx, Reactome:R-HSA-372645] comment: Category=organism-modification. synonym: "hBCAR1/PhosTyr+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P56945, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-372645 "PR:000046466 located_in GO:0005829" intersection_of: has_part MOD:00048 ! O4'-phospho-L-tyrosine intersection_of: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045842 name: breast cancer anti-estrogen resistance protein 1 phosphorylated 1 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-128 of the amino acid sequence represented by UniProtKB:P56945-1. Example: UniProtKB:P56945-1, Tyr-128, MOD:00048." [PMID:22710723, iPTMnet:P56945] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22710723). Status=unreviewed. synonym: "hBCAR1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P56945-1, Tyr-128, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-8 name: breast cancer anti-estrogen resistance protein 1 isoform h8 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-8." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-8 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-3 name: breast cancer anti-estrogen resistance protein 1 isoform h3 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-3." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-3 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-2 name: breast cancer anti-estrogen resistance protein 1 isoform h2 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-2." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-2 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-1 name: breast cancer anti-estrogen resistance protein 1 isoform h1 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-1." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-1 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-7 name: breast cancer anti-estrogen resistance protein 1 isoform h7 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-7." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h7" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-7 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000004676 name: breast cancer anti-estrogen resistance protein 1 def: "A protein that is a translation product of the human BCAR1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CAS" RELATED Gene-based [] synonym: "BCAR1" EXACT PRO-short-label [PRO:DNx] synonym: "CASS1" RELATED Gene-based [] synonym: "CRKAS" RELATED Gene-based [] synonym: "p130cas" EXACT [] synonym: "CRK-associated substrate" EXACT [] synonym: "cas scaffolding protein family member 1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P56945-5 name: breast cancer anti-estrogen resistance protein 1 isoform h5 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-5." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-5 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56945-4 name: breast cancer anti-estrogen resistance protein 1 isoform h4 (human) def: "A breast cancer anti-estrogen resistance protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56945-4." [PRO:DNx, UniProtKB:P56945] comment: Category=organism-sequence. synonym: "hBCAR1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56945-4 is_a: PR:P56945 ! breast cancer anti-estrogen resistance protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens