[Term] id: PR:A8TX70 name: collagen alpha-5(VI) chain (human) def: "A collagen alpha-5(VI) chain that is encoded in the genome of human." [PRO:DNx, UniProtKB:A8TX70] comment: Category=organism-gene. synonym: "VWA4" RELATED Gene-based [UniProtKB:A8TX70] synonym: "COL6A5" RELATED Gene-based [UniProtKB:A8TX70] synonym: "COL29A1" RELATED Gene-based [UniProtKB:A8TX70] synonym: "hCOL6A5" EXACT PRO-short-label [PRO:DNx] synonym: "collagen alpha-1(XXIX) chain (human)" EXACT [UniProtKB:A8TX70] synonym: "von Willebrand factor A domain-containing protein 4 (human)" EXACT [UniProtKB:A8TX70] xref: UniProtKB:A8TX70 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000005712 ! collagen alpha-5(VI) chain relationship: has_gene_template HGNC:26674 ! COL6A5 (human) [Term] id: PR:000046978 name: collagen alpha-5(VI) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:A8TX70, 19-2615, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-2023504, Reactome:R-HSA-2127508] comment: Category=organism-modification. synonym: "hCOL6A5/SigPep-/5hL4hP+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_5000294475, MOD:00037|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023504 "PR:000046978 located_in GO:0005788" xref: Reactome:R-HSA-2127508 "PR:000046978 located_in GO:0005576" intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046976 name: collagen alpha-5(VI) chain, signal peptide removed 5-hydroxy-lysine form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine. UniProtKB:A8TX70, 19-2615, MOD:00037." [PRO:DNx, Reactome:R-HSA-2023506, Reactome:R-HSA-2127503] comment: Category=organism-modification. synonym: "hCOL6A5/SigPep-/5HyLys+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_5000294475, MOD:00037" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023506 "PR:000046976 located_in GO:0005788" xref: Reactome:R-HSA-2127503 "PR:000046976 located_in GO:0005576" intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046977 name: collagen alpha-5(VI) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:A8TX70, 19-2615, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2023495, Reactome:R-HSA-2127520] comment: Category=organism-modification. synonym: "hCOL6A5/SigPep-/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_5000294475, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023495 "PR:000046977 located_in GO:0005788" xref: Reactome:R-HSA-2127520 "PR:000046977 located_in GO:0005576" intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046974 name: collagen alpha-5(VI) chain, signal peptide removed 3-hydroxy-proline and 4-hydroxy-proline form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed and that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:A8TX70, 19-2615, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2023498, Reactome:R-HSA-2127518] comment: Category=organism-modification. synonym: "hCOL6A5/SigPep-/3hP4hP+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_5000294475, MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023498 "PR:000046974 located_in GO:0005788" xref: Reactome:R-HSA-2127518 "PR:000046974 located_in GO:0005576" intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046975 name: collagen alpha-5(VI) chain, signal peptide removed 4-hydroxy-proline form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed and that includes at least one 4-hydroxy-proline. UniProtKB:A8TX70, 19-2615, MOD:00039." [PRO:DNx, Reactome:R-HSA-2023499, Reactome:R-HSA-2127499] comment: Category=organism-modification. synonym: "hCOL6A5/SigPep-/4HyPro+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_5000294475, MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023499 "PR:000046975 located_in GO:0005788" xref: Reactome:R-HSA-2127499 "PR:000046975 located_in GO:0005576" intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046973 name: collagen alpha-5(VI) chain, signal peptide removed form (human) def: "A collagen alpha-5(VI) chain (human) that has had the signal peptide removed. UniProtKB:A8TX70, 19-2615." [PRO:DNx, Reactome:R-HSA-2023510, Reactome:R-HSA-2127532] comment: Category=organism-modification. synonym: "PRO_5000294475" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hCOL6A5/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:A8TX70, 19-2615" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2023510 "PR:000046973 located_in GO:0005788" xref: Reactome:R-HSA-2127532 "PR:000046973 located_in GO:0005576" intersection_of: PR:A8TX70 ! collagen alpha-5(VI) chain (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000005712 name: collagen alpha-5(VI) chain def: "A protein that is a translation product of the human COL6A5 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "VWA4" RELATED Gene-based [] synonym: "COL6A5" EXACT PRO-short-label [PRO:DNx] synonym: "COL29A1" RELATED Gene-based [] synonym: "collagen alpha-1(XXIX) chain" EXACT [] synonym: "von Willebrand factor A domain-containing protein 4" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:A8TX70-2 name: collagen alpha-5(VI) chain isoform h2 (human) def: "A collagen alpha-5(VI) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A8TX70-2." [PRO:DNx, UniProtKB:A8TX70] comment: Category=organism-sequence. synonym: "hCOL6A5/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A8TX70-2 is_a: PR:A8TX70 ! collagen alpha-5(VI) chain (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:A8TX70-1 name: collagen alpha-5(VI) chain isoform h1 (human) def: "A collagen alpha-5(VI) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A8TX70-1." [PRO:DNx, UniProtKB:A8TX70] comment: Category=organism-sequence. synonym: "hCOL6A5/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A8TX70-1 is_a: PR:A8TX70 ! collagen alpha-5(VI) chain (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens