[Term] id: PR:000035560 name: kinetochore scaffold 1 isoform 2 unphosphorylated form (human) def: "A kinetochore scaffold 1 isoform 2 unphosphorylated form in human." [PRO:KER] comment: Category=organism-modification. synonym: "hKNL1/iso:2/PhosRes-" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035559 ! kinetochore scaffold 1 isoform 2 unphosphorylated form [Term] id: PR:Q8NG31-2 name: kinetochore scaffold 1 isoform 2 (human) def: "A kinetochore scaffold 1 isoform 2 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hKNL1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8NG31-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035555 ! kinetochore scaffold 1 isoform 2 [Term] id: PR:Q8NG31-3 name: kinetochore scaffold 1 isoform h3 (human) def: "A kinetochore scaffold 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NG31-3." [PRO:DNx, UniProtKB:Q8NG31] comment: Category=organism-sequence. synonym: "hKNL1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8NG31-3 is_a: PR:Q8NG31 ! kinetochore scaffold 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000035558 name: kinetochore scaffold 1 isoform 2 phosphorylated 1 (human) def: "A kinetochore scaffold 1 isoform 2 phosphorylated 1 in human. UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046." [PMID:22660415, PRO:KER] comment: Category=organism-modification. Kinase=("MPS1"; PR:P33981). synonym: "hKNL1/iso:2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035557 ! kinetochore scaffold 1 isoform 2 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:Q8NG31-1 name: kinetochore scaffold 1 isoform 1 (human) def: "A kinetochore scaffold 1 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hKNL1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8NG31-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035553 ! kinetochore scaffold 1 isoform 1 [Term] id: PR:Q8NG31-4 name: kinetochore scaffold 1 isoform h4 (human) def: "A kinetochore scaffold 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NG31-4." [PRO:DNx, UniProtKB:Q8NG31] comment: Category=organism-sequence. synonym: "hKNL1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8NG31-4 is_a: PR:Q8NG31 ! kinetochore scaffold 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000005050 name: kinetochore scaffold 1 def: "A protein that is a translation product of the human KNL1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CT29" EXACT [] synonym: "KNL1" EXACT PRO-short-label [PRO:DNx] synonym: "CASC5" RELATED Gene-based [] synonym: "AF15q14" EXACT [] synonym: "blinkin" EXACT [] synonym: "KIAA1570" RELATED Gene-based [] synonym: "protein CASC5" EXACT [] synonym: "protein D40/AF15q14" EXACT [] synonym: "cancer/testis antigen 29" EXACT [] synonym: "kinetochore-null protein 1" EXACT [] synonym: "Bub-linking kinetochore protein" EXACT [] synonym: "ALL1-fused gene from chromosome 15q14" EXACT [] synonym: "cancer susceptibility candidate gene 5 protein" EXACT [] synonym: "cancer susceptibility candidate gene 5 protein homolog" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q8NG31 name: kinetochore scaffold 1 (human) def: "A kinetochore scaffold 1 that is encoded in the genome of human." [PMID:20624902, PRO:KER] comment: Category=organism-gene. synonym: "KNL1" RELATED Gene-based [UniProtKB:Q8NG31] synonym: "CASC5" RELATED Gene-based [UniProtKB:Q8NG31] synonym: "hKNL1" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1570" RELATED Gene-based [UniProtKB:Q8NG31] synonym: "CT29 (human)" EXACT [UniProtKB:Q8NG31] synonym: "AF15q14 (human)" EXACT [UniProtKB:Q8NG31] synonym: "blinkin (human)" EXACT [UniProtKB:Q8NG31] synonym: "protein CASC5 (human)" EXACT [UniProtKB:Q8NG31] synonym: "protein D40/AF15q14 (human)" EXACT [UniProtKB:Q8NG31] synonym: "cancer/testis antigen 29 (human)" EXACT [UniProtKB:Q8NG31] synonym: "kinetochore-null protein 1 (human)" EXACT [UniProtKB:Q8NG31] synonym: "Bub-linking kinetochore protein (human)" EXACT [UniProtKB:Q8NG31] synonym: "ALL1-fused gene from chromosome 15q14 protein (human)" EXACT [UniProtKB:Q8NG31] synonym: "cancer susceptibility candidate gene 5 protein (human)" EXACT [UniProtKB:Q8NG31] xref: Reactome:R-HSA-375322 "PR:Q8NG31 located_in GO:0005829" xref: Reactome:R-HSA-606296 "PR:Q8NG31 located_in GO:0005654" xref: UniProtKB:Q8NG31 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000005050 ! kinetochore scaffold 1 relationship: has_gene_template HGNC:24054 ! KNL1 (human)