[Term]
id: PR:000006962
name: translation initiation factor eIF-2B subunit alpha
def: "A protein that is a translation product of the human EIF2B1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "EIF2BA" RELATED Gene-based []
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q14232
name: translation initiation factor eIF-2B subunit alpha (human)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14232]
comment: Category=organism-gene.
synonym: "EIF2B1" RELATED Gene-based [UniProtKB:Q14232]
synonym: "EIF2BA" RELATED Gene-based [UniProtKB:Q14232]
synonym: "hEIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (human)" EXACT [UniProtKB:Q14232]
xref: Reactome:R-HSA-72517 "PR:Q14232 located_in GO:0005829"
xref: UniProtKB:Q14232
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template HGNC:3257 ! EIF2B1 (human)

[Term]
id: PR:Q99LC8
name: translation initiation factor eIF-2B subunit alpha (mouse)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of mouse." [OMA:Q99LC8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif2b1" RELATED Gene-based [UniProtKB:Q99LC8]
synonym: "mEIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (mouse)" EXACT [UniProtKB:Q99LC8]
xref: UniProtKB:Q99LC8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template MGI:2384802 ! Eif2b1 (mouse)

[Term]
id: PR:000040518
name: translation initiation factor eIF-2B subunit alpha isoform 1
def: "A translation initiation factor eIF-2B subunit alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14232-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "EIF2B1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006962 ! translation initiation factor eIF-2B subunit alpha

[Term]
id: PR:Q9USP0
name: translation initiation factor eIF-2B subunit alpha (Schizosaccharomyces pombe 972h-)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9USP0, PANTHER:PTHR10233:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "tif221" RELATED Gene-based [UniProtKB:Q9USP0]
synonym: "SPCC11E10.07c" RELATED Gene-based [UniProtKB:Q9USP0]
synonym: "Spom972h-EIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9USP0]
xref: UniProtKB:Q9USP0
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template PomBase:SPCC11E10.07c ! tif221 (Schizosaccharomyces pombe)

[Term]
id: PR:P14741
name: translation initiation factor eIF-2B subunit alpha (yeast)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of yeast." [OMA:P14741, PANTHER:PTHR10233:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "AAS2" RELATED Gene-based [UniProtKB:P14741]
synonym: "GCN3" RELATED Gene-based [UniProtKB:P14741]
synonym: "TIF221" RELATED Gene-based [UniProtKB:P14741]
synonym: "YKR026C" RELATED Gene-based [UniProtKB:P14741]
synonym: "yEIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "GCD complex subunit GCN3 (yeast)" EXACT [UniProtKB:P14741]
synonym: "translational activator GCN3 (yeast)" EXACT [UniProtKB:P14741]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (yeast)" EXACT [UniProtKB:P14741]
synonym: "guanine nucleotide exchange factor subunit GCN3 (yeast)" EXACT [UniProtKB:P14741]
xref: UniProtKB:P14741
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template SGD:S000001734 ! GCN3 (yeast)

[Term]
id: PR:Q14232-2
name: translation initiation factor eIF-2B subunit alpha isoform h2 (human)
def: "A translation initiation factor eIF-2B subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14232-2." [PRO:DNx, UniProtKB:Q14232]
comment: Category=organism-sequence.
synonym: "hEIF2B1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14232-2
is_a: PR:Q14232 ! translation initiation factor eIF-2B subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14232-1
name: translation initiation factor eIF-2B subunit alpha isoform 1 (human)
def: "A translation initiation factor eIF-2B subunit alpha isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hEIF2B1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14232-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040518 ! translation initiation factor eIF-2B subunit alpha isoform 1

[Term]
id: PR:Q64270
name: translation initiation factor eIF-2B subunit alpha (rat)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of rat." [OMA:Q64270, PANTHER:PTHR10233:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif2b1" RELATED Gene-based [UniProtKB:Q64270]
synonym: "Eif2ba" RELATED Gene-based [UniProtKB:Q64270]
synonym: "rEIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (rat)" EXACT [UniProtKB:Q64270]
xref: UniProtKB:Q64270
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template RGD:620819 ! Eif2b1 (rat)

[Term]
id: PR:P34604
name: probable translation initiation factor eIF-2B subunit alpha (worm)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of worm." [OMA:P34604, PANTHER:PTHR10233:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "ZK1098.4" RELATED Gene-based [UniProtKB:P34604]
synonym: "EIF2B1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (worm)" EXACT [UniProtKB:P34604]
xref: UniProtKB:P34604
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template WormBase:WBGene00014221 ! ZK1098.4 (worm)

[Term]
id: PR:Q99LC8-1
name: translation initiation factor eIF-2B subunit alpha isoform 1 (mouse)
def: "A translation initiation factor eIF-2B subunit alpha isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mEIF2B1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99LC8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040518 ! translation initiation factor eIF-2B subunit alpha isoform 1

[Term]
id: PR:Q64270-1
name: translation initiation factor eIF-2B subunit alpha isoform 1 (rat)
def: "A translation initiation factor eIF-2B subunit alpha isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rEIF2B1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64270-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040518 ! translation initiation factor eIF-2B subunit alpha isoform 1

[Term]
id: PR:Q54I81
name: translation initiation factor eIF-2B subunit alpha (Dictyostelium discoideum)
def: "A translation initiation factor eIF-2B subunit alpha that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54I81, PANTHER:PTHR10233:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "eif2b1" RELATED Gene-based [UniProtKB:Q54I81]
synonym: "DDB_G0288961" RELATED Gene-based [UniProtKB:Q54I81]
synonym: "Dicty-EIF2B1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit alpha (Dictyostelium discoideum)" EXACT [UniProtKB:Q54I81]
xref: UniProtKB:Q54I81
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000006962 ! translation initiation factor eIF-2B subunit alpha
relationship: has_gene_template dictyBase:DDB_G0288961 ! eif2b1 (Dictyostelium discoideum)