[Term]
id: PR:000025754
name: fumarate hydratase, mitochondrial isoform 1
def: "A fumarate hydratase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97807-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "FH/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007511 ! fumarate hydratase, mitochondrial

[Term]
id: PR:000025757
name: fumarate hydratase, mitochondrial isoform 2
def: "A fumarate hydratase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97807-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "FH/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007511 ! fumarate hydratase, mitochondrial

[Term]
id: PR:Q7SX99-2
name: fumarate hydratase, mitochondrial isoform Cytoplasmic (zebrafish)
def: "A fumarate hydratase, mitochondrial (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7SX99-2." [PRO:DNx, UniProtKB:Q7SX99]
comment: Category=organism-sequence.
synonym: "z-FH/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7SX99-2
is_a: PR:Q7SX99 ! fumarate hydratase, mitochondrial (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:Q7SX99-1
name: fumarate hydratase, mitochondrial isoform Mitochondrial (zebrafish)
def: "A fumarate hydratase, mitochondrial (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7SX99-1." [PRO:DNx, UniProtKB:Q7SX99]
comment: Category=organism-sequence.
synonym: "z-FH/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7SX99-1
is_a: PR:Q7SX99 ! fumarate hydratase, mitochondrial (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:P07954-2
name: fumarate hydratase, mitochondrial isoform 2 (human)
def: "A fumarate hydratase, mitochondrial isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hFH/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarate hydratase isoform cytoplasmic (human)" BROAD [PRO:DNx]
xref: UniProtKB:P07954-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025757 ! fumarate hydratase, mitochondrial isoform 2

[Term]
id: PR:P07954-1
name: fumarate hydratase, mitochondrial isoform 1 (human)
def: "A fumarate hydratase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hFH/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarate hydratase isoform mitochondrial (human)" BROAD [PRO:DNx]
xref: UniProtKB:P07954-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025754 ! fumarate hydratase, mitochondrial isoform 1

[Term]
id: PR:P07954
name: fumarate hydratase, mitochondrial (human)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07954]
comment: Category=organism-gene.
synonym: "FH" RELATED Gene-based [UniProtKB:P07954]
synonym: "hFH" EXACT PRO-short-label [PRO:DNx]
synonym: "HsFH" EXACT [UniProtKB:P07954]
synonym: "fumarase (human)" EXACT [UniProtKB:P07954]
xref: UniProtKB:P07954
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template HGNC:3700 ! FH (human)

[Term]
id: PR:000007511
name: fumarate hydratase, mitochondrial
def: "A protein that is a translation product of the human FH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FH" EXACT PRO-short-label [PRO:DNx]
synonym: "Fh1" RELATED Gene-based []
synonym: "EF-3" EXACT []
synonym: "fumarase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:P97807-2
name: fumarate hydratase, mitochondrial isoform 2 (mouse)
def: "A fumarate hydratase, mitochondrial isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mFH/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarate hydratase isoform cytoplasmic (mouse)" BROAD [PRO:DNx]
xref: UniProtKB:P97807-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025757 ! fumarate hydratase, mitochondrial isoform 2

[Term]
id: PR:P97807-1
name: fumarate hydratase, mitochondrial isoform 1 (mouse)
def: "A fumarate hydratase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mFH/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarate hydratase isoform mitochondrial (mouse)" BROAD [PRO:DNx]
xref: UniProtKB:P97807-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025754 ! fumarate hydratase, mitochondrial isoform 1

[Term]
id: PR:Q54VA2-1
name: fumarate hydratase, mitochondrial isoform Mitochondrial (Dictyostelium discoideum)
def: "A fumarate hydratase, mitochondrial (Dictyostelium discoideum) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q54VA2-1." [PRO:DNx, UniProtKB:Q54VA2]
comment: Category=organism-sequence.
synonym: "Dicty-FH/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54VA2-1
is_a: PR:Q54VA2 ! fumarate hydratase, mitochondrial (Dictyostelium discoideum)
relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum

[Term]
id: PR:Q54VA2-2
name: fumarate hydratase, mitochondrial isoform Cytoplasmic (Dictyostelium discoideum)
def: "A fumarate hydratase, mitochondrial (Dictyostelium discoideum) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q54VA2-2." [PRO:DNx, UniProtKB:Q54VA2]
comment: Category=organism-sequence.
synonym: "Dicty-FH/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54VA2-2
is_a: PR:Q54VA2 ! fumarate hydratase, mitochondrial (Dictyostelium discoideum)
relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum

[Term]
id: PR:P08417
name: fumarate hydratase, mitochondrial (yeast)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of yeast." [OMA:P08417, PANTHER:PTHR11444:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "yFH" EXACT PRO-short-label [PRO:DNx]
synonym: "FUM1" RELATED Gene-based [UniProtKB:P08417]
synonym: "YPL262W" RELATED Gene-based [UniProtKB:P08417]
synonym: "fumarase (yeast)" EXACT [UniProtKB:P08417]
xref: UniProtKB:P08417
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template SGD:S000006183 ! FUM1 (yeast)

[Term]
id: PR:O17214
name: probable fumarate hydratase, mitochondrial (worm)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of worm." [OMA:O17214, PANTHER:PTHR11444:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "fum-1" RELATED Gene-based [UniProtKB:O17214]
synonym: "H14A12.2" RELATED Gene-based [UniProtKB:O17214]
synonym: "FH (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarase (worm)" EXACT [UniProtKB:O17214]
xref: UniProtKB:O17214
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template WormBase:WBGene00001503 ! fum-1 (worm)

[Term]
id: PR:P14408-1
name: fumarate hydratase, mitochondrial isoform Mitochondrial (rat)
def: "A fumarate hydratase, mitochondrial (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14408-1." [PRO:DNx, UniProtKB:P14408]
comment: Category=organism-sequence.
synonym: "rFH/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14408-1
is_a: PR:P14408 ! fumarate hydratase, mitochondrial (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P14408-2
name: fumarate hydratase, mitochondrial isoform Cytoplasmic (rat)
def: "A fumarate hydratase, mitochondrial (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14408-2." [PRO:DNx, UniProtKB:P14408]
comment: Category=organism-sequence.
synonym: "rFH/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14408-2
is_a: PR:P14408 ! fumarate hydratase, mitochondrial (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000047418
name: fumarate hydratase, mitochondrial, transit peptide removed form (human)
def: "A fumarate hydratase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P07954, 45-510." [PRO:DNx, Reactome:R-HSA-70980]
comment: Category=organism-modification.
synonym: "hFH/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010319" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07954, 45-510" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-70980 "PR:000047418 located_in GO:0005759"
intersection_of: PR:P07954 ! fumarate hydratase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q54VA2
name: fumarate hydratase, mitochondrial (Dictyostelium discoideum)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54VA2, PANTHER:PTHR11444:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "fumH" RELATED Gene-based [UniProtKB:Q54VA2]
synonym: "Dicty-FH" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0280495" RELATED Gene-based [UniProtKB:Q54VA2]
synonym: "fumarase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54VA2]
xref: UniProtKB:Q54VA2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template dictyBase:DDB_G0280495 ! fumH (Dictyostelium discoideum)

[Term]
id: PR:P14408
name: fumarate hydratase, mitochondrial (rat)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of rat." [OMA:P14408, PANTHER:PTHR11444:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fh" RELATED Gene-based [UniProtKB:P14408]
synonym: "Fh1" RELATED Gene-based [UniProtKB:P14408]
synonym: "rFH" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarase (rat)" EXACT [UniProtKB:P14408]
xref: UniProtKB:P14408
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template RGD:2614 ! Fh (rat)

[Term]
id: PR:O94552
name: fumarate hydratase, mitochondrial (Schizosaccharomyces pombe 972h-)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O94552, PANTHER:PTHR11444:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "fum1" RELATED Gene-based [UniProtKB:O94552]
synonym: "SPCC18.18c" RELATED Gene-based [UniProtKB:O94552]
synonym: "SPCC290.01c" RELATED Gene-based [UniProtKB:O94552]
synonym: "Spom972h-FH" EXACT PRO-short-label [PRO:DNx]
synonym: "fumarase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O94552]
xref: UniProtKB:O94552
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template PomBase:SPCC18.18c ! fum1 (Schizosaccharomyces pombe)

[Term]
id: PR:P97807
name: fumarate hydratase, mitochondrial (mouse)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of mouse." [OMA:P97807, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fh" RELATED Gene-based [UniProtKB:P97807]
synonym: "Fh1" RELATED Gene-based [UniProtKB:P97807]
synonym: "mFH" EXACT PRO-short-label [PRO:DNx]
synonym: "EF-3 (mouse)" EXACT [UniProtKB:P97807]
synonym: "fumarase (mouse)" EXACT [UniProtKB:P97807]
xref: UniProtKB:P97807
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template MGI:95530 ! Fh1 (mouse)

[Term]
id: PR:Q7SX99
name: fumarate hydratase, mitochondrial (zebrafish)
def: "A fumarate hydratase, mitochondrial that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "fh" RELATED Gene-based [UniProtKB:Q7SX99]
synonym: "z-FH" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:66253" RELATED Gene-based [UniProtKB:Q7SX99]
synonym: "fumarase (zebrafish)" EXACT [UniProtKB:Q7SX99]
xref: UniProtKB:Q7SX99
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000007511 ! fumarate hydratase, mitochondrial
relationship: has_gene_template ZFIN:ZDB-GENE-010724-6 ! fh (zebrafish)