[Term]
id: PR:000005731
name: catechol O-methyltransferase
def: "A protein that is a translation product of the human COMT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COMT" EXACT PRO-short-label [PRO:DNx]
synonym: "Comt1" RELATED Gene-based []
xref: IUPHARobj:2472
is_a: PR:000000001 ! protein

[Term]
id: PR:P21964-1
name: catechol O-methyltransferase isoform Membrane-bound (human)
def: "A catechol O-methyltransferase isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOMT/iso:Membrane-bound" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform MB-COMT (human)" EXACT [UniProtKB:P21964]
xref: UniProtKB:P21964-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025997 ! catechol O-methyltransferase isoform 1

[Term]
id: PR:P21964-2
name: catechol O-methyltransferase isoform Soluble (human)
def: "A catechol O-methyltransferase isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOMT/iso:Soluble" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform S-COMT (human)" EXACT [UniProtKB:P21964]
xref: UniProtKB:P21964-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025999 ! catechol O-methyltransferase isoform 2

[Term]
id: PR:P21964
name: catechol O-methyltransferase (human)
def: "A catechol O-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P21964]
comment: Category=organism-gene.
synonym: "COMT" RELATED Gene-based [UniProtKB:P21964]
synonym: "hCOMT" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-175974 "PR:P21964 located_in GO:0005829"
xref: Reactome:R-HSA-379386 "PR:P21964 located_in GO:0005886"
xref: UniProtKB:P21964
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template HGNC:2228 ! COMT (human)