[Term]
id: PR:000047548
name: transcriptional activator GLI3 phosphorylated 1 (human)
def: "A transcriptional activator GLI3 (human) that has been post-translationally modified to include phosphoserine at positions 849, 865, 877, 907, 980 and 1006 of the amino acid sequence represented by UniProtKB:P10071. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610492]
comment: Category=organism-modification.
synonym: "hGLI3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5610492 "PR:000047548 located_in GO:0097546"
is_a: PR:P10071 ! transcriptional activator GLI3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047549
name: transcriptional activator GLI3 phosphorylated form (human)
def: "A transcriptional activator GLI3 (human) that includes at least one phosphorylated residue. UniProtKB:P10071, MOD:00696." [PRO:DNx, Reactome:R-HSA-5635048]
comment: Category=organism-modification.
synonym: "hGLI3/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10071, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5635048 "PR:000047549 located_in GO:0097542"
xref: Reactome:R-HSA-5635051 "PR:000047549 located_in GO:0005654"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:P10071 ! transcriptional activator GLI3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047550
name: transcriptional activator GLI3 phosphorylated and ubiquitinated form (human)
def: "A transcriptional activator GLI3 (human) that includes at least one phosphorylated residue and at least one ubiquitinated lysine. UniProtKB:P10071, MOD:00696|MOD:01148." [PRO:DNx, Reactome:R-HSA-5635060]
comment: Category=organism-modification.
synonym: "hGLI3/PhosUbiq+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10071, MOD:00696|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5635060 "PR:000047550 located_in GO:0005654"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:P10071 ! transcriptional activator GLI3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008028
name: transcriptional activator GLI3
def: "A GLI protein that is a translation product of the human GLI3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GLI3" EXACT PRO-short-label [PRO:DNx]
synonym: "GLI3FL" EXACT []
synonym: "GLI3-190" BROAD []
synonym: "GLI3 form of 190 kDa" EXACT []
synonym: "GLI3 full-length protein" EXACT []
synonym: "zinc finger protein GLI3" EXACT []
is_a: PR:000050018 ! GLI protein

[Term]
id: PR:P10071
name: transcriptional activator GLI3 (human)
def: "A transcriptional activator GLI3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10071]
comment: Category=organism-gene.
synonym: "GLI3" RELATED Gene-based [UniProtKB:P10071]
synonym: "hGLI3" EXACT PRO-short-label [PRO:DNx]
synonym: "GLI3FL (human)" EXACT [UniProtKB:P10071]
synonym: "GLI3-190 (human)" EXACT [UniProtKB:P10071]
synonym: "GLI3 form of 190 kDa (human)" EXACT [UniProtKB:P10071]
synonym: "GLI3 full-length protein (human)" EXACT [UniProtKB:P10071]
xref: Reactome:R-HSA-206085 "PR:P10071 located_in GO:0005829"
xref: Reactome:R-HSA-5610365 "PR:P10071 located_in GO:0097546"
xref: Reactome:R-HSA-5610367 "PR:P10071 located_in GO:0097542"
xref: UniProtKB:P10071
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008028 ! transcriptional activator GLI3
relationship: has_gene_template HGNC:4319 ! GLI3 (human)