[Term] id: PR:P22791 name: hydroxymethylglutaryl-CoA synthase, mitochondrial (rat) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial that is encoded in the genome of rat." [OMA:P22791, PANTHER:PTHR11877:SF10, PRO:DNx] comment: Category=organism-gene. synonym: "Hmgcs2" RELATED Gene-based [UniProtKB:P22791] synonym: "rHMGCS2" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA synthase (rat)" RELATED [UniProtKB:P22791] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase (rat)" RELATED [UniProtKB:P22791] xref: UniProtKB:P22791 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000008638 ! hydroxymethylglutaryl-CoA synthase, mitochondrial relationship: has_gene_template RGD:2804 ! Hmgcs2 (rat) [Term] id: PR:P54868-2 name: hydroxymethylglutaryl-CoA synthase, mitochondrial isoform h2 (human) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54868-2." [PRO:DNx, UniProtKB:P54868] comment: Category=organism-sequence. synonym: "hHMGCS2/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54868-2 is_a: PR:P54868 ! hydroxymethylglutaryl-CoA synthase, mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P54868-1 name: hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 (human) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hHMGCS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54868-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039775 ! hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 [Term] id: PR:P54869-1 name: hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 (mouse) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mHMGCS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54869-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039775 ! hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 [Term] id: PR:000047881 name: hydroxymethylglutaryl-CoA synthase, mitochondrial, transit peptide removed form (human) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P54868, 38-508." [PRO:DNx, Reactome:R-HSA-56573] comment: Category=organism-modification. synonym: "PRO_0000013483" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHMGCS2/TransPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P54868, 38-508" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-56573 "PR:000047881 located_in GO:0005759" intersection_of: PR:P54868 ! hydroxymethylglutaryl-CoA synthase, mitochondrial (human) intersection_of: lacks_part SO:0000725 ! transit_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000008638 name: hydroxymethylglutaryl-CoA synthase, mitochondrial def: "A protein that is a translation product of the human HMGCS2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HMGCS2" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA synthase" BROAD [PRO:DNx] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase" BROAD [PRO:DNx] xref: IUPHARobj:2432 is_a: PR:000000001 ! protein [Term] id: PR:000039775 name: hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54868-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "HMGCS2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000008638 ! hydroxymethylglutaryl-CoA synthase, mitochondrial [Term] id: PR:P54868-3 name: hydroxymethylglutaryl-CoA synthase, mitochondrial isoform h3 (human) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54868-3." [PRO:DNx, UniProtKB:P54868] comment: Category=organism-sequence. synonym: "hHMGCS2/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "hydroxymethylglutaryl-CoA synthase, mitochondrial isoform HMGCS2delta4 (human)" EXACT [UniProtKB:P54868] xref: UniProtKB:P54868-3 is_a: PR:P54868 ! hydroxymethylglutaryl-CoA synthase, mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P54868 name: hydroxymethylglutaryl-CoA synthase, mitochondrial (human) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P54868] comment: Category=organism-gene. synonym: "HMGCS2" RELATED Gene-based [UniProtKB:P54868] synonym: "hHMGCS2" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA synthase (human)" BROAD [UniProtKB:P54868] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase (human)" BROAD [UniProtKB:P54868] xref: UniProtKB:P54868 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008638 ! hydroxymethylglutaryl-CoA synthase, mitochondrial relationship: has_gene_template HGNC:5008 ! HMGCS2 (human) [Term] id: PR:P54869 name: hydroxymethylglutaryl-CoA synthase, mitochondrial (mouse) def: "A hydroxymethylglutaryl-CoA synthase, mitochondrial that is encoded in the genome of mouse." [OMA:P54869, PRO:DNx] comment: Category=organism-gene. synonym: "Hmgcs2" RELATED Gene-based [UniProtKB:P54869] synonym: "mHMGCS2" EXACT PRO-short-label [PRO:DNx] synonym: "HMG-CoA synthase (mouse)" RELATED [UniProtKB:P54869] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase (mouse)" RELATED [UniProtKB:P54869] xref: UniProtKB:P54869 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000008638 ! hydroxymethylglutaryl-CoA synthase, mitochondrial relationship: has_gene_template MGI:101939 ! Hmgcs2 (mouse)