[Term]
id: PR:000006036
name: Src substrate cortactin
def: "A protein that is a translation product of the human CTTN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CTTN" EXACT PRO-short-label [PRO:DNx]
synonym: "EMS1" RELATED Gene-based []
synonym: "amplaxin" EXACT []
synonym: "oncogene EMS1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q14247
name: Src substrate cortactin (human)
def: "A Src substrate cortactin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14247]
comment: Category=organism-gene.
synonym: "CTTN" RELATED Gene-based [UniProtKB:Q14247]
synonym: "EMS1" RELATED Gene-based [UniProtKB:Q14247]
synonym: "hCTTN" EXACT PRO-short-label [PRO:DNx]
synonym: "amplaxin (human)" EXACT [UniProtKB:Q14247]
synonym: "oncogene EMS1 (human)" EXACT [UniProtKB:Q14247]
xref: Reactome:R-HSA-201894 "PR:Q14247 located_in GO:0005829"
xref: UniProtKB:Q14247
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006036 ! Src substrate cortactin
relationship: has_gene_template HGNC:3338 ! CTTN (human)

[Term]
id: PR:Q14247-3
name: Src substrate cortactin isoform h3 (human)
def: "A Src substrate cortactin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14247-3." [PRO:DNx, UniProtKB:Q14247]
comment: Category=organism-sequence.
synonym: "hCTTN/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14247-3
is_a: PR:Q14247 ! Src substrate cortactin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14247-2
name: Src substrate cortactin isoform h2 (human)
def: "A Src substrate cortactin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14247-2." [PRO:DNx, UniProtKB:Q14247]
comment: Category=organism-sequence.
synonym: "hCTTN/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14247-2
is_a: PR:Q14247 ! Src substrate cortactin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14247-1
name: Src substrate cortactin isoform h1 (human)
def: "A Src substrate cortactin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14247-1." [PRO:DNx, UniProtKB:Q14247]
comment: Category=organism-sequence.
synonym: "hCTTN/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14247-1
is_a: PR:Q14247 ! Src substrate cortactin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047100
name: Src substrate cortactin phosphorylated 2 (human)
def: "A Src substrate cortactin (human) that has been phosphorylated on the residue at the position equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:Q14247. UniProtKB:Q14247, Ser-113, MOD:00046." [PRO:DNx, Reactome:R-HSA-442842]
comment: Category=organism-modification.
synonym: "hCTTN/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q14247, Ser-113, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-442842 "PR:000047100 located_in GO:0005829"
is_a: PR:Q14247 ! Src substrate cortactin (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045925
name: Src substrate cortactin phosphorylated 1 (human)
def: "A Src substrate cortactin (human) that has been phosphorylated on the residue at the position equivalent to Ser-298 of the amino acid sequence represented by UniProtKB:Q14247-1. Example: UniProtKB:Q14247-1, Ser-298, MOD:00046." [PMID:20363754, iPTMnet:Q14247]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20363754). Status=unreviewed.
synonym: "hCTTN/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q14247-1, Ser-298, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q14247 ! Src substrate cortactin (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens