[Term]
id: PR:000008247
name: glutamate receptor ionotropic, NMDA 2B
def: "An ionotropic glutamate receptor protein that is a translation product of the human GRIN2B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NR3" EXACT []
synonym: "NR2B" EXACT []
synonym: "GRIN2B" EXACT PRO-short-label [PRO:DNx]
synonym: "GluN2B" EXACT []
synonym: "NMDAR2B" RELATED Gene-based []
synonym: "N-methyl-D-aspartate receptor subunit 3" EXACT []
synonym: "N-methyl D-aspartate receptor subtype 2B" EXACT []
synonym: "glutamate [NMDA] receptor subunit epsilon-2" EXACT []
xref: IUPHARobj:457
is_a: PR:000044666 ! ionotropic glutamate receptor protein

[Term]
id: PR:Q13224
name: glutamate receptor ionotropic, NMDA 2B (human)
def: "A glutamate receptor ionotropic, NMDA 2B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13224]
comment: Category=organism-gene.
synonym: "hNR3" EXACT [UniProtKB:Q13224]
synonym: "GRIN2B" RELATED Gene-based [UniProtKB:Q13224]
synonym: "NMDAR2B" RELATED Gene-based [UniProtKB:Q13224]
synonym: "hGRIN2B" EXACT PRO-short-label [PRO:DNx]
synonym: "NR3 (human)" EXACT [UniProtKB:Q13224]
synonym: "NR2B (human)" EXACT [UniProtKB:Q13224]
synonym: "GluN2B (human)" EXACT [UniProtKB:Q13224]
synonym: "N-methyl-D-aspartate receptor subunit 3 (human)" EXACT [UniProtKB:Q13224]
synonym: "N-methyl D-aspartate receptor subtype 2B (human)" EXACT [UniProtKB:Q13224]
synonym: "glutamate [NMDA] receptor subunit epsilon-2 (human)" EXACT [UniProtKB:Q13224]
xref: DTO:01100258
xref: UniProtKB:Q13224
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008247 ! glutamate receptor ionotropic, NMDA 2B
relationship: has_gene_template HGNC:4586 ! GRIN2B (human)

[Term]
id: PR:000047623
name: glutamate receptor ionotropic, NMDA 2B, signal peptide removed phosphorylated 1 (human)
def: "A glutamate receptor ionotropic, NMDA 2B (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 1252, 1336 and 1474 of the amino acid sequence represented by UniProtKB:Q13224. UniProtKB:Q13224, 27-1484, Tyr-1252/Tyr-1336/Tyr-1474, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928477]
comment: Category=organism-modification.
synonym: "hGRIN2B/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000011577, Tyr-1252/Tyr-1336/Tyr-1474, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13224, 27-1484, Tyr-1252/Tyr-1336/Tyr-1474, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928477 "PR:000047623 located_in GO:0005886"
is_a: PR:Q13224 ! glutamate receptor ionotropic, NMDA 2B (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000047622
name: glutamate receptor ionotropic, NMDA 2B, signal peptide removed form (human)
def: "A glutamate receptor ionotropic, NMDA 2B (human) that has had the signal peptide removed. UniProtKB:Q13224, 27-1484." [PRO:DNx, Reactome:R-HSA-419558]
comment: Category=organism-modification.
synonym: "PRO_0000011577" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGRIN2B/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13224, 27-1484" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-419558 "PR:000047622 located_in GO:0005886"
xref: Reactome:R-HSA-9609765 "PR:000047622 located_in GO:0005789"
xref: Reactome:R-HSA-9610568 "PR:000047622 located_in GO:0030658"
intersection_of: PR:Q13224 ! glutamate receptor ionotropic, NMDA 2B (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens