[Term]
id: PR:Q05586
name: glutamate receptor ionotropic, NMDA 1 (human)
def: "A glutamate receptor ionotropic, NMDA 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q05586]
comment: Category=organism-gene.
synonym: "GRIN1" RELATED Gene-based [UniProtKB:Q05586]
synonym: "NMDAR1" RELATED Gene-based [UniProtKB:Q05586]
synonym: "hGRIN1" EXACT PRO-short-label [PRO:DNx]
synonym: "GluN1 (human)" EXACT [UniProtKB:Q05586]
synonym: "NMD-R1 (human)" EXACT [UniProtKB:Q05586]
synonym: "glutamate [NMDA] receptor subunit zeta-1 (human)" EXACT [UniProtKB:Q05586]
synonym: "N-methyl-D-aspartate receptor subunit NR1 (human)" EXACT [UniProtKB:Q05586]
xref: DTO:01100261
xref: UniProtKB:Q05586
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008245 ! glutamate receptor ionotropic, NMDA 1
relationship: has_gene_template HGNC:4584 ! GRIN1 (human)

[Term]
id: PR:000008245
name: glutamate receptor ionotropic, NMDA 1
def: "An ionotropic glutamate receptor protein that is a translation product of the human GRIN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GRIN1" EXACT PRO-short-label [PRO:DNx]
synonym: "GluN1" EXACT []
synonym: "Glurz1" RELATED Gene-based []
synonym: "NMD-R1" EXACT []
synonym: "NMDAR1" RELATED Gene-based []
synonym: "glutamate [NMDA] receptor subunit zeta-1" EXACT []
synonym: "N-methyl-D-aspartate receptor subunit NR1" EXACT []
xref: IUPHARobj:455
is_a: PR:000044666 ! ionotropic glutamate receptor protein

[Term]
id: PR:Q05586-2
name: glutamate receptor ionotropic, NMDA 1 isoform short (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform short that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q05586]
comment: Category=organism-sequence. Note: In UniProtKB this form is called isoform 1.
synonym: "NR1-1 (human)" EXACT []
synonym: "hGRIN1/iso:short" EXACT PRO-short-label [PRO:DNx]
synonym: "glutamate receptor ionotropic, NMDA 1 isoform 1 (human)" EXACT [UniProtKB:Q05586]
xref: UniProtKB:Q05586-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037442 ! glutamate receptor ionotropic, NMDA 1 isoform short

[Term]
id: PR:Q05586-7
name: glutamate receptor ionotropic, NMDA 1 isoform 7 (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform 7 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGRIN1/iso:7" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05586-7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040288 ! glutamate receptor ionotropic, NMDA 1 isoform 7

[Term]
id: PR:Q05586-6
name: glutamate receptor ionotropic, NMDA 1 isoform h6 (human)
def: "A glutamate receptor ionotropic, NMDA 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05586-6." [PRO:DNx, UniProtKB:Q05586]
comment: Category=organism-sequence.
synonym: "hGRIN1/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05586-6
is_a: PR:Q05586 ! glutamate receptor ionotropic, NMDA 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q05586-5
name: glutamate receptor ionotropic, NMDA 1 isoform 5 (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform 5 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGRIN1/iso:5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05586-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040287 ! glutamate receptor ionotropic, NMDA 1 isoform 5

[Term]
id: PR:Q05586-4
name: glutamate receptor ionotropic, NMDA 1 isoform 4 (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform 4 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGRIN1/iso:4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05586-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040286 ! glutamate receptor ionotropic, NMDA 1 isoform 4

[Term]
id: PR:Q05586-3
name: glutamate receptor ionotropic, NMDA 1 isoform medium (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform medium that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence. Note: In UniProtKB this form is called isoform 2.
synonym: "hGRIN1/iso:medium" EXACT PRO-short-label [PRO:DNx]
synonym: "glutamate receptor ionotropic, NMDA 1 isoform 2 (human)" EXACT [UniProtKB:Q05586]
synonym: "glutamate receptor ionotropic, NMDA 1 isoform NR1-2 (human)" EXACT [UniProtKB:Q05586]
xref: UniProtKB:Q05586-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040285 ! glutamate receptor ionotropic, NMDA 1 isoform medium

[Term]
id: PR:000047620
name: glutamate receptor ionotropic, NMDA 1, signal peptide removed form (human)
def: "A glutamate receptor ionotropic, NMDA 1 (human) that has had the signal peptide removed. UniProtKB:Q05586, 19-938." [PRO:DNx, Reactome:R-HSA-419564]
comment: Category=organism-modification.
synonym: "PRO_0000011587" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGRIN1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q05586, 19-938" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-419564 "PR:000047620 located_in GO:0005886"
xref: Reactome:R-HSA-9609763 "PR:000047620 located_in GO:0005789"
xref: Reactome:R-HSA-9610565 "PR:000047620 located_in GO:0030658"
intersection_of: PR:Q05586 ! glutamate receptor ionotropic, NMDA 1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q05586-1
name: glutamate receptor ionotropic, NMDA 1 isoform long (human)
def: "A glutamate receptor ionotropic, NMDA 1 isoform long that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q05586]
comment: Category=organism-sequence. Note: In UniProtKB this form is called isoform 3.
synonym: "NR1-3 (human)" EXACT []
synonym: "hGRIN1/iso:long" EXACT PRO-short-label [PRO:DNx]
synonym: "glutamate receptor ionotropic, NMDA 1 isoform 3 (human)" EXACT [UniProtKB:Q05586]
xref: UniProtKB:Q05586-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037441 ! glutamate receptor ionotropic, NMDA 1 isoform long