[Term]
id: PR:Q9EQD0
name: frizzled-5 (mouse)
def: "A frizzled-5 that is encoded in the genome of mouse." [OMA:Q9EQD0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fzd5" RELATED Gene-based [UniProtKB:Q9EQD0]
synonym: "mFz5" EXACT [UniProtKB:Q9EQD0]
synonym: "mFZD5" EXACT PRO-short-label [PRO:DNx]
synonym: "Fz-5 (mouse)" EXACT [UniProtKB:Q9EQD0]
xref: UniProtKB:Q9EQD0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007721 ! frizzled-5
relationship: has_gene_template MGI:108571 ! Fzd5 (mouse)

[Term]
id: PR:000040435
name: frizzled-5 isoform 1
def: "A frizzled-5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13467-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "FZD5/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007721 ! frizzled-5

[Term]
id: PR:Q9EQD0-1
name: frizzled-5 isoform 1 (mouse)
def: "A frizzled-5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mFZD5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9EQD0-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040435 ! frizzled-5 isoform 1

[Term]
id: PR:Q13467-1
name: frizzled-5 isoform 1 (human)
def: "A frizzled-5 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hFZD5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13467-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040435 ! frizzled-5 isoform 1

[Term]
id: PR:Q13467
name: frizzled-5 (human)
def: "A frizzled-5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13467]
comment: Category=organism-gene.
synonym: "FZD5" RELATED Gene-based [UniProtKB:Q13467]
synonym: "hFz5" EXACT [UniProtKB:Q13467]
synonym: "hFZD5" EXACT PRO-short-label [PRO:DNx]
synonym: "C2orf31" RELATED Gene-based [UniProtKB:Q13467]
synonym: "Fz-5 (human)" EXACT [UniProtKB:Q13467]
synonym: "FzE5 (human)" EXACT [UniProtKB:Q13467]
xref: DTO:02100107
xref: UniProtKB:Q13467
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007721 ! frizzled-5
relationship: has_gene_template HGNC:4043 ! FZD5 (human)

[Term]
id: PR:Q1ZXI9
name: frizzled and smoothened-like protein O (Dictyostelium discoideum)
def: "A frizzled-5 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q1ZXI9, PRO:DNx]
comment: Category=organism-gene.
synonym: "fslO" RELATED Gene-based [UniProtKB:Q1ZXI9]
synonym: "Dicty-FZD5" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0278289" RELATED Gene-based [UniProtKB:Q1ZXI9]
xref: UniProtKB:Q1ZXI9
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000007721 ! frizzled-5
relationship: has_gene_template dictyBase:DDB_G0278289 ! fslO (Dictyostelium discoideum)

[Term]
id: PR:000047475
name: frizzled-5, signal peptide removed form (human)
def: "A frizzled-5 (human) that has had the signal peptide removed. UniProtKB:Q13467, 27-585." [PRO:DNx, Reactome:R-HSA-443952, Reactome:R-HSA-5140725, Reactome:R-HSA-5368467]
comment: Category=organism-modification.
synonym: "hFZD5/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012990" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13467, 27-585" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-443952 "PR:000047475 located_in GO:0005886"
xref: Reactome:R-HSA-5140725 "PR:000047475 located_in GO:0030669"
xref: Reactome:R-HSA-5368467 "PR:000047475 located_in GO:0031901"
intersection_of: PR:Q13467 ! frizzled-5 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047476
name: frizzled-5, signal peptide removed ubiquitinated form (human)
def: "A frizzled-5 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q13467, 27-585, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641190]
comment: Category=organism-modification.
synonym: "hFZD5/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012990, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13467, 27-585, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4641190 "PR:000047476 located_in GO:0005886"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q13467 ! frizzled-5 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8CHL0-1
name: frizzled-5 isoform 1 (rat)
def: "A frizzled-5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rFZD5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CHL0-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040435 ! frizzled-5 isoform 1

[Term]
id: PR:000057033
name: frizzled-5 O-glycosylated 1 (human)
def: "A frizzled-5 (human) that has been O-glycosylated at the residue equivalent to Thr-168 of the amino acid sequence represented by UniProtKB:Q13467-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q13467-1, Thr-168, MOD:00005~GNO:G43417UB." [GlyGen:Q13467-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hFZD5/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13467-1, Thr-168, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13467 ! frizzled-5 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000007721
name: frizzled-5
def: "A frizzled-like G-protein coupled receptor that is a translation product of the human FZD5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Fz5" EXACT []
synonym: "FZD5" EXACT PRO-short-label [PRO:DNx]
synonym: "Fz-5" EXACT []
synonym: "FzE5" EXACT []
synonym: "C2orf31" RELATED Gene-based []
xref: IUPHARobj:233
is_a: PR:000001315 ! frizzled-like G-protein coupled receptor

[Term]
id: PR:Q8CHL0
name: frizzled-5 (rat)
def: "A frizzled-5 that is encoded in the genome of rat." [OMA:Q8CHL0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fzd5" RELATED Gene-based [UniProtKB:Q8CHL0]
synonym: "rFZD5" EXACT PRO-short-label [PRO:DNx]
synonym: "Fz-5 (rat)" EXACT [UniProtKB:Q8CHL0]
xref: UniProtKB:Q8CHL0
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007721 ! frizzled-5
relationship: has_gene_template RGD:631406 ! Fzd5 (rat)