[Term]
id: PR:P24298
name: alanine aminotransferase 1 (human)
def: "An alanine aminotransferase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P24298]
comment: Category=organism-gene.
synonym: "GPT" RELATED Gene-based [UniProtKB:P24298]
synonym: "AAT1" RELATED Gene-based [UniProtKB:P24298]
synonym: "GPT1" RELATED Gene-based [UniProtKB:P24298]
synonym: "hGPT" EXACT PRO-short-label [PRO:DNx]
synonym: "ALT1 (human)" EXACT [UniProtKB:P24298]
synonym: "GPT 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamic--alanine transaminase 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamic--pyruvic transaminase 1 (human)" EXACT [UniProtKB:P24298]
synonym: "glutamate pyruvate transaminase 1 (human)" EXACT [UniProtKB:P24298]
xref: UniProtKB:P24298
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008208 ! alanine aminotransferase 1
relationship: has_gene_template HGNC:4552 ! GPT (human)

[Term]
id: PR:000008208
name: alanine aminotransferase 1
def: "An alanine aminotransferase that is a translation product of the human GPT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "GPT" EXACT PRO-short-label [PRO:DNx]
synonym: "AAT1" RELATED Gene-based []
synonym: "ALAT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "ALT1" EXACT []
synonym: "GPT1" RELATED Gene-based []
synonym: "SGPT" BROAD [Wikipedia:Alanine_transaminase]
synonym: "GPT 1" EXACT []
synonym: "alanine transaminase" BROAD [Wikipedia:Alanine_transaminase]
synonym: "glutamic--alanine transaminase 1" EXACT []
synonym: "glutamic--pyruvic transaminase 1" EXACT []
synonym: "glutamate pyruvate transaminase 1" EXACT []
synonym: "serum glutamic-pyruvic transaminase" BROAD [Wikipedia:Alanine_transaminase]
synonym: "serum glutamate-pyruvate transaminase" BROAD [Wikipedia:Alanine_transaminase]
is_a: PR:000050219 ! alanine aminotransferase

[Term]
id: PR:000047605
name: alanine aminotransferase 1, initiator methionine removed pyridoxal phosphate lysine 1 (human)
def: "An alanine aminotransferase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include pyridoxal phosphate lysine at position 314 of the amino acid sequence represented by UniProtKB:P24298. UniProtKB:P24298, 2-496, Lys-314, MOD:00128." [PRO:DNx, Reactome:R-HSA-70520]
comment: Category=organism-modification.
synonym: "hGPT/InitMet-/Pyrdox:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000123933, Lys-314, MOD:00128" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P24298, 2-496, Lys-314, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-70520 "PR:000047605 located_in GO:0005829"
is_a: PR:P24298 ! alanine aminotransferase 1 (human)
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000035943
name: alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1 (human)
def: "An alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1 in human. UniProtKB:P24298, 2-496, Ala-2, MOD:00050|Lys-314, MOD:00128." [PMID:1931970]
comment: Category=organism-modification.
synonym: "hGPT" RELATED [PMID:1931970]
synonym: "hGPT/InitMet-/AcPyrdox:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P24298, 2-496, Ala-2, MOD:00050|Lys-314, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035942 ! alanine aminotransferase 1, initiator methionine removed acetylated and pyridoxal phosphate lysine 1
relationship: has_part MOD:00050 ! N-acetyl-L-alanine
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine

[Term]
id: PR:P24298-1
name: alanine aminotransferase 1 isoform 1 (human)
def: "An alanine aminotransferase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGPT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24298-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039110 ! alanine aminotransferase 1 isoform 1