[Term]
id: PR:Q00535-1
name: cyclin-dependent kinase 5 isoform 1 (human)
def: "A cyclin-dependent kinase 5 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCDK5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q00535-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040211 ! cyclin-dependent kinase 5 isoform 1

[Term]
id: PR:P49615
name: cyclin-dependent kinase 5 (mouse)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of mouse." [OMA:P49615, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdk5" RELATED Gene-based [UniProtKB:P49615]
synonym: "Crk6" RELATED Gene-based [UniProtKB:P49615]
synonym: "Cdkn5" RELATED Gene-based [UniProtKB:P49615]
synonym: "mCDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "PSSALRE" RELATED Gene-based [UniProtKB:P49615]
synonym: "TPKII catalytic subunit (mouse)" EXACT [UniProtKB:P49615]
synonym: "cell division protein kinase 5 (mouse)" EXACT [UniProtKB:P49615]
synonym: "cyclin-dependent-like kinase 5 (mouse)" EXACT [UniProtKB:P49615]
synonym: "serine/threonine-protein kinase PSSALRE (mouse)" EXACT [UniProtKB:P49615]
synonym: "tau protein kinase II catalytic subunit (mouse)" EXACT [UniProtKB:P49615]
xref: UniProtKB:P49615
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template MGI:101765 ! Cdk5 (mouse)

[Term]
id: PR:G5ECH7
name: cyclin-dependent-like kinase 5 (worm)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of worm." [OMA:G5ECH7, PRO:DNx]
comment: Category=organism-gene.
synonym: "cdk-5" RELATED Gene-based [UniProtKB:G5ECH7]
synonym: "T27E9.3" RELATED Gene-based [UniProtKB:G5ECH7]
synonym: "CDK5 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division protein kinase 5 (worm)" EXACT [UniProtKB:G5ECH7]
xref: UniProtKB:G5ECH7
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template WormBase:WBGene00000407 ! cdk-5 (worm)

[Term]
id: PR:Q03114-1
name: cyclin-dependent kinase 5 isoform 1 (rat)
def: "A cyclin-dependent kinase 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rCDK5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03114-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040211 ! cyclin-dependent kinase 5 isoform 1

[Term]
id: PR:P17157
name: cyclin-dependent protein kinase PHO85 (yeast)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of yeast." [OMA:P17157, PRO:DNx]
comment: Category=organism-gene.
synonym: "SSG3" RELATED Gene-based [UniProtKB:P17157]
synonym: "PHO85" RELATED Gene-based [UniProtKB:P17157]
synonym: "yCDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "YPL031C" RELATED Gene-based [UniProtKB:P17157]
synonym: "P7102.18A" RELATED Gene-based [UniProtKB:P17157]
synonym: "negative regulator of the PHO system (yeast)" EXACT [UniProtKB:P17157]
synonym: "serine/threonine-protein kinase PHO85 (yeast)" EXACT [UniProtKB:P17157]
xref: UniProtKB:P17157
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template SGD:S000005952 ! PHO85 (yeast)

[Term]
id: PR:000005258
name: cyclin-dependent kinase 5
def: "A CDK2-related kinase that is a translation product of the human CDK5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "CRK6" EXACT []
synonym: "CDKN5" RELATED Gene-based []
synonym: "PSSALRE" RELATED Gene-based []
synonym: "TPKII catalytic subunit" EXACT []
synonym: "cell division protein kinase 5" EXACT []
synonym: "cyclin-dependent-like kinase 5" EXACT []
synonym: "serine/threonine-protein kinase PSSALRE" EXACT []
synonym: "tau protein kinase II catalytic subunit" EXACT []
xref: IUPHARobj:1977
is_a: PR:000003270 ! CDK2-related kinase

[Term]
id: PR:Q03114
name: cyclin-dependent kinase 5 (rat)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of rat." [OMA:Q03114, PANTHER:PTHR24056:SF110, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdk5" RELATED Gene-based [UniProtKB:Q03114]
synonym: "Cdkn5" RELATED Gene-based [UniProtKB:Q03114]
synonym: "rCDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "PSSALRE" RELATED Gene-based [UniProtKB:Q03114]
synonym: "TPKII catalytic subunit (rat)" EXACT [UniProtKB:Q03114]
synonym: "cell division protein kinase 5 (rat)" EXACT [UniProtKB:Q03114]
synonym: "cyclin-dependent-like kinase 5 (rat)" EXACT [UniProtKB:Q03114]
synonym: "serine/threonine-protein kinase PSSALRE (rat)" EXACT [UniProtKB:Q03114]
synonym: "tau protein kinase II catalytic subunit (rat)" EXACT [UniProtKB:Q03114]
xref: UniProtKB:Q03114
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template RGD:70514 ! Cdk5 (rat)

