[Term] id: PR:P30793-4 name: GTP cyclohydrolase 1 isoform hGCH-4 (human) def: "A GTP cyclohydrolase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30793-4." [PRO:DNx, UniProtKB:P30793] comment: Category=organism-sequence. synonym: "hGCH1/iso:hGCH-4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P30793-4 is_a: PR:P30793 ! GTP cyclohydrolase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P30793 name: GTP cyclohydrolase 1 (human) def: "A GTP cyclohydrolase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P30793] comment: Category=organism-gene. synonym: "GCH" RELATED Gene-based [UniProtKB:P30793] synonym: "DYT5" RELATED Gene-based [UniProtKB:P30793] synonym: "GCH1" RELATED Gene-based [UniProtKB:P30793] synonym: "hGCH1" EXACT PRO-short-label [PRO:DNx] synonym: "GTP-CH-I (human)" EXACT [UniProtKB:P30793] synonym: "GTP cyclohydrolase I (human)" EXACT [UniProtKB:P30793] xref: Reactome:R-HSA-1474127 "PR:P30793 located_in GO:0005829" xref: UniProtKB:P30793 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007893 ! GTP cyclohydrolase 1 relationship: has_gene_template HGNC:4193 ! GCH1 (human) [Term] id: PR:P30793-1 name: GTP cyclohydrolase 1 isoform hGCH-1 (human) def: "A GTP cyclohydrolase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30793-1." [PRO:DNx, UniProtKB:P30793] comment: Category=organism-sequence. synonym: "hGCH1/iso:hGCH-1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P30793-1 is_a: PR:P30793 ! GTP cyclohydrolase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P30793-2 name: GTP cyclohydrolase 1 isoform hGCH-2 (human) def: "A GTP cyclohydrolase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30793-2." [PRO:DNx, UniProtKB:P30793] comment: Category=organism-sequence. synonym: "hGCH1/iso:hGCH-2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P30793-2 is_a: PR:P30793 ! GTP cyclohydrolase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P30793-3 name: GTP cyclohydrolase 1 isoform hGCH-3 (human) def: "A GTP cyclohydrolase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30793-3." [PRO:DNx, UniProtKB:P30793] comment: Category=organism-sequence. synonym: "hGCH1/iso:hGCH-3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P30793-3 is_a: PR:P30793 ! GTP cyclohydrolase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045748 name: GTP cyclohydrolase 1 phosphorylated 1 (human) def: "A GTP cyclohydrolase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-81 of the amino acid sequence represented by UniProtKB:P30793-1. Example: UniProtKB:P30793-1, Ser-81, MOD:00046." [PMID:17704208, iPTMnet:P30793] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17704208). Status=unreviewed. synonym: "hGCH1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P30793-1, Ser-81, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P30793 ! GTP cyclohydrolase 1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000007893 name: GTP cyclohydrolase 1 def: "A protein that is a translation product of the human GCH1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "GCH" RELATED Gene-based [] synonym: "DYT5" RELATED Gene-based [] synonym: "GCH1" EXACT PRO-short-label [PRO:DNx] synonym: "GTP-CH-I" BROAD [PRO:DNx] synonym: "GTP cyclohydrolase I" BROAD [PRO:DNx] is_a: PR:000000001 ! protein