[Term]
id: PR:000047566
name: GDP-mannose 4,6 dehydratase, initiator methionine removed form (human)
def: "A GDP-mannose 4,6 dehydratase (human) that has had the initiator methionine removed. UniProtKB:O60547, 2-372." [PRO:DNx, Reactome:R-HSA-6787620]
comment: Category=organism-modification.
synonym: "PRO_0000201705" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGMDS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O60547, 2-372" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6787620 "PR:000047566 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:O60547 ! GDP-mannose 4,6 dehydratase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O60547
name: GDP-mannose 4,6 dehydratase (human)
def: "A GDP-mannose 4,6 dehydratase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60547]
comment: Category=organism-gene.
synonym: "GMDS" RELATED Gene-based [UniProtKB:O60547]
synonym: "hGMDS" EXACT PRO-short-label [PRO:DNx]
synonym: "GMD (human)" EXACT [UniProtKB:O60547]
synonym: "GDP-D-mannose dehydratase (human)" EXACT [UniProtKB:O60547]
xref: UniProtKB:O60547
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008067 ! GDP-mannose 4,6 dehydratase
relationship: has_gene_template HGNC:4369 ! GMDS (human)

[Term]
id: PR:O60547-1
name: GDP-mannose 4,6 dehydratase isoform 1 (human)
def: "A GDP-mannose 4,6 dehydratase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGMDS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60547-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038258 ! GDP-mannose 4,6 dehydratase isoform 1

[Term]
id: PR:000008067
name: GDP-mannose 4,6 dehydratase
def: "A protein that is a translation product of the human GMDS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GMD" EXACT []
synonym: "GMDS" EXACT PRO-short-label [PRO:DNx]
synonym: "GDP-D-mannose dehydratase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:O60547-2
name: GDP-mannose 4,6 dehydratase isoform h2 (human)
def: "A GDP-mannose 4,6 dehydratase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60547-2." [PRO:DNx, UniProtKB:O60547]
comment: Category=organism-sequence.
synonym: "hGMDS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60547-2
is_a: PR:O60547 ! GDP-mannose 4,6 dehydratase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens