[Term] id: PR:000007597 name: protein c-Fos def: "A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. Requested by=CL. synonym: "FOS" EXACT PRO-short-label [PRO:DNx] synonym: "G0S7" RELATED Gene-based [] synonym: "cellular oncogene fos" EXACT [] synonym: "proto-oncogene protein c-fos" EXACT [] synonym: "G0/G1 switch regulatory protein 7" EXACT [] synonym: "transcription factor AP-1 subunit c-Fos" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P01100 name: protein c-Fos (human) def: "A protein c-Fos that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01100] comment: Category=organism-gene. synonym: "FOS" RELATED Gene-based [UniProtKB:P01100] synonym: "G0S7" RELATED Gene-based [UniProtKB:P01100] synonym: "hFOS" EXACT PRO-short-label [PRO:DNx] synonym: "proto-oncogene c-Fos (human)" EXACT [UniProtKB:P01100] synonym: "cellular oncogene fos (human)" EXACT [UniProtKB:P01100] synonym: "G0/G1 switch regulatory protein 7 (human)" EXACT [UniProtKB:P01100] synonym: "transcription factor AP-1 subunit c-Fos (human)" EXACT [UniProtKB:P01100] synonym: "Fos proto-oncogene, AP-1 transcription factor subunit (human)" EXACT [UniProtKB:P01100] xref: Reactome:R-HSA-450216 "PR:P01100 located_in GO:0005654" xref: UniProtKB:P01100 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007597 ! protein c-Fos relationship: has_gene_template HGNC:3796 ! FOS (human) [Term] id: PR:000047442 name: protein c-Fos phosphorylated 1 (human) def: "A protein c-Fos (human) that has been post-translationally modified to include phosphothreonine at positions 325 and 331, and phosphoserine at positions 362 and 374 of the amino acid sequence represented by UniProtKB:P01100. UniProtKB:P01100, Thr-325/Thr-331, MOD:00047|Ser-362/Ser-374, MOD:00046." [PRO:DNx, Reactome:R-HSA-450283] comment: Category=organism-modification. synonym: "hFOS/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01100, Thr-325/Thr-331, MOD:00047|Ser-362/Ser-374, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-450283 "PR:000047442 located_in GO:0005654" is_a: PR:P01100 ! protein c-Fos (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01100-2 name: protein c-Fos isoform h2 (human) def: "A protein c-Fos (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01100-2." [PRO:DNx, UniProtKB:P01100] comment: Category=organism-sequence. synonym: "hFOS/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01100-2 is_a: PR:P01100 ! protein c-Fos (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01100-3 name: protein c-Fos isoform h3 (human) def: "A protein c-Fos (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01100-3." [PRO:DNx, UniProtKB:P01100] comment: Category=organism-sequence. synonym: "hFOS/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01100-3 is_a: PR:P01100 ! protein c-Fos (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01100-1 name: protein c-Fos isoform 1 (human) def: "A protein c-Fos isoform 1 that is encoded in the genome of human." [PRO:CNx] comment: Category=organism-sequence. synonym: "hFOS/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01100-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026840 ! protein c-Fos isoform 1 [Term] id: PR:000026843 name: protein c-Fos isoform 1 phosphorylated 1 (human) def: "A protein c-Fos isoform 1 phosphorylated 1 in human. UniProtKB:P01100-1, Thr-325/Thr-331, MOD:00047|Ser-362/Ser-374, MOD:00046." [PMID:12134156, PRO:CNx, PRO:DAN] comment: Category=organism-modification. synonym: "hFOS/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01100-1, Thr-325/Thr-331, MOD:00047|Ser-362/Ser-374, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026842 ! protein c-Fos isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine