[Term] id: PR:000046474 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, transit peptide removed form (human) def: "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:O14874, 31-412." [PRO:DNx, Reactome:R-HSA-5693129] comment: Category=organism-modification. synonym: "PRO_0000023452" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hBCKDK/TransPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O14874, 31-412" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5693129 "PR:000046474 located_in GO:0005759" intersection_of: PR:O14874 ! [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) intersection_of: lacks_part SO:0000725 ! transit_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O14874 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) def: "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14874] comment: Category=organism-gene. synonym: "BCKDK" RELATED Gene-based [UniProtKB:O14874] synonym: "hBCKDK" EXACT PRO-short-label [PRO:DNx] synonym: "BCKDHKIN (human)" EXACT [UniProtKB:O14874] synonym: "BCKD-kinase (human)" EXACT [UniProtKB:O14874] synonym: "branched-chain alpha-ketoacid dehydrogenase kinase (human)" EXACT [UniProtKB:O14874] xref: DTO:03100040 xref: UniProtKB:O14874 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000004688 ! [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial relationship: has_gene_template HGNC:16902 ! BCKDK (human) [Term] id: PR:000004688 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial def: "A protein that is a translation product of the human BCKDK gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "BCKDK" EXACT PRO-short-label [PRO:DNx] synonym: "BCKDHKIN" EXACT [] synonym: "BCKD-kinase" EXACT [] synonym: "branched-chain alpha-ketoacid dehydrogenase kinase" EXACT [] xref: IUPHARobj:1939 is_a: PR:000000001 ! protein [Term] id: PR:O14874-1 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform 1 (human) def: "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hBCKDK/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O14874-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038012 ! [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform 1 [Term] id: PR:O14874-3 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform h3 (human) def: "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14874-3." [PRO:DNx, UniProtKB:O14874] comment: Category=organism-sequence. synonym: "hBCKDK/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O14874-3 is_a: PR:O14874 ! [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O14874-2 name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform h2 (human) def: "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14874-2." [PRO:DNx, UniProtKB:O14874] comment: Category=organism-sequence. synonym: "hBCKDK/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O14874-2 is_a: PR:O14874 ! [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens