[Term] id: PR:000019994 name: growth hormone receptor, signal peptide removed form def: "A growth hormone receptor that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "GHR/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000007970 ! growth hormone receptor intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000019995 name: growth hormone receptor proteolytic cleavage product def: "A growth hormone receptor that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "GHR/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000007970 ! growth hormone receptor [Term] id: PR:P10912 name: growth hormone receptor (human) def: "A growth hormone receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10912] comment: Category=organism-gene. synonym: "GHR" RELATED Gene-based [UniProtKB:P10912] synonym: "hGHR" EXACT PRO-short-label [PRO:DNx] synonym: "GH receptor (human)" EXACT [UniProtKB:P10912] synonym: "somatotropin receptor (human)" EXACT [UniProtKB:P10912] xref: UniProtKB:P10912 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007970 ! growth hormone receptor relationship: has_gene_template HGNC:4263 ! GHR (human) [Term] id: PR:P16310-1 name: growth hormone receptor isoform r1 (rat) def: "A growth hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16310-1." [PRO:DNx, UniProtKB:P16310] comment: Category=organism-sequence. synonym: "rGHR/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16310-1 is_a: PR:P16310 ! growth hormone receptor (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P10912-3 name: growth hormone receptor isoform h3 (human) def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-3." [PRO:DNx, UniProtKB:P10912] comment: Category=organism-sequence. synonym: "hGHR/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHR1-277 (human)" EXACT [UniProtKB:P10912] xref: UniProtKB:P10912-3 is_a: PR:P10912 ! growth hormone receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P10912-2 name: growth hormone receptor isoform h2 (human) def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-2." [PRO:DNx, UniProtKB:P10912] comment: Category=organism-sequence. synonym: "hGHR/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHRtr (human)" EXACT [UniProtKB:P10912] synonym: "growth hormone receptor isoform GHR1-279 (human)" EXACT [UniProtKB:P10912] xref: UniProtKB:P10912-2 is_a: PR:P10912 ! growth hormone receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16882 name: growth hormone receptor (mouse) def: "A growth hormone receptor that is encoded in the genome of mouse." [OMA:P16882, PRO:DNx] comment: Category=organism-gene. synonym: "Ghr" RELATED Gene-based [UniProtKB:P16882] synonym: "mGHR" EXACT PRO-short-label [PRO:DNx] synonym: "GH receptor (mouse)" EXACT [UniProtKB:P16882] synonym: "somatotropin receptor (mouse)" EXACT [UniProtKB:P16882] xref: UniProtKB:P16882 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007970 ! growth hormone receptor relationship: has_gene_template MGI:95708 ! Ghr (mouse) [Term] id: PR:000007970 name: growth hormone receptor def: "A protein that is a translation product of the human GHR gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "GHR" EXACT PRO-short-label [PRO:DNx] synonym: "GH receptor" EXACT [] synonym: "somatotropin receptor" EXACT [] xref: IUPHARobj:1720 is_a: PR:000000001 ! protein [Term] id: PR:000047529 name: growth hormone receptor, signal peptide removed form (human) def: "A growth hormone receptor (human) that has had the signal peptide removed. UniProtKB:P10912, 19-638." [PRO:DNx, Reactome:R-HSA-1169263] comment: Category=organism-modification. synonym: "hGHR/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000010957" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P10912, 19-638" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-982779 "PR:000047529 located_in GO:0005886" xref: Reactome:R-HSA-1168385 "PR:000047529 located_in GO:0005886" xref: Reactome:R-HSA-1169263 "PR:000047529 located_in GO:0031904" intersection_of: PR:P10912 ! growth hormone receptor (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047531 name: growth hormone receptor, signal peptide removed phosphorylated 2 (human) def: "A growth hormone receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 332, 487 and 627 of the amino acid sequence represented by UniProtKB:P10912. UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-627, MOD:00048." [PRO:DNx, Reactome:R-HSA-1169226] comment: Category=organism-modification. synonym: "hGHR/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000010957, Tyr-332/Tyr-487/Tyr-627, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-627, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1169226 "PR:000047531 located_in GO:0005886" is_a: PR:P10912 ! growth hormone receptor (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000047530 name: growth hormone receptor, signal peptide removed phosphorylated 1 (human) def: "A growth hormone receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 332, 487, 534, 566 and 627 of the amino acid sequence represented by UniProtKB:P10912. UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048." [PRO:DNx, Reactome:R-HSA-1168904] comment: Category=organism-modification. synonym: "hGHR/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000010957, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1168904 "PR:000047530 located_in GO:0005886" is_a: PR:P10912 ! growth hormone receptor (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P16882-1 name: growth hormone receptor isoform m1 (mouse) def: "A growth hormone receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16882-1." [PRO:DNx, UniProtKB:P16882] comment: Category=organism-sequence. synonym: "mGHR/iso:m1" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform HMW GHR (mouse)" EXACT [UniProtKB:P16882] xref: UniProtKB:P16882-1 is_a: PR:P16882 ! growth hormone receptor (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P10912-1 name: growth hormone receptor isoform h1 (human) def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-1." [PRO:DNx, UniProtKB:P10912] comment: Category=organism-sequence. synonym: "hGHR/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHRfl (human)" EXACT [UniProtKB:P10912] xref: UniProtKB:P10912-1 is_a: PR:P10912 ! growth hormone receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16310 name: growth hormone receptor (rat) def: "A growth hormone receptor that is encoded in the genome of rat." [OMA:P16310, PANTHER:PTHR23036:SF21, PRO:DNx] comment: Category=organism-gene. synonym: "Ghr" RELATED Gene-based [UniProtKB:P16310] synonym: "rGHR" EXACT PRO-short-label [PRO:DNx] synonym: "GH receptor (rat)" EXACT [UniProtKB:P16310] synonym: "somatotropin receptor (rat)" EXACT [UniProtKB:P16310] xref: UniProtKB:P16310 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000007970 ! growth hormone receptor relationship: has_gene_template RGD:2687 ! Ghr (rat) [Term] id: PR:P16882-2 name: growth hormone receptor isoform m2 (mouse) def: "A growth hormone receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16882-2." [PRO:DNx, UniProtKB:P16882] comment: Category=organism-sequence. synonym: "mGHR/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHBP (mouse)" EXACT [UniProtKB:P16882] synonym: "growth hormone receptor isoform LMW GHR (mouse)" EXACT [UniProtKB:P16882] xref: UniProtKB:P16882-2 is_a: PR:P16882 ! growth hormone receptor (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P10912-4 name: growth hormone receptor isoform h4 (human) def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-4." [PRO:DNx, UniProtKB:P10912] comment: Category=organism-sequence. synonym: "hGHR/iso:h4" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHRd3 (human)" EXACT [UniProtKB:P10912] xref: UniProtKB:P10912-4 is_a: PR:P10912 ! growth hormone receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q02092 name: growth hormone receptor (chicken) def: "A growth hormone receptor that is encoded in the genome of chicken." [OMA:Q02092, PANTHER:PTHR23036:SF21, PRO:DNx] comment: Category=organism-gene. synonym: "GHR" RELATED Gene-based [UniProtKB:Q02092] synonym: "chick-GHR" EXACT PRO-short-label [PRO:DNx] synonym: "GH receptor (chicken)" EXACT [UniProtKB:Q02092] synonym: "somatotropin receptor (chicken)" EXACT [UniProtKB:Q02092] xref: UniProtKB:Q02092 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000007970 ! growth hormone receptor relationship: has_gene_template NCBIGene:408184 ! GHR (chicken) [Term] id: PR:P16310-2 name: growth hormone receptor isoform r2 (rat) def: "A growth hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16310-2." [PRO:DNx, UniProtKB:P16310] comment: Category=organism-sequence. synonym: "rGHR/iso:r2" EXACT PRO-short-label [PRO:DNx] synonym: "growth hormone receptor isoform GHBP (rat)" EXACT [UniProtKB:P16310] synonym: "growth hormone receptor isoform Short from (rat)" EXACT [UniProtKB:P16310] xref: UniProtKB:P16310-2 is_a: PR:P16310 ! growth hormone receptor (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus