[Term]
id: PR:P16403
name: histone H1.2 (human)
def: "A histone H1.2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16403]
comment: Category=organism-gene.
synonym: "H1-2" RELATED Gene-based [UniProtKB:P16403]
synonym: "H1F2" RELATED Gene-based [UniProtKB:P16403]
synonym: "hH1-2" EXACT PRO-short-label [PRO:DNx]
synonym: "HIST1H1C" RELATED Gene-based [UniProtKB:P16403]
synonym: "histone H1c (human)" BROAD [UniProtKB:P16403]
synonym: "histone H1d (human)" EXACT [UniProtKB:P16403]
synonym: "histone H1s-1 (human)" EXACT [UniProtKB:P16403]
xref: UniProtKB:P16403
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008576 ! histone H1.2
relationship: has_gene_template HGNC:4716 ! H1-2 (human)

[Term]
id: PR:000044871
name: histone H1.2, initiator methionine removed phosphorylated 3 (human)
def: "A histone H1.2 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-146 of the amino acid sequence represented by UniProtKB:P16403. UniProtKB:P16403, 2-213, Thr-146, MOD:00047." [HIstome_var_Hs:Histone_H1.2, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.2:H1T145ph" BROAD [HIstome_ptm_Hs:H1T145ph]
synonym: "hHIST1H1C/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16403, 2-213, Thr-146, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16403 ! histone H1.2 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044870
name: histone H1.2, initiator methionine removed phosphorylated 2 (human)
def: "A histone H1.2 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-173 of the amino acid sequence represented by UniProtKB:P16403. UniProtKB:P16403, 2-213, Ser-173, MOD:00046." [HIstome_var_Hs:Histone_H1.2, PMID:16377619, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.2:H1S172ph" BROAD [HIstome_ptm_Hs:H1S172ph]
synonym: "hHIST1H1C/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16403, 2-213, Ser-173, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16403 ! histone H1.2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000047700
name: histone H1.2, initiator methionine removed form (human)
def: "A histone H1.2 (human) that has had the initiator methionine removed. UniProtKB:P16403, 2-213." [PRO:DNx, Reactome:R-HSA-211237]
comment: Category=organism-modification.
synonym: "PRO_0000195906" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHIST1H1C/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16403, 2-213" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-211237 "PR:000047700 located_in GO:0005654"
xref: TDR:14061
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P16403 ! histone H1.2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000044868
name: histone H1.2, initiator methionine removed monomethylated 1 (human)
def: "A histone H1.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-187 of the amino acid sequence represented by UniProtKB:P16403. UniProtKB:P16403, 2-213, Lys-187, MOD:00085." [HIstome_var_Hs:Histone_H1.2, PMID:20334638, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.2:H1K186me1" BROAD [HIstome_ptm_Hs:H1K186me1]
synonym: "hHIST1H1C/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16403, 2-213, Lys-187, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16403 ! histone H1.2 (human)
relationship: has_part MOD:00085 ! N6-methyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000044869
name: histone H1.2, initiator methionine removed phosphorylated 1 (human)
def: "A histone H1.2 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-31 of the amino acid sequence represented by UniProtKB:P16403. UniProtKB:P16403, 2-213, Thr-31, MOD:00047." [HIstome_var_Hs:Histone_H1.2, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H1.2:H1T30ph" BROAD [HIstome_ptm_Hs:H1T30ph]
synonym: "hHIST1H1C/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16403, 2-213, Thr-31, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P16403 ! histone H1.2 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000008576
name: histone H1.2
def: "A histone H1 that is a translation product of the human H1-2 gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "H1c" EXACT []
synonym: "H1-2" EXACT PRO-short-label [PRO:DNx]
synonym: "H1F2" RELATED Gene-based []
synonym: "H1 VAR.1" EXACT []
synonym: "HIST1H1C" RELATED Gene-based []
synonym: "histone H1d" EXACT []
is_a: PR:000038372 ! histone H1