[Term]
id: PR:000041058
name: type I iodothyronine deiodinase isoform 1
def: "A type I iodothyronine deiodinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61153-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DIO1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006480 ! type I iodothyronine deiodinase

[Term]
id: PR:P49895-5
name: type I iodothyronine deiodinase isoform h5 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-5." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform e (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-5
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q61153
name: type I iodothyronine deiodinase (mouse)
def: "A type I iodothyronine deiodinase that is encoded in the genome of mouse." [OMA:Q61153, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio1" RELATED Gene-based [UniProtKB:Q61153]
synonym: "Itdi1" RELATED Gene-based [UniProtKB:Q61153]
synonym: "Txdi1" RELATED Gene-based [UniProtKB:Q61153]
synonym: "mDIO1" EXACT PRO-short-label [PRO:DNx]
synonym: "5DI (mouse)" EXACT [UniProtKB:Q61153]
synonym: "DIOI (mouse)" EXACT [UniProtKB:Q61153]
synonym: "type 1 DI (mouse)" EXACT [UniProtKB:Q61153]
synonym: "type-I 5'-deiodinase (mouse)" EXACT [UniProtKB:Q61153]
xref: UniProtKB:Q61153
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006480 ! type I iodothyronine deiodinase
relationship: has_gene_template MGI:94896 ! Dio1 (mouse)

[Term]
id: PR:P24389
name: type I iodothyronine deiodinase (rat)
def: "A type I iodothyronine deiodinase that is encoded in the genome of rat." [OMA:P24389, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio1" RELATED Gene-based [UniProtKB:P24389]
synonym: "Itdi1" RELATED Gene-based [UniProtKB:P24389]
synonym: "Txdi1" RELATED Gene-based [UniProtKB:P24389]
synonym: "rDIO1" EXACT PRO-short-label [PRO:DNx]
synonym: "5DI (rat)" EXACT [UniProtKB:P24389]
synonym: "DIOI (rat)" EXACT [UniProtKB:P24389]
synonym: "type 1 DI (rat)" EXACT [UniProtKB:P24389]
synonym: "type-I 5'-deiodinase (rat)" EXACT [UniProtKB:P24389]
xref: UniProtKB:P24389
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006480 ! type I iodothyronine deiodinase
relationship: has_gene_template RGD:2504 ! Dio1 (rat)

[Term]
id: PR:P49895-8
name: type I iodothyronine deiodinase isoform h8 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-8." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h8" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform m (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-8
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O42411
name: type I iodothyronine deiodinase (chicken)
def: "A type I iodothyronine deiodinase that is encoded in the genome of chicken." [OMA:O42411, PRO:DNx]
comment: Category=organism-gene.
synonym: "DIO1" RELATED Gene-based [UniProtKB:O42411]
synonym: "chick-DIO1" EXACT PRO-short-label [PRO:DNx]
synonym: "5DI (chicken)" EXACT [UniProtKB:O42411]
synonym: "DIOI (chicken)" EXACT [UniProtKB:O42411]
synonym: "type 1 DI (chicken)" EXACT [UniProtKB:O42411]
synonym: "type-I 5'-deiodinase (chicken)" EXACT [UniProtKB:O42411]
xref: UniProtKB:O42411
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000006480 ! type I iodothyronine deiodinase
relationship: has_gene_template CGNC:8160 ! DIO1 (chicken)

[Term]
id: PR:P49895-4
name: type I iodothyronine deiodinase isoform h4 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-4." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform d (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-4
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895-7
name: type I iodothyronine deiodinase isoform h7 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-7." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform l (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-7
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895-6
name: type I iodothyronine deiodinase isoform h6 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-6." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform k (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-6
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895
name: type I iodothyronine deiodinase (human)
def: "A type I iodothyronine deiodinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-gene.
synonym: "DIO1" RELATED Gene-based [UniProtKB:P49895]
synonym: "ITDI1" RELATED Gene-based [UniProtKB:P49895]
synonym: "TXDI1" RELATED Gene-based [UniProtKB:P49895]
synonym: "hDIO1" EXACT PRO-short-label [PRO:DNx]
synonym: "5DI (human)" EXACT [UniProtKB:P49895]
synonym: "DIOI (human)" EXACT [UniProtKB:P49895]
synonym: "type 1 DI (human)" EXACT [UniProtKB:P49895]
synonym: "type-I 5'-deiodinase (human)" EXACT [UniProtKB:P49895]
xref: Reactome:R-HSA-2980823 "PR:P49895 located_in GO:0005886"
xref: UniProtKB:P49895
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006480 ! type I iodothyronine deiodinase
relationship: has_gene_template HGNC:2883 ! DIO1 (human)

[Term]
id: PR:Q61153-1
name: type I iodothyronine deiodinase isoform 1 (mouse)
def: "A type I iodothyronine deiodinase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDIO1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q61153-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000041058 ! type I iodothyronine deiodinase isoform 1

[Term]
id: PR:P49895-3
name: type I iodothyronine deiodinase isoform h3 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-3." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform c/f (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-3
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895-2
name: type I iodothyronine deiodinase isoform h2 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-2." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform b (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-2
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895-1
name: type I iodothyronine deiodinase isoform h1 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-1." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform a (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-1
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49895-9
name: type I iodothyronine deiodinase isoform h9 (human)
def: "A type I iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49895-9." [PRO:DNx, UniProtKB:P49895]
comment: Category=organism-sequence.
synonym: "hDIO1/iso:h9" EXACT PRO-short-label [PRO:DNx]
synonym: "type I iodothyronine deiodinase isoform s (human)" EXACT [UniProtKB:P49895]
xref: UniProtKB:P49895-9
is_a: PR:P49895 ! type I iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P24389-1
name: type I iodothyronine deiodinase isoform 1 (rat)
def: "A type I iodothyronine deiodinase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDIO1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24389-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000041058 ! type I iodothyronine deiodinase isoform 1

[Term]
id: PR:000006480
name: type I iodothyronine deiodinase
def: "A protein that is a translation product of the human DIO1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "5DI" EXACT []
synonym: "DIO1" EXACT PRO-short-label [PRO:DNx]
synonym: "DIOI" EXACT []
synonym: "ITDI1" RELATED Gene-based []
synonym: "TXDI1" RELATED Gene-based []
synonym: "type 1 DI" EXACT []
synonym: "type-I 5'-deiodinase" EXACT []
xref: IUPHARobj:2481
is_a: PR:000000001 ! protein