[Term]
id: PR:Q00535-2
name: cyclin-dependent kinase 5 isoform h2 (human)
def: "A cyclin-dependent kinase 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00535-2." [PRO:DNx, UniProtKB:Q00535]
comment: Category=organism-sequence.
synonym: "hCDK5/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase 5 isoform CDK5-SV (human)" EXACT [UniProtKB:Q00535]
xref: UniProtKB:Q00535-2
is_a: PR:Q00535 ! cyclin-dependent kinase 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q00535
name: cyclin-dependent kinase 5 (human)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "CDK5" RELATED Gene-based [UniProtKB:Q00535]
synonym: "CDKN5" RELATED Gene-based [UniProtKB:Q00535]
synonym: "hCDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "PSSALRE" RELATED Gene-based [UniProtKB:Q00535]
synonym: "TPKII catalytic subunit (human)" EXACT [UniProtKB:Q00535]
synonym: "cell division protein kinase 5 (human)" EXACT [PRO:DNx]
synonym: "cyclin-dependent-like kinase 5 (human)" EXACT [UniProtKB:Q00535]
synonym: "serine/threonine-protein kinase PSSALRE (human)" EXACT [UniProtKB:Q00535]
synonym: "tau protein kinase II catalytic subunit (human)" EXACT [UniProtKB:Q00535]
xref: Reactome:R-HSA-180064 "PR:Q00535 located_in GO:0005829"
xref: Reactome:R-HSA-8863586 "PR:Q00535 located_in GO:0005654"
xref: DTO:03100071
xref: UniProtKB:Q00535
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template HGNC:1774 ! CDK5 (human)

[Term]
id: PR:P25859
name: cyclin-dependent kinase B1-1 (Arabidopsis thaliana)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]
comment: Category=organism-gene.
synonym: "CDC2B" RELATED Gene-based [UniProtKB:P25859]
synonym: "At-CDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "CDKB1-1" RELATED Gene-based [UniProtKB:P25859]
synonym: "At3g54180" RELATED Gene-based [UniProtKB:P25859]
synonym: "F24B22.140" RELATED Gene-based [UniProtKB:P25859]
synonym: "CDKB1;1 (Arabidopsis thaliana)" EXACT [UniProtKB:P25859]
synonym: "cell division control protein 2 homolog B (Arabidopsis thaliana)" EXACT [UniProtKB:P25859]
xref: UniProtKB:P25859
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template Araport:AT3G54180 ! CDKB1-1 (Arabidopsis thaliana)

[Term]
id: PR:P48609
name: cyclin-dependent kinase 5 homolog (fruit fly)
def: "A cyclin-dependent kinase 5 that is encoded in the genome of fruit fly." [OMA:P48609, PANTHER:PTHR24056:SF110, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdk5" RELATED Gene-based [UniProtKB:P48609]
synonym: "CG8203" RELATED Gene-based [UniProtKB:P48609]
synonym: "fly-CDK5" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division protein kinase 5 (fruit fly)" EXACT [UniProtKB:P48609]
xref: UniProtKB:P48609
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000005258 ! cyclin-dependent kinase 5
relationship: has_gene_template FlyBase:FBgn0013762 ! Cdk5 (fruit fly)

[Term]
id: PR:000040211
name: cyclin-dependent kinase 5 isoform 1
def: "A cyclin-dependent kinase 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00535-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CDK5/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005258 ! cyclin-dependent kinase 5

[Term]
id: PR:000046677
name: cyclin-dependent kinase 5 phosphorylated 2 (human)
def: "A cyclin-dependent kinase 5 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-15 and phosphoserine at position 159 of the amino acid sequence represented by UniProtKB:Q00535-1. Example: UniProtKB:Q00535-1, Tyr-15, MOD:00048|Ser-159, MOD:00046." [PRO:DNx, Reactome:R-HSA-6805249]
comment: Category=organism-modification.
synonym: "hCDK5/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q00535-1, Tyr-15, MOD:00048|Ser-159, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6805249 "PR:000046677 located_in GO:0005654"
is_a: PR:Q00535 ! cyclin-dependent kinase 5 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046676
name: cyclin-dependent kinase 5 phosphorylated 1 (human)
def: "A cyclin-dependent kinase 5 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-15 of the amino acid sequence represented by UniProtKB:Q00535. UniProtKB:Q00535, Tyr-15, MOD:00048." [PRO:DNx, Reactome:R-HSA-399809]
comment: Category=organism-modification.
synonym: "hCDK5/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q00535, Tyr-15, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-399809 "PR:000046676 located_in GO:0005829"
is_a: PR:Q00535 ! cyclin-dependent kinase 5 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49615-1
name: cyclin-dependent kinase 5 isoform 1 (mouse)
def: "A cyclin-dependent kinase 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCDK5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49615-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040211 ! cyclin-dependent kinase 5 isoform 1