[Term]
id: PR:000005058
name: extracellular calcium-sensing receptor
def: "A rhodopsin-like G-protein coupled receptor that is a translation product of the human CASR gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "CASR" EXACT PRO-short-label [PRO:DNx]
synonym: "CaSR" EXACT []
synonym: "PCAR1" RELATED Gene-based []
synonym: "PCaR1" EXACT []
synonym: "GPRC2A" RELATED Gene-based []
synonym: "parathyroid cell calcium-sensing receptor" EXACT []
xref: IUPHARobj:54
is_a: PR:000001094 ! rhodopsin-like G-protein coupled receptor

[Term]
id: PR:000046572
name: extracellular calcium-sensing receptor, signal peptide removed form (human)
def: "An extracellular calcium-sensing receptor (human) that has had the signal peptide removed. UniProtKB:P41180, 20-1078." [PRO:DNx, Reactome:R-HSA-420719]
comment: Category=organism-modification.
synonym: "hCASR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012946" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P41180, 20-1078" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-420719 "PR:000046572 located_in GO:0005886"
intersection_of: PR:P41180 ! extracellular calcium-sensing receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P41180
name: extracellular calcium-sensing receptor (human)
def: "An extracellular calcium-sensing receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P41180]
comment: Category=organism-gene.
synonym: "CASR" RELATED Gene-based [UniProtKB:P41180]
synonym: "PCAR1" RELATED Gene-based [UniProtKB:P41180]
synonym: "hCASR" EXACT PRO-short-label [PRO:DNx]
synonym: "hCasR" EXACT [UniProtKB:P41180]
synonym: "GPRC2A" RELATED Gene-based [UniProtKB:P41180]
synonym: "CaR (human)" EXACT [UniProtKB:P41180]
synonym: "CaSR (human)" EXACT [UniProtKB:P41180]
synonym: "parathyroid cell calcium-sensing receptor 1 (human)" EXACT [UniProtKB:P41180]
xref: DTO:02100050
xref: UniProtKB:P41180
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005058 ! extracellular calcium-sensing receptor
relationship: has_gene_template HGNC:1514 ! CASR (human)

[Term]
id: PR:P41180-2
name: extracellular calcium-sensing receptor isoform h2 (human)
def: "An extracellular calcium-sensing receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41180-2." [PRO:DNx, UniProtKB:P41180]
comment: Category=organism-sequence.
synonym: "hCASR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P41180-2
is_a: PR:P41180 ! extracellular calcium-sensing receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P41180-1
name: extracellular calcium-sensing receptor isoform h1 (human)
def: "An extracellular calcium-sensing receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41180-1." [PRO:DNx, UniProtKB:P41180]
comment: Category=organism-sequence.
synonym: "hCASR/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P41180-1
is_a: PR:P41180 ! extracellular calcium-sensing receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens