[Term]
id: PR:Q14956-2
name: transmembrane glycoprotein NMB isoform h2 (human)
def: "A transmembrane glycoprotein NMB (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14956-2." [PRO:DNx, UniProtKB:Q14956]
comment: Category=organism-sequence.
synonym: "hGPNMB/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14956-2
is_a: PR:Q14956 ! transmembrane glycoprotein NMB (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14956-1
name: transmembrane glycoprotein NMB isoform h1 (human)
def: "A transmembrane glycoprotein NMB (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14956-1." [PRO:DNx, UniProtKB:Q14956]
comment: Category=organism-sequence.
synonym: "hGPNMB/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14956-1
is_a: PR:Q14956 ! transmembrane glycoprotein NMB (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000008183
name: transmembrane glycoprotein NMB
def: "A protein that is a translation product of the human GPNMB gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NMB" RELATED Gene-based []
synonym: "Dchil" RELATED Gene-based []
synonym: "GPNMB" EXACT PRO-short-label [PRO:DNx]
synonym: "HGFIN" RELATED Gene-based []
synonym: "DC-HIL" EXACT []
synonym: "UNQ1725/PRO9925" RELATED Gene-based []
synonym: "transmembrane glycoprotein HGFIN" EXACT []
synonym: "dendritic cell-associated transmembrane protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q14956
name: transmembrane glycoprotein NMB (human)
def: "A transmembrane glycoprotein NMB that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14956]
comment: Category=organism-gene.
synonym: "NMB" RELATED Gene-based [UniProtKB:Q14956]
synonym: "GPNMB" RELATED Gene-based [UniProtKB:Q14956]
synonym: "HGFIN" RELATED Gene-based [UniProtKB:Q14956]
synonym: "hGPNMB" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ1725/PRO9925" RELATED Gene-based [UniProtKB:Q14956]
synonym: "hematopoietic growth factor inducible neurokinin-1 type (human)" EXACT [UniProtKB:Q14956]
xref: UniProtKB:Q14956
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008183 ! transmembrane glycoprotein NMB
relationship: has_gene_template HGNC:4462 ! GPNMB (human)

[Term]
id: PR:000047599
name: transmembrane glycoprotein NMB, signal peptide removed phosphorylated 1 (human)
def: "A transmembrane glycoprotein NMB (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at position 525 of the amino acid sequence represented by UniProtKB:Q14956. UniProtKB:Q14956, 22-572, Tyr-525, MOD:00048." [PRO:DNx, Reactome:R-HSA-8857558]
comment: Category=organism-modification.
synonym: "hGPNMB/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000024709, Tyr-525, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q14956, 22-572, Tyr-525, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8857558 "PR:000047599 located_in GO:0005886"
is_a: PR:Q14956 ! transmembrane glycoprotein NMB (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide