[Term]
id: PR:Q9WVH4
name: forkhead box protein O3 (mouse)
def: "A forkhead box protein O3 that is encoded in the genome of mouse." [OMA:Q9WVH4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fkhr2" RELATED Gene-based [UniProtKB:Q9WVH4]
synonym: "Foxo3" RELATED Gene-based [UniProtKB:Q9WVH4]
synonym: "Foxo3a" RELATED Gene-based [UniProtKB:Q9WVH4]
synonym: "mFOXO3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WVH4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007641 ! forkhead box protein O3
relationship: has_gene_template MGI:1890081 ! Foxo3 (mouse)

[Term]
id: PR:000045589
name: forkhead box protein O3 phosphorylated 1 (human)
def: "A forkhead box protein O3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-644 of the amino acid sequence represented by UniProtKB:O43524-1. Example: UniProtKB:O43524-1, Ser-644, MOD:00046." [PMID:23691078, iPTMnet:O43524]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23691078). Status=unreviewed.
synonym: "hFOXO3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43524-1, Ser-644, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O43524 ! forkhead box protein O3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43524
name: forkhead box protein O3 (human)
def: "A forkhead box protein O3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43524]
comment: Category=organism-gene.
synonym: "FOXO3" RELATED Gene-based [UniProtKB:O43524]
synonym: "FKHRL1" RELATED Gene-based [UniProtKB:O43524]
synonym: "FOXO3A" RELATED Gene-based [UniProtKB:O43524]
synonym: "hFOXO3" EXACT PRO-short-label [PRO:DNx]
synonym: "AF6q21 protein (human)" EXACT [UniProtKB:O43524]
synonym: "forkhead in rhabdomyosarcoma-like 1 (human)" EXACT [UniProtKB:O43524]
xref: Reactome:R-HSA-8870560 "PR:O43524 located_in GO:0005829"
xref: Reactome:R-HSA-8870627 "PR:O43524 located_in GO:0005654"
xref: UniProtKB:O43524
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007641 ! forkhead box protein O3
relationship: has_gene_template HGNC:3821 ! FOXO3 (human)

[Term]
id: PR:O43524-2
name: forkhead box protein O3 isoform h2 (human)
def: "A forkhead box protein O3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43524-2." [PRO:DNx, UniProtKB:O43524]
comment: Category=organism-sequence.
synonym: "hFOXO3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43524-2
is_a: PR:O43524 ! forkhead box protein O3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43524-1
name: forkhead box protein O3 isoform h1 (human)
def: "A forkhead box protein O3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43524-1." [PRO:DNx, UniProtKB:O43524]
comment: Category=organism-sequence.
synonym: "hFOXO3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43524-1
is_a: PR:O43524 ! forkhead box protein O3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000007641
name: forkhead box protein O3
def: "A protein that is a translation product of the human FOXO3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FOXO3" EXACT PRO-short-label [PRO:DNx]
synonym: "FKHRL1" RELATED Gene-based []
synonym: "FOXO3A" RELATED Gene-based []
synonym: "AF6q21 protein" EXACT []
synonym: "forkhead in rhabdomyosarcoma-like 1" EXACT []
is_a: PR:000000001 ! protein